neuro Flashcards
1
Q
Valproate (Depakote)
A
Valproate is an antiepileptic drug (AED) that acts by blocking sodium channels. Valproate is recommended as the first-line treatment of choice for most patients with initial onset JME. It is a broad spectrum antiseizure medication that controls all three seizure types in JME, and has the best established efficacy in JME. Although commonly used, valproate has a number of side effects, including weight gain, hair loss, tremors, GI symptoms, and hepatotoxicity.
2
Q
Juvenile myoclonic epilepsy (JME)
A
Juvenile myoclonic epilepsy (JME) is a common type of generalized epilepsy that typically begins in adolescence, characterized by myoclonic jerks, generalized tonic-clonic seizures, and sometimes absence seizures.
