Cardio Flashcards
What are RF for stable angina?
1) DM
2) low LDL
3) HTN
4) family hx
5) age (males >45yo; females > 55yo)
6) family hx
How to tx stable angina?
lifestyle changes and ASA in all
mild- nitrates + beta blockers (atenolol or metoprolol)
CCB if nitrates + beta blockers don’t help
mod - revascularization via PCI (angioplasty) or CABG
severe - CABG
What labs/imaging to run for stable angina?
- stress test
- pharmacologic stress test (if cannot do exercise stress test)
- holter
- cardiac catherization w/ coronary angiography
What are some beta blockers?
atenolol
metoprolol
Pt has chest pain upon exertion but goes away with rest?
stable angina
Pt has chest pain during rest?
unstable angina OR non-stemi
How to differentiate between unstable angina and non-stemi?
cardiac enzymes
if elevated = non-stemi
Labs/imaging for unstable anigina?
EKG - looks like non-stemi –> get cardia enzymes
coronary angiograph
Tx for unstable angina?
admit + IV + O2 +/- morphine
1) ASA
2) first line - nitrates + beta blockers
-clopidogrel
-LMWH (low molecular wt heparin) –> Enoxaparin
+/- angioplasty or CABG - use TIMI score
3) discharge: ASA + nitrates + beta blocker
Pt has chest pains occasionally at night?
variant/prinzmetal angina
RF for varient/prinzmetal angina?
smoking
Hallmark for varient/prinzmetal angina?
transient ST segment ELEVATION w/ chest pain
What else is associated with chest pains in varient/prinzmetal angina?
ventricular dyshythmias
Tx for varient/prinzmetal angina?
CCB + nitrates
Dx for varient prinzmetal angina?
coronary angiography - coronary vasopasms w/ chest pains
Pt has substernal chest pain for 30min and diaphoresis?
MI
What EKG findings for MI?
peaked T wave - EARLY, usually missed
ST elevation -diagnostic
Q waves - previous MI
ST depression
CXR for MI pts?
CLEAR lungs
What does ST elevation mean?
transmural - LARGER
What is the gold standard for dx MI?
troponin
Pt has “crushing” pain that radiates?
MI
What population has asymptomatic sx w/MI?
elderly
DM
women
Labs/imaging for MI?
EKG
troponin
When should troponin be high and normalize?
check q8hrs for 24hrs
doubles 5-8hrs then normalize 5-14days later
What to do if pt has non-ST elevation?
check troponin - if high –> MI
What other lab can be used for MI?
CK MB
Tx for MI?
1) admit + IV + O2 + morphine
2) ASA + Beta Blocker + Nitrates + ACE-I + statins + LMWH
3) +/- CABG/stent/angioplasty/tPA (Alteplase)
Meds for discharge-MI?
ASA
Beta Blocker
ACE-I
Statins
What drug should be avoided in stable angina but used in unstable and MI?
LMWH - enoxaparin
When can tPA be used (time)?
w/in 12 hrs
When should you NEVER use tPA?
head injury
bleeding (internal)
stroke
surgery
Pt has orthopnea and paroxysmal nocturnal dyspnea and diaphoresis?
lef sided CHF
What is left sided CHF?
fluid backs up into the lungs
What is the biggest cx of CHF?
HTN
What is the pathophys behind CHF?
CO is too low –> renin-angiotensin-aldosterone is activated –> increase in preload
What are 2 types of CHF?
systolic - problem squeezing
diastolic - problem filling
What is happening in systolic CHF?
cardiomyopathy - too big and won’t squeeze effectively
Pt has orthopnea and paroxysmal nocturnal dyspnea and diaphoresis -what to expect on PE?
dullness on percussion rales S3 gallop displaced PMI rales
What is happening in diastolic CHF?
myocardial hypertrophy - too much muscle and will not fill all the way but squeezing is fine
What are the NYAH classifications?
I - only w/ aggressive activity
II - climbing stairs; little limitation
III - daily activities are affected; mod limitation
IV - sx at rest; BAD
Pt has pitting edema, JVD, ascities?
right sided CHF
What test/labs to order for CHF?
