Neurogenetics Flashcards
1
Q
Which codon is repeated in Huntington’s disease?
A
CAG
2
Q
How many repeats of CAG in the huntingtin gene is normal?
A
<27
3
Q
How many repeats of CAG in the huntingtin gene means someone will develop Huntonton’s disease?
A
40 or more
4
Q
Which chromosome is the huntingtin gene on?
A
4
5
Q
What pattern of inheritance does Huntington’s disease display?
A
Autosomal dominant
6
Q
What pattern of inheritance does Friedreich’s ataxia display?
A
Autosomal recessive
7
Q
Which codon is repeated in Friedreich’s ataxia?
A
GAA
8
Q
Which chromosome is the Friedreich’s ataxia gene on?
A
9
9
Q
How many GAA repeats in the FTX gene must a person have to develop Friedreich’s ataxia?
A
66 or more
