Neuro Anatomy 1 - CNS Overview Flashcards
How many spinal nerves are there?
31
What is the name of the embryonic structure from which the brain and spinal cord develop from?
Neural tube
In embryology, at 4 weeks, how many swellings (primary vesicles) does the neural tube have? What are their names?
3 - prosencephalon, mesencephalon, rhombencephalon
In embryology, at 6-8 weeks, how many swellings (secondary vesicles) are there? What are their names?
5: Telencephalon and diencephalon (from prosencephalon) Mesencephalon (same as at 4 weeks) Metencephalon and mylencephalon (from rhombencephalon)
What part of the mature brain does the telencephalon form?
Cerebral hemispheres
What part of the mature brain does the diencephalon form?
Thalamus, hypothalamus
What part of the mature brain does the mesencephalon form?
Midbrain
What part of the mature brain does the metencephalon for?
Pons, cerebellum
What part of the mature brain does the myelencephalon form?
Medulla oblongata
What are the 3 parts of the brainstem?
Midbrain Pons Medulla oblongata
What is the name for the combined thalamus and hypothalamus?
Diencephalon
What is continuous inferiorly with the medulla oblongata?
Spinal cord
What are the 2 principle groups of cells of the CNS?
Neurones Glial cells
Are most neurones in the CNS unipolar or multipolar?
Multipolar
What type of cells in the CNS act as communicators, receiving information (chiefly via synapses), integrating the information and then transmitting electrical impulses?
Neurons
What is another name for a neurons cell body?
Soma
What is the name for the part of the cell body of a neuron that connects to the axon?
Axon hillock
Name a type of neurone that has no true dendrites?
Primary sensory neurone of spinal ganglion
Name a type of neurone that has no axon?
Amacrine cell of retina
What is the role of glial cells?
To support and provide insulation between neurones
Are neurones or glial cells more numerous?
Glial cells
What are the 4 major types of glial cells?
Astrocytes Oligodendrocytes Microglia Ependymal cells
What shape are astrocytes?
Star-shaped (name comes from astro- e.g. astronaut) - has many numerous processes
Is there connective tissue in the CNS?
No
What is the role of astrocytes? (3)
Roles in support, maintaining blood-brain barrier, environmental homeostasis
What type of cell produces myelin in the CNS?
Oligodendrocytes
What type of cells produce myelin in the PNS?
Schwann cells
What is myelin formed from?
Wraps of cell membrane doubled up
What is the name of the gaps of myelin sheath which exposes part of a neurones axon?
Node of Ranvier
What is the purpose of myelin?
To speed up conduction
What is the function of microglia?
Immune monitoring and antigenpresentation
What is the origin of microglia?
Hemopoietic - similar lineage to macrophages
What happens to microglia when they are activated e.g. by a bacterial infection?
They pull in their short branches and become rounder, taking on a similar appearance to a macrophage
What is the name of the cells that line the ventricles?
Ependymal cells
What type of epithelium do ependymal cells form?
Ciliated cuboidal/ columnar epithelium
Do the ependymal cells of the ventricles form a good barrier between the CSF and brain tissue?
No