CXR EKG cardiac enzymes - r/o MI CBC - r/o anemia (can cx CHF) echocardiogram - first line and gold standard bnp
What to see on CXR - CHF?
cardiomegaly
Kerle B lines
Tx for CHF-systolic?
mild/I-II -first line: ACE-I \+/-diuretic mod/II-III -ACE-I + diuretic + Beta blocker severe/III-IV -ACE-I + diuretic + Beta blocker + digoxin
Discharge drugs for CHF systolic?
ACE-I
beta-blockers
What to use if pt cannot use ACE-I?
ARB
What drugs are CONTRAINDICATED in CHF pts?
metformin
NSAIDs
Tx for diastolic CHF?
lifestyle changes beta-blockers diuretics digoxin \+/-ACE-I
Pt comes in with S3 + S4, dyspnea, pitting edema?
dilated cardiomyopathy
Cx of cardiomyoptahy?
idiopathic
CAD
How to dx dilated cardiomyopathy?
CXR - cardiomegaly, Kerley B lines , pleural effusion
echocardiogram - gold standard - dilated chamber
How to tx dilated cardiomyopathy?
admit + nitrate + O2 + B blockers + diuretics + ACE-I/ARB
ASA at discharge
Pt suddenly drops dead - literally?
dilated cardiomyopathy
most likely hypertrophic cardiomyopathy
Is hypertrophic cardiomyopathy genetic?
yes - autosomal dominant
YOUNG pt has chest pain on exertion, syncope, and palpitations?
hypertrophic cardiomyopathy
What is the pathophys of hypertrophic cardiomyopathy?
diastolic problem - overworks during exercise causing increase in HR + contractility
How to dx hypertrophic cardiomyopathy?
echocardiogram
family hx
How to tx hypertrophic cardiomyopathy?
AVOID STRENUOUS EXERCISE
B blocker - first line
CCB if B blocker doesnt work
+/- diuretics
Young male w/ lyme dz + fatigue, fever, chest pain, pericarditis?
myocarditis
How to tx myocarditis?
supportive - usually viral infxn
How to monitor myocarditis?
cardiac enzymes - troponin
Pt has postviral illness + chest pain when breathing?
acute pericarditis
Complications of acute pericarditis?
pericardial effusion
cardiac tamponade
Other cx of acute peridicitis?
acute MI OR after MI usually viral (coxsackivirus, EBV, influenza) or bacterial (TB)
Pt has chest pain, pericardial friction rub, what to expect on EKG?
diffuse ST elevation + PR depression
Pt has acute pericarditis - what temporarily relieves pain? What would you hear on PE?
leaning forward
pericardial friction rub
How to tx acute pericarditis?
self limiting
NSAIDs
Pt has ascities + hepatomegaly + distended neck veins?
cirrhosis
constrictive pericarditis
Pathophys of constrictive pericarditis?
pericarditis becomes very fibrous and scarred –> causes diastolic dsyfxn
Cx of constrictive pericarditis?
idiopathic
TB
Pt has muffled heart sounds, dullness at LEFT lung base, soft PMI?
pericardial effusion
Pt is SICK, JVD, ascities, and dependent edema?
constrictive pericarditis
How to dx constrictive pericarditis?
echocardiogram - increased pericardial thickness
CT/MRI - increased pericardial thickness
Tx of constrictive pericarditis?
