Neuro tumors Flashcards

1
Q

port-wine stains

A

sturge weber

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2
Q

nevus flammeus

A

sturge weber

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3
Q

sequelae of sturge weber

A

glaucoma, seizures, hemiparesis, mental retardation

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4
Q

ipsilateral leptomeningeal angioma, pheochromocytoma

A

sturge weber

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5
Q

inheritance pattern of sturge weber

A

sporadic

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6
Q

what is the clinical presentation of tuberous sclerosis

A

HAMARTOMAS:
hamartomas in CNS, adenoma sebaceum, mitral regurgitation, ash-leaf spots, cardiac rhabdomyoma, autosomal dominant, mental retardation, renal angiomyolipoa, seizures

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7
Q

ash-leaf spots

A

tuberous sclerosis

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8
Q

inheritance pattern of tuberous sclerosis

A

AD

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9
Q

lisch nodules

A

NF1 (von recklinghausen)

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10
Q

nf1 inheritance

A

AD

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11
Q

where is NF1 gene located

A

chromosome 17

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12
Q

optic gliomas, pheochromocytomas

A

NF1

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13
Q

cavernous hemangiomas in skin, mucosa, organs, bilateral renal cell carcinoma, hemangioblastoma in retina, brain ste , cerebellum, pheochromocytoma

A

von hippel lindau

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14
Q

cafe au lait spots

A

NF1

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15
Q

inheritance of von hippel lindau

A

AD

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16
Q

von hippel lindau has what mutated gene?

A

VHL gene, chromosome 3, tumor suppressor

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17
Q

iris hamartomas

A

nF1 (lisch nodules)

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18
Q

most common primary brain tumor

A

glioblastoma multiforme (astrocytoma grade IV)

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19
Q

butterfly glioma

A

glioblastoma

20
Q

lobulated mass near corpus callosum

A

glioblastoma

21
Q

psuedopalisading pleomorphic tumor cells

A

glioblastoma multiforme

22
Q

2nd most common primary brain tumor

A

meningioma

23
Q

whorled pattern, psammoma bodies

A

meningioma

24
Q

cell type in meningioma

A

arachnoid cells

25
Q

third most common primary brain tumor

A

schwannoma

26
Q

bilateral acoustic schwannoma is found in what disease process?

A

NF2

27
Q

NF2 presents with…

A

bilateral acoustic schwannoma

28
Q

S100 positive

A

schwannoma

29
Q

tumor found at cerebellopontine angle

A

schwannoma

30
Q

CN assocaited with schwannoma

A

CN VIII

31
Q

treatment for schwannoma

A

usually resectable or treated with stereotactic radiosurgery

32
Q

fried egg appearance

A

oligodendroglioma

33
Q

slow growing tumor in frontal lobes

A

oligodendroglioma

34
Q

chicken wire capillary pattern

A

oligodendrioglioma

35
Q

bitemporal hemianopia

A

pituitary adenoma (commonly prolactinoma)

36
Q

rosenthal fibers

A

eosinphilic, pilocytic

37
Q

cell type of medulloblastoma

A

neuroectodermal

38
Q

homer-wright rosettes

A

medulloblastoma

39
Q

small blue cells

A

medulloblastoma

40
Q

tumor most commonly found in 4th ventricle

A

ependymoma

41
Q

perivascular psuedorosettes

A

ependymoma

42
Q

rod-shaped blepharoplasts (basal ciliary bodies)

A

ependymoma

43
Q

childhood tumor that can cause bitemporal hemianopia

A

craniopharyngioma

44
Q

where is craniopharyngeoma derived from

A

rathke’s pouch

45
Q

most common childhood supratentorial tumor

A

craniopharyngeoma