Neuro 1 Flashcards

1
Q

Brain and spinal cord is which system

A

CNS central nervous system

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2
Q

peripheral nerves and ganglia system name?

A

PNS peripheral nervous system

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3
Q

Functional unit of the nervous system

A

neuron

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4
Q

3 functions of neurons:

A
  1. Conduct “electrical” signals - action potentials
  2. Release “chemical” signals - neurotransmitters
  3. integrate neuronal activity and connections “circuitry”
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5
Q

What are the 3 types of neurons corresponding to their functions?

A
  1. Motor nerves: control mvt
  2. Sensory nerves: detect external stimuli
  3. Association neurons: in CNS responsible for behaviour, thought, emotions …
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6
Q

Dendrites:

A

part of the neuron that RECEIVES info from sensory receptors and sends it to the cell body

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7
Q

Axons:

A

DELIVER electrical signal from cell body TO another neuron / effector organ

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8
Q

A neuron performs the function of moving “_____” rapidly by conducting _____ ______ called action potentials frm one physical location to another, then converting the electrical impulse to _______ _____ at the _____

A
  • information
  • electrical impulse
  • chemical signal
  • synapse
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9
Q

Sensory or Afferent neurons conduct impulses from ______ into ______

A

Sensory receptors (PNS/CNS)
into
CNS
(carry signals TO cns)

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10
Q

_______ are located entirely within the CNS and help integrate CNS functions.

A

Association or interneurons

- sends signals from one neuron to another

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11
Q

Motor or Efferent neurons conduct impulses from ____ out of the _____ to _____

A

sensory receptors (CNS/PNS)
out of the CNS
to effector organs like muscles or glands (PNS)
(carry signals FROM cns)

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12
Q

What type of neuron has reflex and voluntary control of skeletal muscles?

A

somatic motor neurons

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13
Q

What type of neuron has involuntary control of smooth muscle, cardiac muscle, and glands?

A

autonomic motor neurons

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14
Q

What type of neuron is further subdivided as sympathetic and parasympathetic?

A

autonomic neurons

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15
Q

What are 4 types of neurons corresponding to their structure?

A
  1. pseudopolar (unipolar): sensory, 1 process that splits
  2. bipolar: retinal and chochlear, 2 processes
  3. multipolar: most common, motor association, many dendrites but one axon
  4. anaxonic: some CNS neurons, no obvious axon
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16
Q

What are 2 supporting cells of the PNS?

A
  1. Schwann cells: form myelin sheaths around PNS axon

2. Satellite cells: support cell bodies with ganglia of PNS

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17
Q

What are 4 supporting cells of the CNS?

A
  1. oligodendrocytes: form myelin sheaths around CNS axon
  2. microglia: migrate through CNS and phagoytose debris
  3. astrocyte: regulate external environment
  4. ependymal cells: line ventrical cavities of brain and spinal cord
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18
Q

Schwann cells of the PNS are similar to ____ of the CNS.

How are they different?

A

oligodendrocytes
PNS: Schwann cell wraps one axon
CNS: One oligodendrocyte forms myelin sheaths around several axons

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19
Q

Astrocytes are ____ cells.

A
Glial cells (insulate and support)
- most abundant nervous tissue in the brain
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20
Q

Processes of astrocytes 1/7.

A
  • K+ taken from ECF
  • diffused from neurons durig impulse
  • maintain proper ionic environment
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21
Q

Processes of astrocytes 2/7.

A
  • take up NT glutamate
  • convert to glutamine
  • release back to neuron
  • reform glutamate
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22
Q

Processes of astrocytes 3/7.

A
  • end feet surround blood capillaries
  • take up glucose
  • metabolize to lactate
  • use for energy (ATP) aerobic
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23
Q

Processes of astrocytes 4/7.

A
  • formation of synapses in CNS
24
Q

Processes of astrocytes 5/7.