+/- diuretics
tx underlying cx
What can pericardial effusion lead to?
cardiac tamponade
Cause of acute pericarditis?
pericardial effusion
How to dx pericardial effusion?
echocardiogram - first line
CXR - silhouette; water bottle sign
How to tx pericardial effusion?
depends on pt’s current status
pericardiocentesis is NOT indicated
Pt has stab wound on chest?
cardiac tamponade
What is an iatrogenic cause of cadiac tamponade?
central line
pacemaker placement
pericardiocentesis
What is important to know about cardiac tamponade?
how FAST fluid is getting in NOT how MUCH
Pathophys of cardiac tamponade?
too much fluid on the OUTSIDE of the heart –> problems with filling (diastolic dysfxn)
What is the beck’s triad?
hypotensive
muffled heart sounds
JVD
what is pulses paradoxus?
late decrease of arterial pressure when breathing in
How to dx cardiac tamponade?
echocardiogram - diagnostic
CXR - silhouette; CLEAR LUNGS
How to tx if cardiac tamponade is NOT hemorrhagic and pt is stable?
observe with echocardiograms and CXR
How to tx if pt is unstable but non hemorrhagic cardaic tamponade?
pericadriocentesis
What can mitral stenosis eventually lead to?
pulmonary HTN
right ventricular failure
How to diagnose mitral stenosis?
echocardiogram - diagnostic: big left atrium, thick mitral valve
CXR: large left atrium
How to tx mitral stenosis?
mild: diuretics and B blockers
mod to severe: surgery - percutaneous balloon valvuloplasty
a fib: anticoagulant + warfarin
Cx of mitral stenosis?
rheumatic fever
What is the cx of aortic stenosis?
age
rheumatic fever
congenital
What haps to the heart during aortic stenosis?
the left ventricle gets overworked –> big
Sx of aortic stenosis?
angina
syncope
HF sx: dyspnea
How to dx aortic stenosis?
echocardiogram - diagnostic: big LV and LA; aortic valve is calcified
CXR: calcified valve is late finding
cardiac cath: DEFINITIVE dx test: can exactly measure the valve
Tx of aortic stenosis?
valve replacement
What is the sx timeline for aortic stenosis and aortic regurgitaiton?
angina –> syncope –> HF
Pathophys of aortic regurgitation?
the leaflet valve is not closing all the way so blood is getting leaked back into heart –> LV pushes harder –> overworked –> big
What are cx for ACUTE aortic regurgitation?
infective endocarditis
trauma
aortic dissection
What are cxs for CHRONIC aortic regurgitation?
valvular - rheumatic fever, bicuspid aortic valve, MARFAN
aortic - osteogenesis imperfecta, aortic dissection, reiter’s sx, HTN
What are special PE for aortic regurgitation?
de musset sign - head bobbing
WIDENING PULSE PRESSURE: increased systolic w/ decreasing diastolic
water hammering pulse/ Corrigan’s
How to dx aortic regurgitation?
CXR - big LV
echocardiogram - big LV
cardiac cath - determine valve damage
How to tx aortic regurgitation?
surgery is definitive (replacement)
mild- observe w/ VASODILATORS, ACE-I/ARB
Endocarditis can cause what to the valves?
aortic regurgitaiton
mitral regurgitation
What can rheumatic fever cause to the valve?
mitral stenosis
aortic regurgitation
mitral regurgitation
rheumatic heart dz
What can Marfan sx cause to the valve?
aortic regurgitation
mitral regurgitation
mitral valve prolapse
Dilated LV on CXR/echocardiogram?
mitral stenosis
aortic stenosis
aortic regurgitation
mitral regurgitation
How to tx mitral regurgitation?
vasodilators + surgery
Pulsatile liver?
tricuspid valve regurgitation
Who are at high risk for tricuspid regurgitation?
IV drug users
How to dx tricuspid regurgitation?
echocardiogram only
How to tx tricuspid regurgitation?
diuretics (B blockers, ARB-I)
valve REPLACEMENT IS RARE -just fix the valve
Hypertrophic cadriomyopathy increase/decrease with squatting/valsalva?
increase
How to dx mitral valve prolapse?
echocardiogram only
How to tx mitral valve prolapse?
asymptomatic - nothing
chest pain - beta blocker
surgery is NOT required
Pathophys of rheumatic heart dz?
complication of strep A
occurs after rheumatic fever
How to dx rheumatic fever?
