Neuro H OCD Flashcards
OCD age of onset
15-30
OCD increased brain flow on MRI
Orbito-frontal cortex
Cingulate Gyrus
Caudate (right)
Screening and Policing circuit
Frontal -> Basal Ganglia -> Thalamus
Specific disease area causing unwanted thoughts/actions
Basal Ganglia
Secondary OCD
PANDAS (strep autoimmunity) Parkinson's following influenza Carbon Monoxide toxicity Manganese toxicity Infarction HIV
PANDAS pathogneumonic finding
Sydenham’s chorea
Rheumatic Fever susceptibility marker
B lymphocyte antigen recognized by D8/17 mab
Children with OCD
Check for carditis
OCD Tx
Clomipramine (TCA)
SSRIs
OCD surgery
Cingulotomy
Tourette’s onset
Before 18
Tourette’s marker
D8/17 B lymphocyte antigen
Tourette’s tic progression
Rostral to Caudal
Tourette’s neuropathology
Corpus striatum increased DA innervation
Tourette’s Tx
Clonidine
Haloperidol
Body Dismorphic Disorder age of onset
15-30
BDD Tx
SSRI
Cognitive Behavioral Therapy
Imaginal Exposure
BDD main comorbidity
Depression