Nervous System, Brain Overview & Brain Protection Flashcards

1
Q

What are Nerves?

A

Collection of cells (neurons) which provide anatomical links to the tissues and the brain and vice versa

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2
Q

What are the 2 Types of Neurones going to and from the Tissues?

A

Afferent - towards brain and Efferent - away from brain

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3
Q

2 Parts of the NS and what Nerves do they Split into?

A
  • CNS (brain and spinal cord)
  • Peripheral NS (everything else) these divide into spinal and cranial nerves
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4
Q

What does the Peripheral Nervous System Split into?

A

Somatic NS and the Autonomic NS

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5
Q

What are the Somatic NS and Autonomic NS responsible for?

A

Somatic - Controls skeletal muscle (conscious control)
Autonomic - Controls visceral (smooth) muscle, cardiac muscle, glands (unconscious control)

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6
Q

What does the Autonomic System Split into and what does it correspond to?

A

Sympathetic NS - fight/flight/freeze (speed up)
Parasympathetic NS - rest/digest/feed/breed (slow down)

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7
Q

In Terms of NT’s how is Addiction Initiated?

A
  • Synapses become overstimulated which damages neurones
  • This causes a failsafe to kick in which reduces the effect of NT’s
  • This reduces the threshold of how much NT it takes to reach a certain level of feeling. Tolerance has increased.
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8
Q

In terms of Stress how is Addiction Formed?

A
  • During stress, the hormone cortisol
  • Cortisol acts upon the pre-frontal cortex to help you manage situations
  • During chronic stress, the brain seeks for stress relievers
  • This increases dopamine release driving you to seek stress relief more and more
  • Cortisol also dampens the effect of serotonin, so we concentrate on the thing that’s stressful more
  • AAR dopamine leads you to seek reward while reduced serotonin means you won’t feel satisfied
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9
Q

Common NT’s (acetylcholine, dopamine, glutamine, serotonin)

A

Acetylcholine - Initiates movement to muscle fibres. Facilitates neuroplasticity (ability to change, modify and adapt across the cortex
Dopamine - Pleasure chemical that seeks for rewards and nice things eg adrenaline seeking
Glutamine - Excitement chemical, linked to memory and learning
Serotonin - Calming chemical that modulates mood and brings sense of satisfaction - deficiency leads to depression

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10
Q

Common NT’s (Norepinephrine, Gama-Aminobutyric Acid, Endorphins)

A

Norepinephrine - Hormone and NT linked to stress response, arousal, vigilance and memory
Gama-Aminobutyric Acid (GABA) - Inhibits neural signalling. Linked to learning. Too little = seizures
Endorphins - euphoria/wellbeing doing something you enjoy

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11
Q

What are the Brains Different Parts?

A
  • Brain Stem
  • Diencephalon
  • Cerbrum
  • Cerebellum
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12
Q

What are the Different Ventricles of the Brain? And Where are they?

A
  • Lateral Ventricle - (2) in each hemisphere
  • Third Ventricle - located in slit between thalamic halves
  • Fourth Ventricle - between brain stem/cerebellum
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13
Q

What Connects the two halves of the Brain?

A

White matter called Corpus Callosum

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14
Q

How does the Blood Brain Barrier Protect the Brain?

A
  • It has a selective barrier to allow nutrients to pass freely, stopping pathogens crossing. Allows hydrophobic (O2, CO2)
  • Separates bloodborne substances from neurones
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15
Q

What does the Cerebrospinal Fluid do?

A
  • Similar composition to plasma w/ less protein/different ion concs
  • Forms cushion layer supporting CNS organs
  • Prevents brain crushing under its own weight
  • Absorbs pressure impact to CNS from blows and other trauma
  • Nourishes brain/carries chemical signals throughout it
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16
Q

How is the Brain Protected?

A

By bone, meninges and cerebrospinal fluid (CSF). Harmful substances are shielded from the brain by the blood brain barrier.

17
Q

The Meninges Structure; What each Layer does

A
  • X3 Layers; Dura Mater, Arachnoid Mater and Pia Mater
  • Dura Mater - Outer layer, very hard to tear/extremely tough. Closely adhered to the skull
  • Arachnoid Mater - Between dura and Subarachnoid space. Bleeding in this area = subdural haematoma
  • Subarachnoid Space - Has CSF and large blood vessels. Vessel rupture called subarachnoid haematoma
  • Pia Mater - delicate connective tissue that clings to the brain
18
Q

What is the Blood Brain Barrier? When does it become Ineffective?

A

The protective mechanism helping maintain a stable environment for the brain.
Ineffective against substances that diffuse into the plasma and stress increases the ability of chemicals to pass through barrier

19
Q

What does the Brain Stem Split into?

A
  1. Medulla Oblongata
  2. Pons
  3. Midbrain (Diencephalon)
20
Q

What does the Diencephalon Consist of?

A

Thalamus, basal ganglia/nucleui, hypothalamus, pituitary gland and pineal gland

21
Q

What is the Cerebrum Split into? And its Anatomical Structure?

A
  • Has 2 halves and 4 lobes
  • 4 lobes; frontal, temporal, parietal, occipital
  • Convolutions (gyri) increase SA. Sulci form groves between gryi
  • Each lobe has distinct functions and are separated from each other by deep grooves called fissures