2 major or 1 major + 2 minor
major: polyarthritis, erythmema marginatum, cardiac probs, chorea, subcutaneous nodules
minor: fever, increase ESR, polyarthritis, hx of rheumatic fever, prolonged PR, hx of strep infxn
Tx of rheumatic heart dz?
tx strep from the start w/PCN or erythromycin
rheumatic fever tx w/ NSAIDs
Pt has new heart murmur + fever?
infective endocarditis
What are the two types of endocarditis?
acute and subacute
Bug for acute endocarditis (nosocomial)? What kind of valve?
s aureus
NORMAL VALVE
Bug for subacute (community)? What kind of valve?
strep viridans, enterococcus
on DAMAGED valves
IV drug users are at high risk for?
tricuspid regurgitation
endocarditis
Tx for endocarditis?
culture to find out which abx to use
What is the duke criteria used for?
endocarditis
Wide fixed splitting of S2?
atrial septal defec
What is hap to the heart w/ ASD?
right heart is working hard –> RV gets big
Sx of ASD?
if mild may be asymptomatic for life
if not, 40yo start to feel sx similar to stable angina
Right bundle branch block on EKG?
ASD
What complication can occur 40yo+ w/ ASD?
pulmonary HTN
Tx for ASD?
nothing unless pt is symptomatic (surgery)
What sx for VSD?
if PVR (pulmonary vascular resistance) is 0 = CHF, lower respiratory infxn if PVR is high = chest pain, dyspnea
How to dx VSD?
Echocardiogram
How to tx VSD?
if small - nothing
if big - surgery
Who are at risk for coarctation of aorta?
turner sx
What are sx of coarctation of aorta?
delayed femoral pulses compared to radial
cold extremities
HA
leg fatigue
What dx coarctation of aorta?
CXR-notching of the ribs and “3”
Tx of coarctation of aorta?
surgery
Machine like murmur?
patent ductus arteriosus
Who are at high risk for PDA?
premature babies
What can kill pts with PDA?
HF and infective endocarditis
How to dx PDA?
echocardiogram
How to tx PDA?
surgery unless SEVERE PULMONARY HTN -> surgery is contraindicated
What keeps PDA open? close?
open: prostaglandins
closed: indomethacin
in newborns - use prostaglandins until hand off
What is tetralogy of fallot?
VSD
right ventricular hypertrophy
pulmonary artery stenosis
overriding aorta
Crescendo-decrescendo at left upper sternal border?
tetralogy of fallot
What is a tet spell? What is the most common sx?
when pt squats to increase SVR
cyanotic
What is used to dx tetralogy of fallot?
echocardiogram
What is found on CXR w/ tetralogy of fallot?
boot shaped heart
How to tx tetralogy of fallot?
surgery
What organs should be inspected with hypertensive emergency and what will hap to those organs?
eyes: papilledema CNS: altered mental status kidneys: renal failure heart: unstable angina, MI, CHF lungs: pulmonary edema (CHF)
What could hypertensive emergency lead to?
posterior reversible encephalopathy syndrome
Pt has severe HA + HTN - steps to do?
1) lower Bp w/ hydralazine
2) CT scan to r/o bleeding
3) CT is neg –> LP
Pt has HA + visual disturbances + altered mental status?
hypertensive emergency
Pt has tearing/ripping/stabbing pain in chest, acute?
MI
aortic dissection
What to do when differentiating MI and aortic dissection?
EKG - MI –> may be non stemi –> cardiac enzymes
CXR - aortic dissection –> WIDENING MEDIASTINUM
What two areas can pt have pain for aortic dissection?
ascending - front
descending - back
What is dx for aortic dissection?
CXR- can be used to r/o MI
TEE
CT/MRI
How to tx aortic dissection?
MEDICAL EMERGENCY
type A (ascending) - SURGERY
type b (descending) - medicine (B blocker) + morphine
NO TPA
Pt has cullen sign?
ecchymoses around umbilicus
about to rupture AAA
What is the triad of ruptured AAA?
abdominal pain
hypotension
pulsatile abdominal mass
Who are at high risk for AAA?
Marfan sx
How to dx AAA?
