Nervous System Flashcards
What are the 3 basic fucntions of the nervous system
Sensory
Motor
Integration
What is the sensory function of the nervous system
Sensing changes from the internal or external environment and sending it to the spinal cord or brain
What is the integration function if the nervous system
Reviewing , analysing, and storing signals to integrate into a response
What is the motor function of the nervous system
The integrated response sent out to the body
What are neurons?
Aka nerve cells
The functional unit of nervous tissue
Transmits information throughout the nervous system
Monitors for changes, converts signals to impulses, send impulses to other neurons
What are neuroglia
Aka glia
Means “nerve glue”
Special nervous tissue that do not have axons
Substances that influence neuronal function are exchanged between extracellular space and neuroglial cells
Insulate, nourish, support and protects neurons
What are ganglion
Dense group of nerve-cell bodies in the PNS
What are the 3 basic parts of the neuron
Cell body
Dendrites
Axon
What is the cell body of a neuron
Inclused nucleus and cytoplasm and organelles
What are dendrites
Short, numerous highly branched processes that extend out from the cell body
What do dendrites do
Recieve impusles from other neurons or receptors that are stimulated by internal or external changes in the environment
Carry impulses TOWARDS the cell body
What are axons
A single process extending from the cell body
May be called a nerve fiber
What do axons do
Conduct impulses AWAY from the cell body to other cells
What are bundles of axons called in the CNS and outside of the CNS
Inside: Tracts
Outside: nerves
Axons are often myelinated, what are the myelinated cells called in the CNS and the PNS
CNS: oligodendrocytes
PNS: Schwann cells
What is myelin
An insulator that speeds the conduction of impusles along axons (white)
Nervous tissue that is myelinated is called
White matter
Nervous tissue that is not myelinated is called
Gray matter
Gray matter often contains
Cell bodies
White matter often contains
Myelinated axons
Sensory or afferent nerves
These affect the brain
These nerves conduct impulses from sensory receptors in the body TOWARDS the CNS
Motor or afferent nerves
Conduct nerve impusles AWAY from the CNS
these effect the body: control responses or skeletal maucle contraction
True or false
A nerve can be sensory, motor or both
True
What is the motor function of the somatic nervous system
Voluntary control of skeletal muscles (conscious movement)
What is the sensory fucntion of the somatic nervous system
Information that is consciously percieved (muscles, skin, eye, ear)
What is the function of the autonomic nervous system
Coordination of automatic (unconscious) body functions
Smooth and cardiac mucles, endocrine glands, heart rate, GI motility, homeostasis
True or false
Many fibers in the somatice nervous system are unmyelinated
FALSE
they are normally myelinated (rapid conduction)
True or false
Many fibers in the autonomic nervous system are unmulinated
TRUE
What is the autonomic nervous system divided into
Parasympathetic and sympathetic nervous system
The sodium potassium pump maintains a higher concentration of sodium ions ____ the membrane and a higher concentration of potassium ion ____ the membrane
Outside
Inside
True or false
The sodium potassium pump moves more sodium out than potassium enters
True
True or false
There is a negative charge on the outside of the cell
FLASE
There is a negative charge on the INSIDE of the cell
Why is the cell considered polarized
Because of the difference in charges across the membrane
The difference in electrical charge across the membrane is called the
Resting membrane potential
True or flase
The sodium potassium pump is closed at rest
True
What happens during depolarization
Upon stimulation, sodium channels open allowing sodium to diffuse into the cell, and the influx of positive ions changes the charge inside the cell from negative to positive
What happens during repolarization
Rapidly after depolarization, the sodium channels close and potassium channels open, potassium moves OUT of the cell to reestablish a positive charge outside the cell and a negative charge inside the cell which restores resting membrane potential
The whole process in changes of charge is called an
Action potential
What is the difference between repolarization and resting state of a cell
Sodium ion concentration are now higher inside the cell and potassium ion concentration are higher outside the cell
What restores a normal resting state of a cell after repolarization
Active transport by the sodium potassium pump
What is absolute refractory period
Time when the neuron will NOT respond to a stimuli no matter what
What is relative refractory period
At the end of repolarization (neuron is almost back to resting) when the neuron WILL respond to a stimuli that is stronger than normal
Why can nerve impulses not be conducted backwards
Because of the refractory period
What is threshold
The change in membrane potential required to cause adjacent membrane to depolarize
What is the all or nothing principle
Either the neuron depolarizes significantly enough to depolarize the adjacent neuron or it is not sufficeint enough to carry on the impulse and the signal dies out
If the stimulus is too weak to cause a wave of depolarization, what may you see
A localized contraction or response but will not spread
How does the body speed up transmission of impulses
Myelinated axons
How does myelin speed up transmission of impulses
