Neuro M ECT Flashcards
4 changes in Major Depressive Disorder
Change in mood
Change in circadian rhythm
Change in cognition
Psychomotor retardation or agitation
Antidepressant response vs remission
HDRS scale decrease by 50% vs >60%
Vagus Nerve Stimulation FDA approval
Intractible epilepsy, NOT depression
Remission rates
ECT
Antidepressants
70%
20-30%
Way to flush Benzodiazepines for ECT Tx
Flumazenil
ECT side effects
Amnesia (both)
Delirium (10%)
Headache (50%)
ECT MOA
Neurogenesis
Depression with Anorexia
Melancholic
Depression with Anxiety
Non-melancholic
Depression worse in morning
Melancholic
TMS method of action
Stimulate left PFC, induce partial seizure
TMS vs. Anti-Depressants
Equal
ECT synergism for schizophrenia
Clozapine
ECT goal
Grand Mal seizure for at least 20 seconds