Neurology Flashcards

1
Q

4 patterns of headaches in childhood

A

isolated acute
recurrent acute
chronic progressive
chronic non-progressive

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2
Q

Typical episode of headache questions

A
any warning?
location?
severity?
duration?
frequency?
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3
Q

headache examination

A
growth, OFC, bp
sinuses, teeth, vision 
fundoscopy 
visual fields 
cranial bruit
focal signs
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4
Q

pointers to childhood migraine

A
associated abdo pain, N&V
Focal symptoms before/during/after - tingling
aggravated by light/noise
relation to fatigue/stress
helped by sleep, quiet
FH
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5
Q

Migraine vs TTH location

A

migraine is hemicranial

TTH - diffuse, symmetrical

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6
Q

pointers to raised ICP

A

aggravated by coughing, bending

woken from sleep

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7
Q

Indications for neuroimaging

A

cerebellar dysfunction
raised ICP
new focal neurological deficit eg new squint
seizures - esp focal

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8
Q

managing migraine

A

acute attack - triptans

prevent - amitriptyline, valproate, propanolol

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9
Q

TTH treatment

A

reassure, MDT, underlying stress
simple analgesia
amitriptyline?

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10
Q

convulsion

A

fit where there is a prominent motor activity

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11
Q

Epileptic seizure

A

abnormal excessive hypersynchronous discharge from neurons

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12
Q

Non epileptic seizures

A
syncope 
parasomnias 
psychogenic 
hypoglycaemia
reflex anoxic seizures - preceded by trauma
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13
Q

What is a febrile convulsion?

A

3 months - 5 years
fever
no intracranial infection or defined cause

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14
Q

commonest cause of acute symptomatic seizure in childhood

A

febrile convulsion

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15
Q

jerk/shake seizure types

A

myoclonic, clonic, spasm

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16
Q

stiff seizure type

17
Q

fall seizure type

A

atonic/tonic/myoclonic

18
Q

chemical trigger of epileptic fit

A

decreased inhibition - GABA
Excessive excitation - glutamate
excess Na and Ca influx

19
Q

Child epilepsies vs adult epilepsies

A

idiopathic
most generalised
can be subtle

20
Q

Role of EEG

A

interictal has limited value

seizure type, aetiology

21
Q

Diagnosing epilepsy

A
history 
video recording 
EEG in seizure
MRI brain 
genetics eg tuberous sclerosis 
metabolic tests
22
Q

Epilepsy drug treatment

A
sodium valproate - generalised (not girls)
carbamazepine - focal 
lamotrigine, steroids, immunoglobulins
VNS
Surgery
23
Q

When to suspect NM disorder

A
baby floppy from birth 
slips from hands 
alert but less motor activity
delayed milestones
able to walk but frequent falls
24
Q

Sign which indicates pelvic girdle weakness

25
Appearance of child with NM disorder
calf muscle hypertrophy poor balance belly sticks out walk on tip toes
26
problem in Duchenne
dystrophin gene
27
elevate …. in Duchenne
creatinine kinase