Neuro Drugs Flashcards
What are the antiparkinson drugs?
benztropine
levodopa/carbidopa
Which one helps w/parkinson tremors?
benzotropine
Who to avoid benzotropine in?
old people
What is benzotropine?
anticholingeric
What is bad about levodopa?
only works for a few years
What is a benzo?
diazepam and lorazepam
How does benzo work?
enhances GABA –> inhibits excitability
ADR for benzo?
CNS depression
What are anticonvulsant?
carbamazepine valporate topiramate lamotrigine Gabapentin pregabalin
Which one to monitor rash?
lamotrigine
Which one enhances GABA? What to monitor? ADR?
toprimate
serum bicarb
wt loss and metabolic acidosis
ADR for valproate? monitor?
ADR: heptoxicity 0 LFT, pancreatitis - CBC and serum levels
What is bad about carbamazepine?
anticholintergic-no good in old people
HLA status in sasians
CBC checked -in risk patients –> can turn into bone marrow depression
What are the triptan drugs?
first - suma
second-riza
What are triptan?
5HT 1D and 2B agonist
Why is Riza better than Suma?
Riza is more lipophilic and better for migraines
Which is structurally simialr to GABA?
gabapentin
Which is a GABA analog?
pregabalin –> faster tolerable titration –> better than gabapentin
What is a alzheimer drug?
donezepil
What to monitor in donezepil? ADR?
HR and BP –> ADR: HTN
What is donezepil?
choliesterase inhibitor
Wha tis anti-narcoleptic stimulant?
modafinil
ADR for modafinil?
addiction and monitor BP
