Neuroradiology Flashcards

1
Q

What are some indications to perform a CT scan?

A

Head trauma: NICE guidelines

Acute stroke: NICE guidelines

Headache: SIGN guidelines, red flags for suspected tumour or subarachnoid haemorrhage

Cancer: looking for metastatic brain tumours in patients with symptoms

Post-surgical: hydrocephalus, haemorrhage

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2
Q

What are some reasons not to perform a CT scan?

A

Minor head trauma exclusion criteria: NICE and SIGN guidelines

Seizure: NICE guidelines (pg 16), usually choose MRI

  • primary idiopathic generalised epilepsy – no imaging
  • complete recovery after a first seizure is not epilepsy
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3
Q

What are some indications to perform a MRI scan?

A

Mostly done by specialist physicians:

Neurologists:

Demyelination

CNS tumours

Spine - for intervertebral disc prolapse

Transient ischaemic attacks

Epilepsy

Paediatric neurology

Headache

Surgeons:

Spine: Intervertebral disc degeneration causing neural compression

Cancer: clarifying the number, location and aggressiveness of brain tumours

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4
Q

What are some contraindications to perform an MRI scan?

A

Implanted electronics (check with manufacturer):

  • Cardiac pacemakers, implantable defibrillators, cochlear implants
  • Relative contraindication for programmable shunts, insulin pumps

Moveable metallic implants (check make and model):

• Aneurysm clips, heart valves, recent intra-abdominal clips

Relative contraindications:

• Claustrophobia, pregnancy, tattoos

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5
Q

What are some uses of angiography in the diagnosis of neurological pathology?

A

Used for large vascular (arterial and venous) abnormalities Used for diagnosis and treatment

  1. Aneurysm
  2. Arteriovenous malformation - an abnormal connection between arteries and veins, bypassing the capillary system
  3. Carotidocavernous fistula
  4. Unstoppable epistaxis
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6
Q

What is perfusion?

A

Perfusion is defined as the volume of blood passing through a defined volume of tissue per unit time

Units: ml blood/100g tissue/min

Can be a CT or MRI technique

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7
Q

What are some disorders of abnormal perfusion?

A

Stroke - decreased perfusion

Tumour - increased perfusion indicates angiogenesis and a more aggressive tumour

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8
Q

WHat are PET scans used for?

A

PET is usually used to map out glucose usage

Increased metabolism is seen in:

  • Tumour
  • Inflammation
  • Infection

Useful after brain tumour resection for differentiating granulation tissue (low energy usage) from leftover tumour (high energy usage)

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9
Q

How are plain radiographs recognised?

A

Multiple superimposed bones, bones are white

Immediately recognisable body parts

Soft tissue is grey

Air is black

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10
Q

How do you indetify a CT scan?

A

White circle of skull

Black CSF in sulci and ventricles

Air is black

Grey brain with subtle grey-white matter difference

Image quality:

  • reconstructed by back projection from a rotating fan beam of X-rays
  • beam hardening from radiodense objects

Metal produces white starbust artefacts, slightly grainy

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11
Q

How do you indentify a MRI scan?

A

White CSF is the best clue, but only true for T2- weighted MRI - Same anatomy with different sequences often shown

Better grey-white matter differentiation than CT

Image quality:

  • reconstructed from Fourier transforms of radio signals
  • has a JPEG-like quality, usually not grainy
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12
Q

How do you identify radionuclide radiology/nuclear medicine/PET?

A

Images often have bright and varied colours

The image is fuzzy

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13
Q

How do you identify ultra sound?

(not as important)

A

Wedge-shaped image with the edges of the image diverging away from top to bottom

Often has a curve at the top matching the ultrasound probe (exception: flat probes)

Very noisy image (like an old un-tuned TV)

Objects which block the ultrasound beam (air, bone, stones) cast shadows cast downwards

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14
Q

What colour is CSF is CT and MRI?

A

CT - black

MRI - white

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15
Q

What are the advantages of ultrasound?

A
  • No radiation
  • Less expensive equipment
  • Can be performed in the neonatal unit
  • Movement tolerant
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16
Q

What are the disadvantages of ultrasound?

A

• Requires a wide enough open fontanelle

i.e. up to about 1 year of age

• Image quality and interpretation based on operator skill

17
Q

What are the advantages of plain radiographs?

A
  • Almost universal availability
  • Fast
  • Sequential images in subtraction angiography
18
Q

What are the disadvantages of plain radiograph?

A

• Lacks soft tissue detail

19
Q

What are the advantages of a CT scan?

A
  • Rapid
  • Metal and pacemaker tolerance
  • Good for demonstrating acute haemorrhage
20
Q

What are the disadvantages of a CT scan?

A
  • Radiation 2mSv
  • More expensive cumbersome equipment
21
Q

What are the advantages of radionuclide radiology?

A

It gives you physiological information such as:

  • Glucose metabolism
  • Perfusion
  • Dopamine reuptake receptors
22
Q

What are the disadvantages of radionuclide radiology?

A
  • Unclear anatomical information
  • Medium cost of equipment
  • Radiotracers can be expensive
23
Q

What are the advantages of MRI?

A
  • No radiation
  • Soft tissue differentiation

Gives you physiological information:

  • blood flow
  • diffusion restriction
  • metabolite concentrations
24
Q

What are the disadvantages of MRI?

A
  • Poor tolerance of metalwork
  • Magnetic sensitive electronics may fail or are contraindicated:
  • Pacemakers!
  • Cochlear implants absolutely contraindicated
  • Least movement tolerance
  • Slow, must limit sequences
  • Most expensive equipment
  • Danger of metallic objects becoming projectiles
25
Q

The techniques image what?

A

Structure (anatomy) and Function (physiology)

26
Q

What are the different types of imaging?

A

Plain films

Ultrasound

Radionuclide radiology

Computed tomography

Magnetic resonance imaging

27
Q

What are some common pathologies seen?

A
  • Stroke
  • Trauma
  • Haemorrhage
28
Q

What are some important pathologies?

A
  • Tumours
  • Intervertebral disc herniation
  • Infection