Nervous System 1 Flashcards
How many nerve pairs in PNS
43
12 pairs of cranial nerves (bypass spinal cord)
31 pairs of spinal nerves
Two subdivisions of the nervous system
CNS (brain and spinal cord)
Peripheral NS (PNS) - nerves leading to and from CNS
3 functions of NS
Sensory
Integrative
Responsive
Sensory
Detection of internal/external changes
Integrative
To decide on a course of action
Responsive
Motor neurons –> adjustments
Plastic
Changeable/mold-able
-the brain is plastic
What controls entire body?
nervous (fast) and endocrine systems (hormones- more slowly)
3 properties of nerve cells
Excitability, conductivity, and secretion of neurotransmitters and other chemical messengers
How and how fast does the nervous system transmit messages?
Using both electrical impulses and neurotransmitters at great speed (1-10 msec.)
Go/stop very quickly
Are NS effects local? When does the response stop?
It’s effects are relatively local and the response stops when the stimulus ceases
In the NS, what does prolonged stimulation result in?
Adaptation
How does the endocrine system send messages?
Send chemical messages (hormones) into the bloodstream that are generally much slower to act
Diff between where NS messages go and endocrine messages go
NS- effects are relatively local
Endocrine- send chemical messages (hormones) into bloodstream
What can responses in endocrine system be?
Systemic (affects entire body)- are slow to adapt and last long after the stimulation ceases
Exception to endocrine responded being systemic- slow to adapt and last long after stim ceases
Adrenaline (epinephrine)
Neuroglia
Cell of nervous system that’s NOT neurons
Helper cells of nervous tissue; bind neurons together and provide a supportive framework among other functions.
How many neuroglia are there compared to neurons and what do they NOT do?
They outnumber neurons 50 to 1
They do NOT conduct an impulse
6 types of neuroglia
Schwann cells (PNS), satellite cells (PNS), oligodendrocytes (CNS), astrocytes (CNS), ependymal cells (CNS), and Microglia (CNS).
Schwann cells
(Neuroglia in PNS)
Form neurilemma (membrane) around all cells they cover and often a myelin sheath around neuron fibers they cover in successive wrappings. Necessary for the regeneration of cut neurons.
Myelin sheath
Not every nerve has this; light in color fat
Cover neurons so impulse can move very fast
How do schwann cells make myelin
Make concentric circles around nerve
Gaps of Schwann cells are called ..
Nodes of ranvier
Covered sections of schwann cells are called…
Internodes
Satellite cells in PNS
Little is known of their function
Saltatory conduction
Electrical impulse on myelinated cell
Where on a neuron does myelin cover
Axon NEVER dendrites
Both neurilemma and myelin around one axon
What do you need to repair nerves
Need schwann cells
Oligodendrocytes
(Neuroglia- CNS)
Name=a few branches
Form myelin sheaths in CNS and wrap several cells
**Saltatory conduction is possible here also
Can one oligodendrocyte myelinate many axons?
YES
Astrocytes
(Neuroglia- CNS)
- Abundant, star-shaped cells in CNS
- In contact with endothelial cells (doesn’t conduct electrical impulse)
- produce some factors that encourage some stem cells to become transformed into neurons; under specific lab conditions, some stem cells can be coaxed into becoming astrocytes
What USED to be the believed function of astrocytes
We’re believed to be a major component of the blood brain barrier.
What is the blood brain barrier now recognized for
It’s recognized to be more attributable to tight junctions and the basal lamina of the endothelium in the brain
Ventricles
Spaces in the brain (4) lines with epithelium inside; there are ependymal cells that make cerebral spinal fluid
Ependymal cells
(CNS- nueroglia)
Helper cells- Produce and circulate cerebral spinal fluid (CSF); lines cavities in brain and spinal cord; MAY BE CILIATED
Microglia
(Neuroglia-CNS)
Helper cells- Small mobile macrophages develop from monocytes (wbc) and wander freely through CNS
get rid of waste
Soma/perikaryon
Control center of neuron (cell body) contains the nucleus and nucleolus, Nissl bodies (rough ER), supportive neurofibrils, and pigment (lipofuscin or “aging bodies”)
Nissl bodies (rough ER)
Contain ribosomes that make protein- makes something
Lipofuscin
“Aging bodies”
In soma of neuron; a harmless by-product of lysosomal breakdown (so by this we can tell how old a neuron is)
How can we tell how old a neuron is
By looking at the soma where there is lipofuscin (aging bodies)
What do mature neurons lack?
Centrioles and do not undergo mitosis past adolescence (neurons generally don’t divide)
Major cytoplasmic inclusions
(Not membrane bound)
Glycogen granules
Lipid droplets
Melanin (pigment)
Lipofuscin
Dendrites
Cellular extensions from the cell body that have receptors for neurotransmitters and recover signals from other neurons
Axon hillock
Gives rise to axon; axons vary greatly in length and end in a synaptic end bulb through which neurotransmitters are passed to the next neuron
Large neural fibers
In neuron, conduct impulses more rapidly than small ones
Myelinated fibers
Whitish color, FASTER than those that are non-myelinated bc ability to do Saltatory conduction
Collateral
Even if neuron is cut, it can use “side roads” to get where it needs to go.
can axons split?
Yes
Bipolar neuron
Neurons with one axon and one dendrite
Unipolar
(Ganglia outside CNS)
Neurons with one extension from the soma, branches shortly thereafter: peripheral process and central process.