Drugs Flashcards
1
Q
Lorazepam
A
Amnesia
2
Q
Paroxetine in pregnancy
A
Congenital malformation
3
Q
Lithium checked how often
A
12h after dose change, weekly, 3 monthly
4
Q
Citalopram
A
QT prolongation and torsades de pointes
5
Q
ECT
A
Retrograde amnesia
Cardiac arrhythmia short term
6
Q
Monitored in SNRI
A
BP
7
Q
Avoid with triptins
A
SSRI
8
Q
Steroid
A
Psychosis Avascular necrosis Proximal myopathy Osteonecrosis Hyperglycaemia Osteoporosis Cushings Insomnia
9
Q
Amiodarone
A
Lower zone fibrosis
10
Q
Methotrexate
A
Pneumonitis
11
Q
Beclometasone
A
Oral candidiasis
12
Q
Azithromycin
A
Prolong QT
13
Q
Thiazides
A
Worsens glucose tolerance Gout Erectile dysfunction Hyponatraemia Hypokalaemia Hypercalcaemia
14
Q
Loop diuretic
A
Ototoxicity
Hyperkalaemia
15
Q
Macrolides
A
Torsades de pointes
16
Q
Reverse dabigatran
A
Idarvuzub
17
Q
Sotalol
A
Long QT syndrome
18
Q
Fondaparinux mechanism
A
Activates prothrombin III
19
Q
ACEI
A
Hyperkalaemia
Cough
Angioedema
20
Q
Beta blocker
A
Cold peripheries
Erectile dysfunction
Sleep disturbance
21
Q
Amiodarone
A
Grey skin
Thrombophlebitis - give in central line
22
Q
Adenosine
A
Flushing
Chest pain
23
Q
When stop statin
A
If start macrolide]
Pregnancy
24
Q
Never take verapamil with
A
Beta blocker
25
Ivabradine
Visual disturbance
26
Monitoring before amiodarone
Xray, LFT, TFT, UandE
27
Stop warfarin how long before surgery
5d
28
Bleeding times in warfarin
Increased PT
| Normal APTT
29
What increase in creatinine after starting ACEI is acceptable
Up to 30%
30
Statin monitoring
Baseline LFT, 3m and 12m
31
ACEI contraindicated
Aortic stenosis
| HOCM
32
Licensed CCB in HF
Only amlodipine
33
Nicorandil
Ulceration GI tract
34
Before starting sumubitril-vulsartan
ACEI/ARB washout
35
Lamotrigine
Steven Johnsone syndrome
36
Drug precipitate myasthenia crises
Beta blocker
37
Ondensetron mechanism
5HT3 antagonist
38
Triptin
Tightness of throat and chest
39
Tetracycline
Idiopathic intracranial hypertension
Stop in pregnancy
Black hairy tongue
40
Phenytoin
Megaloblastic anaemia
Peripheral neuropathy
Dupuytrens contracture
Folic acid deficiency
41
Carbamazepine
Steven Johnson syndrome
42
Triptin contraindicated
CVD
43
Sodium valproate
Weight gain
| Pancreatitis
44
Chemotherapy
Avascular necrosis
| Gout
45
Bisphosphonates
Oesophageal problems
46
Alondrenate
Atypical stress fracture
47
TNF alpha inhibitor
Reactivate TB
48
Methotrexate
Mucositis
| Pneumonitis
49
Sulfasalazine contra
Co-trimoxazole
| Aspirin allergy
50
Hydroxychloroquine
Retinopathy
51
Azithioprine and pregnancy
Okay in pregnancy unlike others
52
Colchinne
Diarrhoea
53
Sulfazalazine
Decreased sperm count
54
Check before starting azithioprine
Thiopurine methyltransferase
55
Suxamethonium
Fasciculations
Malignant hyperthermia
Hyperkalaemia
56
Etomidate
Adrenal suppresion
57
Halothene
Hepatotoxicity
58
Contraindication suxamethonium
Eye injury
59
Trimethoprim
Hyperkalaemia
60
Vancomycin
Red man syndrome infusing too fast
61
Dapaglifozin
Necrotissing fascittis
62
Doxycycline
Photosensitivity
63
Antibiotic worst with alcohol
Metronidazole
64
Metoclopramide
Parkinsonism
| Galactorhoea
65
Contraindications metoclopramide
PD
| Bowel obstruction
66
Aminosalicylate
Agranulocytosis
| Acute pancreatitis
67
PPI
C Diff
Osteoporosis
Decreased Mg
68
Sulfasalazine blood film
Heinz bodies
69
Tamoxifen
Endometrial cancer
| Hot flushes
70
Anastrozole
Osteoporosis
71
Progesterone
Breast cancer
| Irregular bleeding
72
Oxybutylin
Fall in elderly
73
Beta blocker contraindication
Asthma
| Heart block
74
Reverse magnesium sulphate
Calcium gluconate
75
Aspirin contraindication
Breastfeeding
| Children
76
Spironolactone
Gynaemocastia
| Hyperkalaemia
77
Use instead of spironolactone
Eplerenone
78
NSAID
Acute interstitial nephritis
79
Lithium
Nephrogenic diabetes insupidus
80
Statin
Muscle pain
| Rhabdomyolysis
81
Erythropoitin
Flu, bone pain, rash
82
Chlorpromazine
Gynaemocastia
83
Sulphonylurea
Weight gain
84
Ferrous sulphate
Reduce absorption levothyroxine - take 4h apart
85
Pioglitazone
Peripheral oedema
| Cannot use in bladder cancer
86
Carbimazole
Agranulocytosis
87
Goserlin
Gynaemocastia
88
SGLT2
UTI
Fourniers gangrene
Weight loss
