NeuroPathology - Stroke Objectives (EXAM ONLY) Flashcards

1
Q

What is a TIA?

A

a brief interruption in the blood supply to the brain, sx may last minutes to hours but MUST resolve within 24 hours

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2
Q

What is a stroke?

A

a cerebrovascular attack where blood flow is blocked OR sudden bleeding in the brain

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3
Q

What is an Ischemic stroke?

A

A stroke caused by blocked blood flow

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4
Q

What is a Hemorrhagic stroke?

A

A stroke caused by sudden bleeding in the brain

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5
Q

Where does stroke land in the statistics of leading causes of death?

A

the 5th leading cause of death

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6
Q

What are sudden warning signs of a stroke?

A

weakness/numbness of the face/arm/leg, dimness or loss of vision in one eye, difficulty speaking or understanding speech, severe unexplained headache

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7
Q

What is the most common site of atherosclerosis and atherothrombosis leading to stroke?

A

the Proximal internal carotid artery

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8
Q

When is Neuronal functioning impaired?

A

when cerebral blood flow falls <20mL/100mg of tissue/minute

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9
Q

When does Neuronal death, or infarction, occur?

A

when the brain receives <8 to 10 mL/100mg/min

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10
Q

What are signs of increased Intracranial Pressure (ICP)?

A

loss of consciousness, coma, irregular respirations, unreacting pupils, and vomiting

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11
Q

What percentage of strokes occur from the ACA?

A

<3%

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12
Q

What is the most common site of occlusion?

A

MCA

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13
Q

What are signs/symptoms of Wallenberg Syndrome?

A

Vertigo, nausea, hoarseness, dysphagia, ataxia, ptosis, ipsilateral facial sensory loss, contralateral torsi/extremities sensory loss

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14
Q

What percentage of strokes fall under Lacunar Syndrome?

A

~20%

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15
Q

What is an Intracerebral Hemorrhage?

A

bleeding into brain tissue

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16
Q

What is a Primary/Secondary hemorrhagic stroke caused by?

A

spontaneous trauma, impaired coagulation, or toxin exposure

17
Q

what is a subarachnoid hemorrhage?

A

bleeding into the subarachnoid space

18
Q

What are some causes for an ICH?

A

High BP, aneurysm, illicit drugs

19
Q

What are some causes for an SAH?

A

Head injuries, burst aneurysm, reupture of arteriovenous malformation

20
Q

What is the mortality rate of a hemorrhagic stroke?

A

38%

21
Q

What is the mortality rate of an ischemic stroke?

A

8-12%

22
Q

What does the PICA supply?

A

brainstem, medulla, and cerebellum