Nervous System 1 Flashcards

1
Q

One of the two major control systems of the body mediating systemic homeostatic processesmuscle contractionintegration of blood oxygen, carbon dioxide, and pH levels via respiratory activityregulation of volumes and pressures in the circulation via cardiovascular and urinary functiondigestive system motility and secretion

A

Nervous System

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2
Q

______ system is a quick fix to homeostatic disturbance

A

Nervous system

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3
Q

____ system is slower long term maintenance

A

Endocrine system

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4
Q

What are the functional units of the nervous system?

A

Neurons

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5
Q

What are the support cells of neurons?

A

Neuroglia

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6
Q

Nervous system uses a combo of ____ and _____ to communicate info around body

A

chemical and electrical signals

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7
Q

_____ are stimulated by environmental changes or the activities of other cells

A

Dendrites

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8
Q

____ contains the nucleus and mitochondria, and other organelles and inclusions

A

Cell body

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9
Q

____ conducts nerve impulse toward synaptic terminals

A

Axon

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10
Q

_____ are clusters of ribosomes in cell body

A

Nissl Bodies

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11
Q

______ affect another neuron or effector organ

A

Synaptic terminals

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12
Q

_____ are clusters of myelin

A

Internodes

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13
Q

____ are formed by neuroglial cells

A

Internodes

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14
Q

____ form myelin for axons in CNS

A

Oligodendrocytes

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15
Q

____ form myelin for axons in PNS

A

Schwann cells

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16
Q

Internodes separated by small segments of axon not covered in myelin called ______Function: Speed up the rate of nerve impulse conduction (Saltatory conduction)

A

Nodes of Ranvier

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17
Q

(pseudounipolar neurons, bipolar)Afferent division of PNSCarry sensory information from reflex receptor to CNSDendrites/Cell body in PNSAxons typically myelinated and extend into CNS

A

Sensory Neurons

18
Q

(Multipolar neurons)Efferent division of PNSCarry motor commands from CNS to EFFECTORSDendrites/Cell body in CNSAxons typically myelinated, extend into PNS and synapse with effectors

A

Motor Neurons

19
Q

(Multipolar, Anaxonic)Found only in the CNSCarry information from one neuron to anotherIntegration

A

Interneurons

20
Q

Always the same (depolarization followed by repolarization) with no change in strength or size as they travel along the membrane–All-or-none –Triggered at Axon Hillock when Threshold Potential reached (Vm at which AP triggered; typically around -50mV))–Always propagates along cell membrane of axon from axon hillock toward axon terminals –Relatively fast changes in Vm

A

Action potential

21
Q

(Vm at which AP triggered; typically around -50mV))

A

Threshold Potential

22
Q

–Small changes in membrane potential of variable strength/amplitude –Only travel a short distance along membrane and lose strength as they travel–Often last longer than APs; Ex. IPSP and EPSP

A

Graded Potentials (GP):

23
Q

(depolarizations); moves Vm towards threshold potential; increases likelihood of AP

A

EPSPs. Excitatory postsynaptic potentials

24
Q

(hyperpolarizations); moves Vm away from threshold; decreases likelihood of AP

A

IPSPs. Inhibitory postsynaptic potentials

25
Q

Closed at resting Vm, quickly opens at threshold depolarization (Na+)

A

Voltage-gated Na channel Activation gate

26
Q

Open at resting Vm, slowly closes at threshold depolarization (Na+)

A

Voltage-gated Na channel Inactivation gate

27
Q

Single voltage gate begins to open at threshold, but is slow–delayed by the same time as the VG Na+ channel’s inactivation gate.

A

Voltage-gated K+ channel

28
Q

Voltage-gated Na channel opens at _____

A

threshold membrane potential

29
Q

Voltage-gated K channel opens at ______

A

peak of AP

30
Q

During this time it is impossible for the cell to fire another action potential. Due to all-or-none activation & the voltage-gated Na+channels’ closed inactivation gates; can’t fire another AP during this point

A

Absolute Refractory Period

31
Q

During this time a larger-than-normal EPSP can elicit an action potential. Due to: Some Na+ channels resetting to resting state After hyperpolarization; can fire another AP; resets Na channels

A

Relative Refractory Period

32
Q

______ increases membrane excitability; ;depolarizes membrane potential moving closer to threshold

A

Hyperkalemia 3.5

33
Q

_____ reduces membrane excitability; depolarizes membrane and cause inactivation of VG Na channels

A

Hyperkalemia >6Mm

34
Q

_____ reduces membrane excitability; hyperpolarizes membrane further from threshold

A

Hypokalemia

35
Q

____ binds to external surfaces of Na+ channel setting their excitable state

A

Calcium

36
Q

Relating to Ca, ____ reduces membrane excitability

A

Hypercalcemia

37
Q

Relating to Ca, ____ increases membrane excitability

A

Hypocalcemia

38
Q

____ functions as an insulator on an axon; speeds up conduction velocity of AP; conserves axon energy; helps produce saltatory conduction

A

Myelin

39
Q

What are the 2 factors that determine speed of an AP?

A

Axon diameter and myelin

40
Q

____ is an autoimmune demyelination disease of the CNS

A

Guillain-Barre Syndrome

41
Q

____ is an autoimmune demyelination disease of the PNS

A

Multiple Sclerosis