Neuro G Dementia Flashcards
Cerebrovascular risk factor Personality change Dyskinesia Bradykinesia Visual hallucinations Mood change and family history of depression Longstanding alcoholism
Vascular dementia Frontotemporal dementia Huntington’s Parkinson’s Lewy body dementia Depressive dementia Alcoholic dementia
Required tests for dementia
Imaging studies Blood tests Urinalysis Electrocardiogram Chest X-rays Genetic studies for HD
MMS score below which establishes dementia
20
Trail making test domain
Executive function
Clock drawing purpose
Screen for Alzheimer’s
Differentiation between AD MCI & AD Dementia
Maintaining independence
Mean AD survival
10 years
AD brain finding
Cortical hypoperfusion, ventricular dilatation, sulcal enlargement
AD motor finding
restlessness in stage 2
rigidity in stage 3
AD Neurofibrillary tangles & Neuritic plaques
Not unique to AD
4 genetic AD risk factors
Family history of Dementia
Down’s syndrome
Presenilin mutation & abnormal APP gene
Apolipoprotein E 4 allele
Vascular dementia vs. AD
Stepwise progression More depression More functional impairment Less cognitive impairment More MRI findings
Pick’s disease
Frontotemporal dementia
- Personality, Emotional, Executive problems
- Delusions not common
Pick’s disease gene
Tau protein
Pick’s disease histology
Pick bodies
No tangles