Amino Acids Flashcards
1
Q
AA with side chain pKa close to phys pH:
H, E, R, D
A
H
2
Q
Which contains selenol group?
A
U, selenocysteine
3
Q
Primary excitatory NT in the brain is
A
E, glutamate
4
Q
Within pH 0-14, all have dissociable proton on side chain EXCEPT
T, O, Y, S
A
O, pyrolysine
5
Q
Most basic side chain?
N, E, R, D
A
R, Arginine
6
Q
Essential AAs
A
WTF MLK HIV
7
Q
Indole derivative, serotonin precursor
A
W, tryptophan
8
Q
Which AA substitution leads to sickle-cell disease
A
E –> V, Glutamate –> Valine
9
Q
Most likely to disrupt alpha helix,
P, I, C, K
A
Proline
10
Q
Elution order for column buffered at pH=6
LERH (fix it)
A
RHLE
11
Q
Hydrophobic amino acids share what properties/ what are they
A
Valine, leucine, isolucine, etc.
Nonpolar, uncharged R groups
