Neuro Flashcards
Extradural (middle meningeal)
Subdural (bridging vein)
what type of bleed has loss of consciousness (typically immediately after a head injury) followed by a period of lucidity
Extradural
Sub arach
When is endarterectoy indicated
stroke/TIA
+
mod/severe stenosis on USS (>50% stenosed)
TACI has which of:
1. unilateral hemiparesis and/or hemisensory loss of the face, arm & leg
2. homonymous hemianopia
3. higher cognitive dysfunction e.g. dysphasia
All 3
PACI has which of:
1. unilateral hemiparesis and/or hemisensory loss of the face, arm & leg
2. homonymous hemianopia
3. higher cognitive dysfunction e.g. dysphasia
2 of them
LACI has what presentation (lacunar infarct)
presents with 1 of the following:
1. unilateral weakness (and/or sensory deficit) of face and arm, arm and leg or all three.
2. pure sensory stroke.
3. ataxic hemiparesis
POCI presents with
presents with 1 of the following:
1. cerebellar or brainstem syndromes
2. loss of consciousness
3. isolated homonymous hemianopia
How long is the thrombolysis window
4.5 hours
how long to avoid driving after a stroke
at least a month
what is ROSIER for
stroke mimics
Mx of a TIA
300mg aspirin if no CI and 24h review in TIA clinic (if it happened in the last 7 days, if >7 days then 7 days until clinic)
If they already take low dose aspirin then just continue that until specialist review.
Specialist will prob start clopi and high dose statin, plus MRI and carotid USS
Brocas aphasia description and what lobe of brain?
Comprehension normal but speech impaired, frontal lobe
Wernickes aphasia description and what lobe of brain?
Fluent speech but poor comprehension. Temporal lobe (near ears)
What is malignant MCA sydrome
cerebral oedema following MCA stroke
type of headache worsened by physical activity
migraine
Seizure where still aware but have focal motor/sensory/autonomic sx, no post ictal
simple focal
seizure where awareness impaired, have focal motor/sensory/autonomic sx, post ictal confusion
complex focal eg TLE
seizure that begins focally but then becomes convulsive generally
secondary generalised (still a type of focal)
seizure with sudden jerk of limb
myoclonic (generalised)
seizure with sudden loss of muscle tone, ‘drop attacks’
atonic (generalised)
seizure of baby <1 with clusters of sudden tonic flexion
infantile spasms (generalised)
generalised seizure generally first line
valproate
focal seizure generally first line
carbamaz/lamotrigine
Kernigs and brudzinskis which is which
kernigs legs
brudz- neck
Benpen doses for stat IM in meningococcal meningitis in the community
<1y 300mg
1-9y 600mg
>10y and adult 1200mg
Central venous thrombosis rx
thrombolysis and long term warfarin
Neck pain, ataxic gait, UMN signs in legs
cervical spondylitic myleopathy
cervical spondylitic myleopathy rx
surgical decompression
Weakness and sensory deficit developing over more than 8 weeks
CSF shows high protein and low leukocytes
Chronic inflammatory demyelinating polyneuropathy
Cluster headache rx
100% O2
SC triptan
verapamil for prophylaxis
bilat intention tremor that is relieved by alcohol
essential tremor
mx options for essential tremor
propranolol or primidone could reduce it
What classically precedes GBS
campylobacter
What is the neurology in GBS
ascending weakness of all 4 limbs but proximal before distal
No sensory features
Areflexia
headaches, visual disturbances and pulsatile tinnitus
Idiopathic IC HTN
IICH rx
weight loss
acetazolomide if visual loss on presentation
Upper and lower motor neuron signs
No sensory features
Fasciculations
Motor neurone
MND rx
riluzole can prolong life in AML
BIPAP at night
3 types of MS
relapsing remitting - can progress to secondary progressive
primary progressive
Rx acute MS relapse
steroids (reduces length of flare only)
General MS rx
DMARDs
or symptomatic
Rx for fatigue in MS
amantidine
Rx of spacisity in MS
baclofen/gabapentin
Rx of bladder dysfunction in MS
intermittent self catheterisation
Anticholinergics
Rx visual field oscillations in MS
gabapentin
Urinary incontinence
Erectile dysfunction
Parkinsonism
REM sleep disorder
Multi system atrophy
Severe unilateral headache associated with lacrimation that completely resolves with indomethacin
Paroxysmal hemicrania
Fluctuating muscle weakness that is worse on repetitive movements and improves with rest
myaesthenia gravis
MG rx
AChEi
Immune suppression
Plasma exchange/IVIg
Thymectomy
What nerve is damaged:
motor: paralysis of knee flexion and all movements below knee
sensory: loss below knee
reflexes: ankle + plantar lost, knee jerk intact
Sciatic (L4-S3)
Horizontal diploplia nerve
CN6 (Lateral rectus 6- lateral like horizontal)
Vertical diploplia nerve
CN4 (contralateral side as it crosses, superior oblique- superior like vertical)
Mx acute ischaemic stroke of proximal anterior circulation who present within 4.5 hours
thrombolysis AND thrombectomy
triptans are c/i in hx of
IHD
migraine prophylaxis
propranolol or topiramate (propran in childbearing age woman)
Acute migraine treatment
triptan (nasal in teens)
second line: metoclopramide or prochlorperazine
Confusion, gait ataxia, nystagmus + ophthalmoplegia
wernickes
the homonymous hemianopia and the paresis are always on the same or different sides
same side
Bitemporal hemianopia, upper quadrant defect
pituitary tumour
Bitemporal hemianopia, lower quadrant defect
craniopharyngioma
tuberous sclerosis- benign tumours can be in brain, can cause epilepsy
eponymous sign: multiple sclerosis complains of tingling in her hands which comes on when she flexes her neck
Lhermittes
Dysphagia plus eye weakness/ptosis =?
Myaesthenia Gravis
Encephalitis symptoms with bilat temporal lobe changes on CT suggests
Herpes simplex encephalitis
Autoimmune encephalitis is typically the result of ..?
A paraneoplastic syndrome (usually secondary to small cell lung cancer or ovarian teratoma)
Cryptococcal meningoencephalitis typically affects what demographic?
Those with severe immunodeficiency (especially AIDS).
It has a subacute presentation, with symptoms progressing over several weeks (as opposed to a few days).
CMV encephalitis typically affects?
almost always occurs in patients with severe immunodeficiency. In those with HIV, it typically occurs once the CD4 count is <50.
first line AEDs for diff types of epilepsy
Give sodium valproate for all unless your female (preg/repoductive age) or they’re focal.
Lamotrigine/Levetriacitem otherwise
Ethosuximide for absence (avoid CBZ)
After stroke if aspirin and clopi c/i what to give
MR dipyridamole