neurology Flashcards

1
Q

meningitits causes

A

most common is viral

bacterial
- neonates: listeria, group B strep
- children: H. influenzae, meningococcal, pneumococcal

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2
Q

meningitis general presentation

A
  • fever
  • lethargy
  • confusion
  • seizures
  • difficult feeding
  • bulging fontanelles
  • nausea, vomiting, abdominal pain
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3
Q

meningitis septic presentation

A
  • fever
  • tachypnoea
  • cold peripheries
  • tachycardia hypotension
  • change in skin colour (pale)
  • rash (may/may not be a non-blanching purpuric rash)
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4
Q

meningitis meningeal presentation

A
  • tend to be the last symptoms to present
  • photophobia
  • neck stiffness
  • Kernig’s sign (resistance to knee extension when hip is flexed)
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5
Q

meningitis diagnosis

A
  • urine analysis (mid-stream sample of urine)
  • FBC, CRP, glucose, culture, meningococcal PCR
  • meningococcal PCR should always be sent off and can be used as an alternative for blood cultures
  • lumbar puncture (unless meningococcal septicaemia)
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6
Q

meningitis management

A
  • IM benzylpenicillin
  • if under 3 months: cefotaxime and amoxicillin
  • if > 3 months: 1 dose cefotaxime, daily doses of ceftriaxone (possibly with dexamethasone)
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7
Q

infective encephalitis causes

A
  • herpes simplex is most common
  • mumps
  • varicella zoster
  • parovirus B19
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8
Q

infectvie encephalitis presentation

A

as per meningitis but with odd behaviour and viral prodrome

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9
Q

infective encephalitis diagnosis

A
  • as per meningitis
  • MRI: bilateral temporal lobe focus (HSV encephalitis)
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10
Q

infective encephalitis management

A

IV acyclovir

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11
Q

what are febrile convulsions

A
  • infantile seizures that develop as a consequence of a febrile illness

defined by presence of the following features:
- occurs after 1 month of age
- no previous neonatal or unprovoked seizures
- not meeting criteria for other acute diagnoses
- associated with a febrile illness that isn’t CNS in nature

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12
Q

simple febrile convulsion presentation

A
  • generalised tonic-clonic seizure that lasts under 5 minutes
  • complex recovery of consciousness within 1 hour
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13
Q

complex febrile convulsion presentation

A
  • focal onset
  • lasts > 10 minutes
  • recurrent seizures in the one febrile illness (multiple in 24 hours)
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14
Q

febrile convulsion red flags

A
  • under 2 years
  • complex seizures
  • drowsiness or altered loss of consciousness > 1 hour
  • presence of neurological deficit > 1 hour
  • history of irritability, lethargy, being off food
  • signs of meningism: bulging fontanelles, neck stiffness, photophobia, focal neurological signs
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15
Q

febrile convulsion management

A
  • stay calm
  • don’t restrain child
  • protect child from any harm
  • check in their mouth
  • once seizure has stopped, check airway is open and put them in recovery position
  • following a seizure a child may be sleepy for about an hour
  • rectal or buccal midazolam (should be given if seizure lasts > 5 minutes)
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16
Q

when to phone 999 during a febrile convulsion

A

after 10 minutes if:
- seizure hasn’t stopped
- on going twitching
- another seizure starts
- any time you feel appropriate

17
Q

raised intracranial pressure causes

A
  • space occupying lesion
  • cerebral oedema
  • intra-cranial haemorrhage
18
Q

raised intracranial pressure presentation

A
  • bulging fontanelle
  • bradycardia with or without hypertension
  • abnormal pupils, posturing, breathing pattern
19
Q

acute flaccid paralysis differential diagnosis

A
  • Guillan-Barre
  • acute spinal cord lesions (e.g. space occupying lesion, demyelination, transverse myelitis)