Neurology: Floppy Infant Syndrome Flashcards
1
Q
Persistent hypotonia can be readily felt on…
A
Picking up infant - slip through fingers or hangs like a rag doll when suspended prone
Marked head lag when head lifted by arms from supine
2
Q
What symptoms/signs suggest central hypotonia?
A
Truncal weakness Sustained limb strength Increased tendon reflexes Up going plantars Sustained clonus Global developmental delay Syndromic features e.g trisomy 21
3
Q
What symptoms/signs suggest peripheral hypotonia?
A
Weak cry Weak cough Poor swallow Abnormal breathing pattern Frog leg position Decreased tendon reflexes Down going plantars Social development may be normal
4
Q
What central causes are there?
A
HIE Congenital infections or acquired Down syndrome Prader-Willi syndrome Drug effects e.g benzodiazepines Cerebral malformations Intracranial haemorrhage
5
Q
What peripheral causes are there?
A
Spinal muscular atrophy Charcot-Marie-Tooth Guillian Barré Myasthenia gravis Muscular dystrophies
6
Q
What other causes are there?
A
Connective tissue diseases
Metabolic - hypokalaemia, hypophosphataemia, rickets
Hypothyroidism
Infection
