Neuro Pathophysiology Flashcards
Parkinson Disease
Slow, progressive neurologic movement disorder associated with decreased levels of dopamine/ imbalance of dopamine and acteycholine
Alzheimer’s Pathophysiology
Cholinergic function deficiency. Decreased acetycholine production.
Dememtia
General term for memory loss
Delirium
Acture confusional state
Abrupt onset of symptoms
Can progress to LOC changes, irreversible brain damage, and death
Needs to be treated early
Considered a medical emergency
Major complication
Can be mistakened for dementia
Akinesia
Ridgid limbs
Anticholinergic drug
Drug tha tinhibits the actions of acetylcholine in the brain
Antimuscarinic drug
Drug that interacts with muscarinic cholinergic receptors to produce an anticholinergic drug response
Basal Ganglia
Area in the midbrain that controls smooth voluntary movement
Bradykinesia
Inability to move
Catechol-O-methyltransferase inhibitor
Medication that inhibits the metabolism of levodopa in the periphery
Cycloplegia
Paralysis in the ciliary muscle of the eye
Dopamine receptor agonist
Drug that corrects the neurotransmitter imbalance by increasing levels of dopamine
Extrapyramidal reactions
Movement disorders such as tardive dyskinesia, akathinis, dystonia, and drug-induced parkinsonism that may occur with use of antiparkinsonism and antipsychotic drugs
Hypertensive Crisis
Severe increase in blood pressure than can lead to a stroke
Muscarinic Receptors
Located in the most internal organs, including the cardiovascular, respiratory, gastrointestinal (GI), and genitourinary systems; when activated by acetylcholine, the affected cells may be excited or inhibited in their functions
