Nephritis

Question 1

What is nephritis? Results from what?

Answer 1

Inflammation of glomerulus.-Immunological abnormalities most common.-Vascular disorder-System disease-Viral Causes

Question 2

What are the characteristics of nehpritis?

Answer 2

Less than 3.5 g of protein loss per day.-Hematuria (RBC Casts).-Azotemia-Hypertension

Question 3

What is acute postinfectious glomerulonephritis? Characteristics?

Answer 3

Following strep infection/Antigen-antibody complexes precipitate on glomerular membrane. -Capillary endo cell proliferation.

Question 4

What is IgA (bergers disease)? Characteristics?

Answer 4

Acute glomerulonephritis.-After 2-3 days after URT or GI viral infection.-IgA binds to mesangial cells inducing proliferation.

Question 5

What is Rapidly progressive glomerulonephritis (RPGN)? Characteristics?Also called?

Answer 5

Antiglomerular basement membrane disease. AKA Goodpasture syndrome.-Get cresent from fibrin cells.

Question 6

What is Chronic Glomerulonephritis? Examples? Charcteristics?

Answer 6

Varius disease cause slow progressive loss of renal function. -Diabetes mellitus (Glucose damages endo cells)-Hypertension (pressure damages glomerulus)-Autoimmunity.Get tubular atrophy, Slight proteinuriaWaxy and RBC casts in urine.

Question 7

What is pyelonephritis? Complicated vs uncomplicated.

Answer 7

Invasive kidney infection from UTI (E coli, Proteus). E coli mostly causes uncomplicated version.

Question 8

What is drug-induced interstitial nephritis?

Answer 8

Antibiotics, NSAIDS.IgE and T cell responseEosinophilia, hematuria.Analgesic nephritis is worse.