Neuronal Signaling and Neurons Flashcards

1
Q

what ion plays the most important role in generating the RMP?

A

K+

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is RMP?

A

potential to do work due to separated electrical charge on opposite sides of membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

T/F: the cell membrane is leaky to K+?

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what is equilibrium potential?

A

reflects an equilibrium between electrostatic attraction/repulsion and concentration differences

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Stages of an AP

A

RMP,
Depolarization,
Re-polarization,
Hyper-polarization

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what causes hyper-polarization?

A

K+ channels are slow to close, allows more K+ efflux to occur

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Na+ channels exert what type of feedback on membrane potential?

A

positive feedback

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

K+ channels exert what type of feedback on membrane potential?

A

negative feedback

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what is a refractory period?

A

period in which a 2nd stimulus arriving at the synapse will not initiate a 2nd AP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what is the relationship been neuron size and AP velocity?

A

larger fiber = faster AP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

T/F: threshold potentials are achieved by a single graded potential

A

FALSE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

the collective equilibrium potential creates what?

A

resting membrane potential

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what is an action potential?

A

events that change the potential on the cells to bring about a response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what causes depolarization?

A

influx of + charges

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

when does depolarization stop?

A

when Na equilibrium potential is reached causing Na channels to close

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

why doesn’t repolarization just stop at RMP? why do we have hyperpolarization?

A

K+ channels don’t all close at the same time, K+ continues to leak outside of the cell

17
Q

what type of feedback loop would an action potential be?

A

positive feedback

18
Q

what type of feedback loop is depolarization?

A

negative feedback

19
Q

why is repolarization negative feedback?

A

the channels close as a result of too much K leaking out

20
Q

T/F: APs decrease in magnitude with transmission

A

False, they remain all or none

21
Q

ratio of fiber diameter to speed of AP

A

larger fiber = faster AP

22
Q

why are larger fibers faster?

A

less internal resistance to current, membrane threshold is attained more quickly

23
Q

how does the presence of Schwann cells affect transmission of APs?

A

faster velocity

24
Q

what is the difference between an AP and a graded potential?

A

AP are all or nothing, GP can have a graded response based on the stimulus and have no refractory period

25
Q

T/F: effective/absolute refractory period is shorter in skeletal muscle compared to cardiac muscles and nerves

A

TRUE