A
  • regulate neurogenesis in adult brain

- stem cell diffferentiation (glial and neuronal)

25
Processes of astrocytes 6/7.
formation blood brain barrier
26
Processes of astrocytes 7/7.
- release NT | - stimulate/inhibit activity of neurons
27
What is the structure/function of the blood brain barrier?
- capillaries in the brain do NOT have pores between endothelial cells of the capillary walls - tight junctions - control what moves between blood plasma and the brain
28
What moves easily through the BBB?
- non polar mol: O2, CO2 | - organic mol: alcohol, barbituates (CNS depressants)
29
What type of brain cell aids the structure and function of the BBB?
- astrocytes influence structure and function (regulation)
30
Alcohol is a _____ _____ that directly affects brain cells. How so/what?
- CNS depressant - inhibits behaviour: animated, talkative, social - altered speech, slow rxn, foggy memory - related to genetics, dose, size, weight gender etc
31
Nicotine influence on brain?
- <10 sec to cross BBB - fits (lock/key) of Ach NT receptor - increases other NT like dopamine - increases other NT like: dopamine, norepinephrine, serotonin - increases other NT because other components decrease MAO enzyme activity
32
NO and NMDA with BBB?
acetominophin (tylenol) - inhibition of NO (NT) - receptors NMDA
33
Drugs to treat neurodegenerative disorders (can/cannot) pass through BBB!
cannot | i.e. parkinsons and alzheimers
34
What is the relation between treating rabies and the BBB?
- immediate treatment necessary - rabies (virus) runs in the blood stream and treat with immune cells/drugs/antibodies to fight - once it crosses the BBB immune cells and drugs cannot pass
35
Two divisions of the autonomic nervious system.
- somatic | - autonomic
36
Somatic nervous system sends signals from where to where?
- CNS (spinal cord) to effector skeletal muscle
37
How many neurons does it take to send signal from CNS to effector for somatic?
- one neuron
38
Somatic neurons are excitatory and/or inhibitor
excitatory only
39
Somatic neurons are fast/slow conducting?
fast conducting | - all myelinated
40
Autonomic motor nervous system involves which effector organs?
- cardiac muscle, smooth muscle, glands
41
How many neurons does it take to go from CNS to effector cell for autonomic?
- 2 neurons - preganglionic - post ganglionic (in between is the autonomic ganglion when the ends touch)
42
Autonomic motor neurons excitatory/inhibitory?
- excitatory or inhibitory
43
Autonomic motor neurons are slow/fast?
- slow conducting - preganglionic slightly myelinated but thin - post ganglionic fibres are not myelinated and thin
44
Two divisions of the autonomic nervous system?
- parasympathetic PSNS | - sympathetic SNS
45
Most organs receive input from both systems, but the response is ___
- opposing responses in effector organs of PSNS and SNS
46
Which organs of the autonomic nervous system do not have dual innervation?
- adrenal medulla - arrector pili muscles (hair stand) - sweat gland - most blood vessels
47
All preganglionic fibres of the autonomic system (PSNS and SNS) release what neurotransmitters?
- acetylcholine - therefore cholinergic nerves
48
What NT are released for post-synaptic nerves of the autonomic nervous system?
- ACh (cholinergic) for parasympathetic (rest and digest) | - NE / E (adrenergic) for sympathetic (fight or flight - adrenaline rush)
49
ACh and NE bind (same/different) receptors?
different
50
What is an example of a disease that causes autonomic nervous system dysfunction?
Lyme disease | a type of of dysautonomia
51
Bacteria of lyme diesease?
Spirochetes
52
How is lyme disease spread?
- tick bites | - bite at adult stage feed on humans
53
What causes the circular lesion of the skin?
- immune response in which neutrophils cannot get in (fail to appear)
54
Why can't neutrophils get in?
the saliva disrupts the immune response by preventing the neutrophils to get in - therefore spirochetes bacteria multiplies
55
Where can the bacteria spread to?
- bloodstream, joins, nervous system, skin far away from lesion
56
What is synesthesia?
- perceiving one sense simultaneously with an additional sense