US
CT
How to tx AAA?
surgery
Pt has leg off the end of the bed and foot feels better?
peripheral vascular disease
What are other PE for dangerous peripheral vascular disease?
no hair
thick toenails
decreased skin temp
no pulses
Which peripheral vascular disease has good prognosis? Why?
intermittent claudication
pain goes away w/ rest
Where does the pain occur the most in peripheral disease? Why?
distal metatarsals b/c it has the smallest arteries
Highest RF for peripheral disease? Most people have what as cx?
smoking
underlying cardio prob - CHF, CAD
What is normal ABI? What is bad ABI?
- 9-1.3
1. 3 - severe dz
What is the gold standard for peripheral disease?
arteriography
Who has the highest risk for peripheral disease?
DM
Tx for peripheral dz?
lifestyle changes PDE inhibitor (vasodilator) surgery -angioplasty, bypass IF pt has pain w/ rest and affects life activties
Where it is likely for a clot to occur in LE?
femoral artery
What are the 6 P’s for acute arterial occlusion? What else can this be used for?
Pain Pallor Pulseless Paresthesias Paralysis Polar (Cold) can also be used for compartment sx
Tx for acute arterial occlusion?
anticoags
surgery
What is the virchow triad?
injury to vessel
stasis
hypercoagulability
Pt has swollen leg after taking OCP?
DVT
First line imaging for DVT?
doppler
If doppler is positive for DVT - next step?
anitcoagulation
How to tx and manage DVT?
heparin bolus then warfarin
manage w/ PTT and INR
If pt has right sided CHF + DVT - how to tx?
tpa
Hx of DVT can cause…?
destruction of valves
does not allow blood to pass from superficial to deep
What does hx of DVT lead to?
ambulatory venous HTN –> edema d/t increase interstitial fluid accumulation –> weeping of skin –> brown color of the skin
How to tx chronic venous insufficiency? Complications? and how to tx complications?
stockings
avoid long standing time
elevate leg
ulcers can occur - dressing/unna boot
Pt has hypotension. oliguria, tachycardia, and altered mental status?
shock!
Pt has fever? Type of shock?
septic
Pt has trauma, GI bleeding, vomiting/diarrhea? Type of shock?
hypovolemic shock
Pt has leg swelling and skin color changes but relieved when leg is elevated?
chronic venous insufficiency
Pt has JVD? Type of shock?
cardiogenic
Pt has MI, angina, heart disease? Type of shock?
cardiogenic
Pt has spinal cord injury? Type of shock?
neurogenic shock
What is the first step to tx shock?
fluids-make sure pt is hemodynamically stable
vasopressors (dopamine/norepinepherine)
What to keep in mind for cardiogenic shock pts when tx?
fluids can overexert the heart –> use diuretics if LV is too high
What are some causes for hypovolemic shock?
hemorrhage - trauma
nonhemorrhagic- severe dehydration
What is pre HTN?
120/80+
What is stage I and stage II HTN?
> 140/90 and >160-/100
What is OK for 80yo - HTN?
150
What is HTN ER?
220/125
What is malignant HTN?
HTN + sx
How to tx stage I HTN? stage II?
over 60yo: CCB/ diuretic + ACE/ARB
younger 60: ACE/ARB + CCB/diuretic
ATP III - cholesterol: norm, borderline, high?
norm: 200
borderline: 240
high: 240+
ATP III - LDL: norm, borderline, high, very high?
norm: 130
borderline 160
high 190
very high 190+
ATP III - HDL: low, high?
low: less than 40
high: more than 60
ATP IIII - triglyceride: norm, borderline, high, very high?
norm: 150
borderline: 200
high: 500
very high: 500+
ATP IV - mod statin?
clinical ASVCD + 75yo OR cannot use high statin
LDL is lower than 190 + DM1/2+40-75yo
7.5% ASCVD + 40-75yo
ATPIV - severe statin?
clinical ASVCD + less than 75yo
LDL greater than 190
LDL less than 190 + 7.5% ASCVD + DM1/2
Dressler’s sx?
low grade fever + pleuretic chest pain + pericardial effusion AFTER injury to heart (2wks post MI)