Neurology Flashcards

1
Q

What tracts are affected in subacute degeneration of the spinal cord?

A

Dorsal Column and Lateral corticospinal tract

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2
Q

Function of spinothalamic tract?

A

Transmits pain, temperature, and crude touch sensations

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3
Q

Function of dorsal column?

A

Responsible for fine touch, proprioception, vibration, and pressure sensations

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4
Q

Where does decussation occur in the spinothalamic tract?

A

Level of spinal cord entry within the anterior commissure

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5
Q

Spinothalamic tract:
-A lesion will lead to loss of what and where?

A

Pain and temperature on the CONTRALATERAL side below the lesion

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6
Q

Where does decussation occur in the dorsal column?

A

At the level of the medulla in the medial lemniscus

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7
Q

A lesion in the dorsal column will result in what?

A

loss of fine touch, vibration, and proprioception on the ipsilateral side below the level of the lesion.

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8
Q

Function of lateral corticospinal tract?

A

Controls voluntary motor function, particularly fine movements of the distal limbs

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9
Q

Decussation lateral corticospinal tract?

A

pyramidal decussation at the medulla, the fibers cross to the contralateral side and form the lateral corticospinal tract.

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10
Q

Lesions affecting the lateral corticospinal tract will result in?

A

contralateral motor weakness, particularly affecting fine motor skills and dexterity. Upper motor neuron signs (e.g., hyperreflexia, spasticity) are seen

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11
Q

Functions of anterior corticospinal tract?

A

Controls voluntary motor function, particularly for trunk and proximal limb muscles

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12
Q

where does decussation occur in anterior corticospinal tract?

A

In the spinal cord, fibers from the anterior corticospinal tract cross at the level of the spinal cord to synapse with lower motor neurons in the anterior horn.

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13
Q

Lesions of the anterior corticospinal tract typically result

A

weakness and impaired movement of the trunk and proximal muscles on the contralateral side.

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14
Q

Site of lesion in Wernicke and Korsakoff syndrome

A

Medial thalamus and mammillary bodies of the hypothalamus

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15
Q

site of lesion in Hemiballism

A

Subthalamic nucleus of the basal ganglia

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16
Q

Site of lesion in Huntington chorea

A

Striatum (caudate nucleus) of the basal ganglia

17
Q

Site of lesion in Parkinsons disease?

A

Substantia nigra of the basal ganglia

18
Q

Site of lesion in Kluver-Bucy syndrome (hypersexuality, hyperorality, hyperphagia, visual agnosia

A

Amygdala

19
Q

Why does Bells Palsy cause hyperacusis?

A

facial nerve innervates the stapedius muscle (which affects how loud conduction of sound from the tympanic membrane to the cochlea

20
Q

Triad of Miller Fisher syndrome?

A

Ataxia
Ophthalmoplegia
Areflexia

21
Q

Type of dysphasia:
speech non-fluent, comprehension normal, repetition impaired

A

Brocas

22
Q

Brocas aphasia area of brain affected?

A

inferior frontal gyrus in the dominant hemisphere (which is usually on the left side for right-handed individuals).

23
Q

Mechanism of action of Riluzole for motor neuron disease?

A

Inhibits glutamate release; modestly extends survival.

24
Q

Does Amyotrophic lateral sclerosis (ALS) result in UMN or LMN signs?

A

Both UMN and LMN

25
Q

Does Progressive muscular atrophy (PMA) result in UMN or LMN signs?

A

LMN only

26
Q

Does Primary lateral sclerosis (PLS): result in UMN or LMN signs?

A

UMN signs only

27
Q

Internuclear ophthalmoplegia is caused by pathology in what part of the brain?

A

The medial longitudinal fasciculus is located in the paramedian area of the midbrain and pons

28
Q

Cranial nerve lesion ? results in down and out eye and Ptosis?

A

Third nerve Palsy

29
Q

speech fluent, but repetition poor. Comprehension is relatively intact

A

Conduction dysphasia
-Arcuate fasciculus affected

30
Q

non-fluent, laboured and halting speech

A

Brocas Aphasia
-Inferior frontal gyrus
-Superior division of left MCA

31
Q

neologisms and nonsense sentences which is fluent

A

Wernicke’s aphasia
-Lesion in superior temporal gyrus
-Supplied by inferior division of left MCA

32
Q

First line management of trigeminal neuralgia?

A

Carbamazepine

33
Q
A