Myelin insulates the axons and prevents sodium movement in the areas covered
Depolarization only occurs at the gaps between the myeline
What is the rapid conduction of impulses in myelinated axons called
Saltatory conduction
What are the gaps in the myelin called
Nodes of ranvier
What is multiple sclerosis
Disease caused by degeneration of myelin sheaths, inhibiting conduction of nerve impulses
Affects the ability to see and coordinate movement
Vitamin D helps prevent this
What is an electroencephalogram (EEG)
A recording device that measures and records brain waves, helps diagnose some disorders
How do Local anesthetics like lidocaine work
The block sodium channels of the neuron and prevent depolarization. Impulses cannot be sent to the brain and therefore give no pain signal
What are synapses
The junction between two neurons (or a neuron and a target cell) because they do not touch
The gap between two neurons is called the
Synaptic cleft
True or false
Neurons can have up to thousands of synapses
True
The presynaptic neuron releases a neurotransmitter that is recieved by the
Postsynaptic neuron
The synaptic bulb is the end of the
Presynaptic axon/neuron
The synaptic bulb contains
Mitochondria
Neurotransmitters in vesicles
What causes the synaptic bulb on the presynaptic neuron to release neurotransmitter vesicles into the synaptic cleft
When depolarization causes calcium channels to open
What are the two types of neurotransmitters and what do they do
Inhibitory: increases polarization (hyperpolarize) and makes it less likely to depolarize (prevents the sodium channels from opening)
Excitatory: causes depolarization
What is summation
The process of adding up the effect of multiple stimuli that are individually sub-threshold in order to reach threshold
The relative balance of excitatory and inhibitory neurotransmitters determines the overall effect on the
Postsynaptic membrane
What is a acetylcholine
Very common neurotransmitter
Can be excitatory (neuromuscular junctions)
Can be inhibitory (heart)
What are the 3 Catecholamine neurotransmitters
Norepinephrine
Epinephrine
Dopamine
Associated with arousal and fight or flight reactions in the sympathetic NS. Stress hormones
Norepinephrine
Fight or flight response
Epinephrine
Fight or flight response
Is also secreted by adrenal medulla as a hormone
Dopamine
In the brain, important for autonomic functions and muscular control
What is Gamma-aminobutyric acid
GABBA
inhibitory neurotransmitter in the brain
What is glycine
Inhibitory neurotransmitter in the spinal cord
Some tranquilizers affect GABBA receptors to increase its ____ effect in the brain
Inhibitory
How do amphetamines affect neurotransmitters
Increases catecholamine release like dopamine
Stimulant
Causes schizophrenic episodes
Methamphetamine
What do antipsychotic drugs do
Block dopamine
What does cocaine do to neurotransmitters
Prevents normal reuptake of norepinephrine at synaptic bulb end
Stimulant
What does lithium carbonate do to neurotransmitters
Decreases norepinephrine release
Used to treat mania: slows processes, stabilizes mood and depression and anxiety disorder in pets
What do opiates do to neurotransmitters (heroine)
Binds receptors normally used by endorphins
Provides analgesia, improves mood/emotions
Euphoric (high)
What does alcohol, barbituates, benzodiazepines do to neurotransmitters
All effect GABBA: either promoting or imitating its effects
Therefore it is inhibitory (because GABBA is inhibitory)
How do toxins affect neurotransmitters
Different toxins either mimic excitatory receptors and cause over stimulation or blocking receptors and preventing stimulation or normal function
What does strychnine (poison) do to neurotransmitters
Binds irreversibly to inhibitory receptors (inactivates them)
Blocks GABBA
Overstimulation of CNS motor fibers
See convulsions
How are neurotransmitters recycled and reused
After release from the presynaptic membrane and binding with postsynaptic receptors, enzymes break down the neurotransmitters to remove it from the receptor to end the stimulus
The break down products are reabsorbed by the presynaptic membrane and reassembled to be used again
What is acetycholine broken down by
Acetylcholinesterase
Monoamine oxidase (MAO) breaks down norepinephrine. Many antidepressents inhibit MAO, why?
By inhibiting MAO, they prolong the excitatory action of norepinephrine, relieving anxiety
By knowing the areas of the brain, what does this help you do
Understand neurological diseases and medications that affect the CNS
What is the cerebrum
The largest part of the brain responsible for “higher order” behaviour such as learning, intelligence and awareness, thought and perception of sensation
What does the cerebrum do
Recieves and interprets info
Initiates skeletal muscle movement
In charge of emotions, learning, memory and recall
What is the cerebrum divided by
The median fissure or groove
Into two hemispheres
True or false
Each hemisphere of the cerebrum is connected to the same side of the body
FALSE
they are connected to the contralateral or opposite side if the body
The outer part or the cerebral cortext is ___ matter containing ____
Gray
Cell bodies
The inner part of the cerebrum is ____ matter and contains ___
White
Myelinated axons
Folds in the cerebrum (raised part) are called
Gyri
The grooves in the cerebrum separating the gyri are called
Sulci (shallow)
Fissures (deeper)
What are the lobes the cerebrum is divided in to? (5)
Frontal
Occipital
Temporal
Parietal
Ventral cerebrum