Nerve, Muscle Flashcards
Fibroblasts
secretes proteins of structural connective tissue
Collagen, reticulin, elastin
Collagen
triple-stranded, insoluble, fibrous. Highly cross-linked, high tensile strength—most abundant in mammals
Chondrocyte
secretes cartilage
osteoblast
secrete collagen (1/3) of bone mass
mast cells
found in respiratory and GI tract, •Release histamines that respond to allergic reaction, infection, injury
•Increase blood flow to affected area
Calcium channels
As action potential reaches bouton, triggers opening
• Causes synaptic vesicles to fuse with presynaptic membrane and release NT into cleft
• Ca pumped out of cytosol and back into ECF
Acetylcholinisterase
binds to surface of postsynaptic membrane and hydrolyzes acetylcholine to acetate and choline, which are recycled into presynaptic and used to make more
Z-line (sarcomere)
boundary of each contractile unit
Actin
thin contractile protein
• In I-bands, between the myosin A-bands
• Composed of G actin, roughly spherical in shape
• Two rows of G actin monomers form helix
I-band
contains actin, between myosin A-bands
A-band
contains myosin
Myosin
Thick contractile protein
• A-band region
• H zone is the part between actin filaments
• Arranged towards center of sarcomere, give dark bands on muscle tissue
• Myosin heads concentrated on terminal regions
• ATP bound to myosin heads reduces its affinity to bind to actin
H-zone
space between actin filaments
Tropomyosin
runs the length of grooves in actin, covers up binding sites and prevents head groups of myosin from attaching
Troponin
•When Ca is bound, shifts position to expose myosin head binding sites, works with tropomyosin
Parasympathetic nerve fibers leave from the:
sacral poprtion of spinal cord and from the midbrain (mesencephalon) and from medulla rhombencephalon)
Parasympathetic pre/postganglionic nerve length, NT
pre: long, post: short. Both release ACh (cholinergic)
Most prominent parasympathetic nerve
Vagus. Innervates heart, lungs, stomach, liver, small and large intestine, kidneys, etc
Sympathetic nerve fibers branch from:
thoracic and lumbar
Sympathetic pre/postganglionic nerve length, NTs
pre: short, ACh (cholinergic) post: long, norepinephrine (adrenergic) .
Pacinian corpuscle
unmyelinated nerve ending encapsulated in layers of connective tissue
• Afferent nerve that leaves is myelinated
• Amplitude of action potentials never increases, only frequency
Astrocyte
Nourish neurons and form the BBB, which controls the transmission of solutes from bloodstream into nervous tissue
Ependymal cells
line ventricles of brain and produce cerebrospinal fluid, which physically supports the brain and serves as a shock absorber
Microglia
Phagocytic cells that ingest and break down waste products and pathogens in CNS