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Test 6 > Neuro L Schizophrenia > Flashcards

Neuro L Schizophrenia Flashcards

1
Q

1 cause of psychosis (40%)

A

Mood disorders

Dug induced states

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2
Q

5 schizophrenia inclusion criteria

A 
Delusions
Hallucinations
Disorganized speech
Disorganized behavior
Negative symptoms
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3
Q

Neuroleptic side effect that mimics emotional blunting

A

Akinesia

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4
Q

Exclusion criteria

A

Any mood disorder

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5
Q

Length criteria

A

6 months

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6
Q

4 motor abnormalities

A

Stereotypies
Motor impersistence
Impaired eye tracking
Cerebellar problems

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7
Q

Bad prognosis

A

More negative symptoms than positive

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8
Q

Seasonal correlation

A

Influenza exposure in first trimester

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9
Q

MRI findings

A

Enlarged lateral ventricles
Widened sulci
Cerebellar vermis atrophy

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10
Q

fMRI abnormalities

EEG

A

Hypofrontality (DLPFC)

Reduced alpha, increased slow waves

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11
Q

Abnormal cellular development

A

Prefrontal & medial temporal lobe

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12
Q

Best prevention of schizophrenia

A

Good prenatal care

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13
Q

Endophenotype

A

Face recognition, sensorimotor dexterity

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14
Q

Pleiotrophy

A

One gene for multiple phenotypes

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15
Q

Schizophrenia family overlap

A

Mood disorders

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16
Q

ECT contraindications

A

None

17
Q

Dopamine hypothesis

A

Hyperactivity of D2-R in limbic striatum

18
Q

Serotonin hypothesis

A

Impaired 5-HT-R in PFC

19
Q

Glutamate hypothesis

A

NMDA antagonists (ketamine) cause psychotic symptoms

20
Q

Delusional Disorder age of onset

Family associated disorder

A

30-50

Paranoid personality disorder
NOT schizophrenia

21
Q

Schizoaffective disorder

A

Mood disorder with delusion/hallucination during off period for at least 2 weeks

22
Q

Schizophreniform disorder

A

Schizophrenia <6 months

23
Q

Brief psychotic disorder

A

Any schizophrenic features with full recovery within 1 month

Test 6 (18 decks)

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