Nephrology Flashcards
Goodpasture’s syndrome Fx
pulmonary haemorrhage (haemoptysis)
glomerulonephritis (haematuria)
anti-glomerular basement membrane (anti-GBM) antibodies
Increased Specific gravity on urine dip (concentrated urine)
dehydration
glycosuria
proteinuria
renal artery stenosis
SIADH
CCF (reduced blood flow to kidneys)
Decreased specific gravity on urine dip (dilute urine)
excessive fluid intake
renal failure
pyelonephritis
diabetes insipidus
Interstitial cystitis (bladder pain syndrome)
diagnosis of exclusion
prolonged duration
pelvic pain
urinary symptoms
MX UTI in women (uncomplicated)
1st - Nitrofurantoin/ Trimethoprim
2nd - Nitrofurantoin/ Pivmecillanem/ Fosfomycin
Mx UTI in pregnancy
1st - Nitrofurantoin (avoid at term due to risk of neonatal haemolysis)
2nd - Amoxicillin/ Cefalexin
avoid trimethorpim
Mx UTI male
Nitrofurantoin/ Trimethoprim
UTI Abx duration
3 day
5-10 day
7 day
3 day - uncomplicated UTI, haematuria, recurrent UTI
5-10 - abnormal urinary tract, immunosuppression, impaired renal function
7d - pregnant, catheterised, male
Renal cell carcinoma Fx
haematuria (often painless)
flank/ loin pain
loin mass
(varicocele)
Male urethral injury (fracture) Ix
clinical diagnosis most of the time
retrograde urethrography or MRI
IgA nephropathy Fx
visible haematuria 24-48 hrs post URTI
Post streptococcus glomerulonephritis Fx
visible haematuria 1-3 weeks post UTRI
BPH Mx
1st - Tamsulosin (a1 adrenergic receptor inhibitor) - reduce smoother muscle of prostate
2nd - Finasteride (5a reductase inhibitor) - reduce dihydrotestosterone
3rd (minimally invasive) - TUMT (microwave)/ TUNA (needle)
4th (surgical) - TURP
BPH Mx
1st - Tamsulosin (a1 adrenergic receptor inhibitor) - reduce smoother muscle of prostate
2nd - Finasteride (5a reductase inhibitor) - reduce dihydrotestosterone
3rd (minimally invasive) - TUMT (microwave)/ TUNA (needle)
4th (surgical) - TURP
Autosomal dominant polycystic kidney disease associations
hepatic cysts (most common)
mitral valve prolapse
intracranial berry aneurysm
colonic diverticula
renal cell ca