Neuromodulators Flashcards
Cholinergic neurons secrete which neurotransmitter?
acetylcholine
What is the action of acetylcholine in the gut?
Contraction of smooth muscles in wall; relaxation of sphincters
Increased salivary, gastric and pancreatic secretions
Adrenergic neurons secrete which neurotransmitter?
Norepinephrine
What is the action of NE in the gut?
Relaxation of smooth muscles in the wall; contraction of sphincters
Increased salivary secretion
What cells release Vasoactive Intestinal Peptide?
Neurons of mucosa and smooth muscle
What is the action of VIP?
Relaxation of smooth muscle
Increased intestinal and pancreatic secretions
What cells release gastrin-releasing peptide (GRP) or Bombesin?
Neurons of mucosa and smooth muscle
What is the action of GRP?
Increased gastric secretion
What cells release enkephalins (opiates)?
Neurons of mucosa and smooth muscle
What is the action of enkephalins?
Contraction of smooth muscle
Decreased intestinal secretion
What cells release neuropeptide Y?
Neurons of the mucosa and smooth muscle
What is the action of neuropeptide Y?
Relaxation of smooth muscle
Decreased intestinal secretion
What cells secrete Substance P?
Substance P is co-secreted with ACh from cholinergic neurons
What is the action of substance P?
Contraction of smooth muscle
Increased salivary secretion
