Neuro

Question 1

What’s the name for slurred speech?

Answer 1

Dysarthria

Question 2

Motor neurones presentation

Answer 2

Degenerative condition of anterior horn cells and UMN in SC resulting in mixed upper and lower motor neurone signs

Question 3

Types of MND

Answer 3

Amyotrophic lateral sclerosis

Question 4

Amyotrophic lateral sclerosis

Answer 4

Usually one limb affected more than th eother

Faasciulations, brisk reflexes, extensor plantars

UMN & LMN problems

Question 5

Bulbar MND

Answer 5

Dysarthria, tongue wasting, fasciculation, brisk jaw jerk

Question 6

Bulbar vs pseudobulbar

Answer 6

Bulbar - lower motor neuron features, absent features

pseduobulbar - exagerated gag reflex

Question 7

Treatment for NMD

Answer 7

NO cure

Riluzole

Question 8

Riluzole MOA

Answer 8

Glutamate antagonist

Question 9

MS pathophysiology

Answer 9

T cells trigger attack on myelin, leading to scarring, plaques

Question 10

Rx for MS

Answer 10

Low vit D 
EBV exposure
Smoking
Extremes of latitude
Obesity in adolescents

Question 11

Symptoms of MS

Answer 11

Optic neuritis
Double vision
Sesnsory disturbance (like transverse myelitis)
Balance problems
Altered sensation travelling down back when bending neck forward (Lhermitte’s syndrome)