Neonates Flashcards
Briefly describe the foetal circulation
oxygenated blood via umbilical vein
ductus venosus
foramen ovale –> LA - LV to aorta
right ventricle –> PA to PDA and to aorta
Sa02 in foetal body
60-70%
What does ductus arteriosus protect against?
lungs against circulatory overload
What does ductus arteriosus allow?
right ventricle to strengthen
ductus arteriosus - oxygenated or deoxygenated blood?
deoxygenated
What does ductus venosus connect?
umbilical vein to IVC
How is blood flow in ductus venosus regulated and does it carry oxygenated or deoxygenated blood?
sphincter
oxygenated
What happens with baby first breath?
foramen ovale closes
many embryological structures become ligaments
breathing in new born
30-60/min
periodical
HR in newborn
120-160bpm
<100 = bradycardia
>160bpm = tachycardia
thermoregulation in newborn
lack shivering thermogenesis
brown fat - sympathetic neurons
Non invasive ways to measure new born breathing
blood gas
trans cutaneous
Invasive ways to measure new born breathing
capnography
tidal volume
minute ventilation
flow volume loop
is it normal not to pass urine for first 24 hours?
yes
Fluid balance in premature infants
less fat
slow GFR, reduce Na reabsorption
increased insensible water loss
low birth weight
<2500g
SGA and IUGR
SGA = neonatal IUGR = obstetric
hypotrophy
below the 10th centile
Reasons for babies small for dates
maternal = smoking, PET genetic eg trisomy 18 infection eg CMV placental abruption twins
Common problems for small for date babies
hypoglycaemia perinatal hypoxia hypothermia thrombocytopenia polycythaemia
Long term problems for babies small for date
hypertension
reduced growth
obesity
IHD
% of pregnancies premature
10
Under what weeks is premature?
37
When is extremely premature?
under 28 weeks
low, very low and extremely low birth weight
low = <2500g
very low <1500g
extremely low <1000g
Problems with the premature baby include..
RDS
Necrotising entero-colitis
IVH
pot haemorrhagic hydrocephalus
How to prevent RDS
antenatal steroids
early treatment for RDS
surfactant and extubation
N-CPAP
Preventing and treating IVH
steroids antenatally
Drain?
Pressure aorta > pulmonary artery = what kind of shunt?
left to right
Patent ductus arteriosus - what happens?
lung oedema
systemic ischaemia
Symptoms of sepsis
hypothermia/pyrexia
poor feeding and lethargy
early jaundice
hypo or hyperglycaemia
Risk factors for sepsis
prolonged rupture of membranes
maternal pyrexia
maternal group B strep carriage