Neuro - Auditory System Flashcards
What are the 3 parts of the ear?
Outer
Middle
Inner
Where is the ear organ located?
In the petrous part of the temporal bone - the hardest bone in the body
What makes up the outer ear
The pinna and the ear canal
What are the functions of the outer ear
Capture sound and focus it on the tympanic membrane
Amplify some frequencies by resonance in the canal
Protect the ear from external threats
How does the outer ear protect from external threats
Hairs in the canal
Wax provides physical barrier and also pH of wax kills things coming into the ear
What is the function of the middle ear
Amplification of sound
What makes up the middle ear
Tympanic membrane
3 ossicles with their associated muscles, tendons and ligaments
How does the middle ear amplify sound
Focuses vibrations from large surface area onto the smaller oval window to increase pressure
Uses leverage from the incus-stapes joint to increase the force on the oval window
What makes up the inner ear
Cochlea
What is the function of the inner ear
transduce vibrations into nervous impulses and also provide a frequency and intensity analysis of sound
What are the 3 cochlea compartments
Scala vestibuli
Scala media
Scala tympani
What is perilymph
Fluid found in the scala vestibuli and tympani which is high in sodium
What is endolymph
Fluid found in the scala media high in potassium
Where is the organ of Corti located
In the basilar membrane of the scala media
How is the Basilar membrane organised
Tonotopically - there s a narrow and tight base with a wide and loose apex
What frequencies cause vibrations in the base of the Basilar membrane
High frequency
What frequencies cause vibrations in the apex of the basilar membrane
Low frequency
What makes up the organ of Corti
Thousands of hair cells (both IHC and OHC)
What is the tectorial membrane
Located above the hair cells and allow deflection of hair cells to cause cell depolarisation
What cells are in constant contact with the organ of Corti
OHC
What nerves do IHC mainly carry
95% afferent fibres of the auditory nerve
What nerves do OHC mainly carry
95% efferent fibres of the auditory nerve
What is the function of afferent auditory nerves
Transduction of sound into nerve impulses
What is the function of efferent auditory nerves
Modulation of the sensitivity of the response (active amplifying of the OHC)
What are the hairs of hair cells called
Stereocilia
What does stereocilia deflection lead to
Deflection towards the longest cilium causes the opening of K channels and thus depolarisation
Explain the process of transduction
Vibrations cause the IHC to contact the tectorial membrane and thus their stereo cilia deflect and K channels are opened. There is influx of K into the cell and thus depolarisation, leading to the opening of voltage gated calcium channels.
These channels open and therefore calcium causes the exocytosis of glutamate out of the fair cells and thus a nervous response in propagated through the afferents of the auditory nerve
Describe the pathway of auditory information from the cochlea to the cerebral hemisphere
Spiral ganglions from the cochlea extend to the cochlear nucleus.
Auditory information then reaches the superior olive and crosses contralaterally (some fibres stay ipsilateral).
Fibres then travel to the inferior colliculus in the brainstem and then to the medial geniculate body in the thalamus. Finally fibres reach the auditory cortex in the cerebral hemisphere.
What is the need for tonotopic arrangement of hearing
If we can’t discriminate different frequencies then we cannot discriminate or interpret speech
What is frequency
Cycles per second, perceived tone
Pitch