Neuro Physio Flashcards
More numerous in the brain
Glial cells
Produces CSF
Ependymal cells
Regulates ECF ion levels gives mechanical support; forms BBB
Astrocytes
Creates myelin in the CNS
Oligodendrocytes
Creates myelin in the PNS
Schwann cells
Dec Ach in the brain
Alzheimer’s Disease
Ach use what enzyme during synthesis?
Choline acetyltransferase
Ach is produce by
nucleus basalis of meynert (BG)
Dopamine is found in the
Substantia Nigra Pars Compacta
And Ventral tegmental Area
Hypothalamus-prolactin inhibiting factor (PIF)
Dopamine is degraded by
MAO in presynaptic nerve terminals
COMT in tissue
Activate/inhibits adenylate Cyclase
D1-activates (Gs)
D2-inhibit (Gi)
NE and Epi is secreted by
Pons-locus cerelius
BS
Hypothalamus
Serotonin (W) is secreted by
Median Raphe of the BS
Also called as happy hormones
Serotonin: from tryptophan
Serotonin is converted to
Melatonin in the pineal gland
Histidine is secreted in the
Tuberomamillary nucleus of the hypothalamus
Histamine actions
Arousal
Sleep
Circadian rythm
Glutamate has 4 receptor
3 ionotropic-NMDA, Kainate, AMPA
1 metabotropic-mGluR
Nerve cells has 2 types
Neurons-permanent
Neuroglia/Glial cells/supporting
Another AP can not be elicited, no mAtter how large the stimulus
Absolute Refractory Period
No AP can occur until the Na inactivation gates open
Ionic Basis of Absolute Refractory Period
Action potential can be elicited only if a larger than usual inward current is provided
Relative Refractory Period
Membrane potential is closer to the K equilibrium potential and farther from threshold
Ionic Basic of a Relative Refractory Period
When a cell depolarized slowly, Threshold potential is passed without firing an action potential
Accommodation