Neurological System Flashcards
Dendrites
Receives electrical signals FROM other neurons
Axon
Transmits electrical signal TO other neurons
Glial cells
Supporting cells for functioning of the brain. Three types in CNS are: astrocytes, oligodendrocytes, microglia. One in PNS is: Schwann Cell
Astrocytes
Looks like “stars” surrounding the capillaries of the brain. Nutrient supplier and toxin filter, forms tight junctions with the capillaries. The filtering property is referred to as “blood-brain barrier.”
Schwann cells
Forms supporting structure for nerves (unlike astrocytes, which is for capillary). Myelinated nerves have Schwann cells that wrap around the nerve outside the myelination, and un-myelinated nerves have Schwann cells that do not wrap, but simply support the nerve fiber.
Gray and white matter in terms of myelination
gray = no myelination, white = myelination
Resting Membrane Potential
-70mV, for neurons. Na-K pump maintains this -70mV difference. Na-K pump lets three Na out two K in, so net potential is negative.
Depolarization of neuron
Neuron gets excitory stimulus, and when enough signal causes sodium gates to open (and Na rushes in to depolarize) this occurs. +30mV is reached at the end of depolarization.
Repolarization of neuron
After depolarization, potassium gates open and K gets out to polarize the electrical system. Sodium gates close at the same time.
Hyperpolarization of neuron
After repolarization, potassium gates close and a brief moment where larger than 70mV voltage difference occurs.
Refractory period
Repolarization + hyperpolarization period is referred to as this, since no stimulus can cause the system to react. This period is also necessary to stop electrical signal from traveling the opposite way.
Nodes of Ranvier
Saltatory conduction occurs due to this structure. The myelin sheath prevents normal influx of Na+ and helps propagate signal more efficiently.
Chemical Synapse, Synaptic Cleft
Electrical signal causes release of chemicals (neurotransmitters) which travel through this
Role of Ca++ in Synapse
When action potential reaches the synaptic knob, calcium gates open and let calcium in. Vesicles containing neurotransmitter merge with synaptic knob, releasing the chemicals.
Neurotransmitters
Can be inhibitory or excitatory. K+/Cl- opening will hyperpolarize and thus inhibit. K+/Na+ opening will depolarize and thus excite. Either direct or second messenger stimulation of gated channels can occur.
Ventricles of the Brain
Fluid-filled parts on the brain.
Sulcus, Gyrus
Respectively, parts of the brain that fold inward (valley), parts of the brain that fold outward (trough).
Cerebrum
Contains cortex and corpus callosum, the outer parts of the brain that we normally associate with folding.
Diencephalon
Contains thalamus, pineal body, hypothalamus
Brain stem
Contains midbrain, pons, medulla oblongata