Nerve, Muscle Flashcards

1
Q

Fibroblasts

A

secretes proteins of structural connective tissue

Collagen, reticulin, elastin

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2
Q

Collagen

A

triple-stranded, insoluble, fibrous. Highly cross-linked, high tensile strength—most abundant in mammals

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3
Q

Chondrocyte

A

secretes cartilage

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4
Q

osteoblast

A

secrete collagen (1/3) of bone mass

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5
Q

mast cells

A

found in respiratory and GI tract, •Release histamines that respond to allergic reaction, infection, injury
•Increase blood flow to affected area

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6
Q

Calcium channels

A

As action potential reaches bouton, triggers opening
• Causes synaptic vesicles to fuse with presynaptic membrane and release NT into cleft
• Ca pumped out of cytosol and back into ECF

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7
Q

Acetylcholinisterase

A

binds to surface of postsynaptic membrane and hydrolyzes acetylcholine to acetate and choline, which are recycled into presynaptic and used to make more

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8
Q

Z-line (sarcomere)

A

boundary of each contractile unit

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9
Q

Actin

A

thin contractile protein
• In I-bands, between the myosin A-bands
• Composed of G actin, roughly spherical in shape
• Two rows of G actin monomers form helix

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10
Q

I-band

A

contains actin, between myosin A-bands

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11
Q

A-band

A

contains myosin

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12
Q

Myosin

A

Thick contractile protein
• A-band region
• H zone is the part between actin filaments
• Arranged towards center of sarcomere, give dark bands on muscle tissue
• Myosin heads concentrated on terminal regions
• ATP bound to myosin heads reduces its affinity to bind to actin

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13
Q

H-zone

A

space between actin filaments

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14
Q

Tropomyosin

A

runs the length of grooves in actin, covers up binding sites and prevents head groups of myosin from attaching

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15
Q

Troponin

A

•When Ca is bound, shifts position to expose myosin head binding sites, works with tropomyosin

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16
Q

Parasympathetic nerve fibers leave from the:

A

sacral poprtion of spinal cord and from the midbrain (mesencephalon) and from medulla rhombencephalon)

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17
Q

Parasympathetic pre/postganglionic nerve length, NT

A

pre: long, post: short. Both release ACh (cholinergic)

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18
Q

Most prominent parasympathetic nerve

A

Vagus. Innervates heart, lungs, stomach, liver, small and large intestine, kidneys, etc

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19
Q

Sympathetic nerve fibers branch from:

A

thoracic and lumbar

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20
Q

Sympathetic pre/postganglionic nerve length, NTs

A

pre: short, ACh (cholinergic) post: long, norepinephrine (adrenergic) .

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21
Q

Pacinian corpuscle

A

unmyelinated nerve ending encapsulated in layers of connective tissue
• Afferent nerve that leaves is myelinated
• Amplitude of action potentials never increases, only frequency

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22
Q

Astrocyte

A

Nourish neurons and form the BBB, which controls the transmission of solutes from bloodstream into nervous tissue

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23
Q

Ependymal cells

A

line ventricles of brain and produce cerebrospinal fluid, which physically supports the brain and serves as a shock absorber

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24
Q

Microglia

A

Phagocytic cells that ingest and break down waste products and pathogens in CNS

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25
Na+/K+ ATPase
pumps three sodium ions out of the cell for every two potassium in
26
Excitatory signals cause
Depolarization
27
Inhibitory signals cause
Hyperpolarization
28
Electrochemical gradient
Sodium flows into the nueron and continues depolarizing it
29
Refractory period
When axon is hyperpolarized
30
Absolute refractory period
Cell is unable to fire another action potential
31
Relative refractory period
Requires a larger stimulus to fire an action potential
32
Reuptake channels
Absorb NTs back into the presynaptic cell
33
White/ grey matter in spinal cord and brain
Brain: white matter is deeper | Spinal cord: grey matter is deeper
34
White matter
Myelinated axons
35
Grey matter
Unmyelinated cell bodies and dendrites
36
Reflex arcs
Use ability of interneurons in the spinal cord to relay info to the source of stimuli while simultaneously routing it to the brain
37
Monosynaptic reflex arc
sensory (afferent, presynaptic) neuron fires directly onto the motor (efferent, postsynaptic) neuron
38
Polysynaptic reflex arc
Sensory neuron may fire onto a motor neuron as well as interneurons that fire onto other motor neurons
39
How many types of info can nerves carry
more than one
40
How many types of info can tracts carry
only one
41
Where to sensory neurons go
Afferent, enter spinal cord on dorsal side
42
In which neural structure are ribosomes primarily located?
Soma
43
Accidentally clip a root ganglion during spinal surgery, what is a likely consequence?
Loss of sensation at that level
44
Bundle of axons in CNS is called a
Tract, cell bodies are grouped into nuclei
45
Bundles of neurons in PNS
Nerves. Sensory, motor, or mixed | Cell bodies cluster into ganglia
46
Dorsal root ganglia
Where are cell bodies of sensory neurons found
47
Motor neurons exit the spinal cord (ventrally/dorsally)
Ventrally
48
Binding of GABA to postsynaptic receptor most likely results in:
Hyperpolarization and generation of IPSP
49
Pathway of pain in right hand from brain back to hand
Efferent nerve tract and ventral horn via somatic nervous system
50
Tonic receptors
Respond continuously for entire duration of stimulus (nociceptors)
51
Phasic receptors
Respond quickly to stimulus but stop soon after (Thermoreceptors)
52
phi phenomenon
apparent motion caused by rapid succession of stationary stimuli (flipbooks)
53
Where are sympathetic preganglion nerve bodies?
Thoracic and lumbar spinal cord. Also called "thoraco-lumbar system"
54
Where are parasympathetic preganglionic neuron cell bodies?
Brainstem or sacral portion of spinal cord. "craniosacral system"
55
Which of the pre/post ganglionic neurons uses Norepi?
Sympathetic postganglionic neuron
56
Adrenal medulla is derived from what tissue?
Sympathetic postganglionic neurons.
57
Pacinian corpuscules
Mechanoreceptors deep in the skin. Shaped like an onion , concentric layers of membranes that depolarize with pressure (graded not action potentials)
58
Electromagnetic receptors
Rods and cone cells in retina (photoreceptors) | In other animals, there are also magnetoreceptors
59
Golgi tendon organs
Monitor tension in the tendons
60
Joint capsule receptors
Detect pressure, tension, movement in the joints