Neuro H OCD Flashcards
1
Q
OCD age of onset
A
15-30
2
Q
OCD increased brain flow on MRI
A
Orbito-frontal cortex
Cingulate Gyrus
Caudate (right)
3
Q
Screening and Policing circuit
A
Frontal -> Basal Ganglia -> Thalamus
4
Q
Specific disease area causing unwanted thoughts/actions
A
Basal Ganglia
5
Q
Secondary OCD
A
PANDAS (strep autoimmunity) Parkinson's following influenza Carbon Monoxide toxicity Manganese toxicity Infarction HIV
6
Q
PANDAS pathogneumonic finding
A
Sydenham’s chorea
7
Q
Rheumatic Fever susceptibility marker
A
B lymphocyte antigen recognized by D8/17 mab
8
Q
Children with OCD
A
Check for carditis
9
Q
OCD Tx
A
Clomipramine (TCA)
SSRIs
10
Q
OCD surgery
A
Cingulotomy
11
Q
Tourette’s onset
A
Before 18
12
Q
Tourette’s marker
A
D8/17 B lymphocyte antigen
13
Q
Tourette’s tic progression
A
Rostral to Caudal
14
Q
Tourette’s neuropathology
A
Corpus striatum increased DA innervation
15
Q
Tourette’s Tx
A
Clonidine
Haloperidol
