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Internal Medicine > Neoplasia > Flashcards

Neoplasia Flashcards

1
Q

What makes lymphoma different from leukemias?

A

Lymphoma originates from solid organs while leukemia orginates from bone marrow.

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2
Q

How many times more likely is a cat to get lymphoma that has FIV? FeLV and FIV?

A

FIV only = 6x

FIV and FeLV = 75x

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3
Q

What dog breeds commonly get B-Cell lymphoma?

A

Cockers and bassets

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4
Q

What dog breeds commonly get T-Cell lymphoma?

A

Boxers, Siberian huskies and shih tzus

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5
Q

Lymphoma has a what type of age distribution? Why ini cats is this thought to be?

A

Bimodal

Young cat = FeLV

Old cat = just normal Lymphoma

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6
Q

What are the four anatomic forms of lymphoma?

A

Multicentric - lymph nodes +/- spleen, liver, bone marrow

Mediastinal - Mediastinal lymph nodes +/- bone marrow

Alimentary - GI +/- intraabdominal lymphadenopathy

Extranodal - Renal, ocular, cutaneous

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7
Q

What anatomic form is most common in a dog? Cat?

A

Dog - Multicentric - 80% of cases

Cat - Alimentary - 70% of cases

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8
Q

Common first sign of lymphoma in dogs?

A

PU/PD - hypercalcemia. This is rare in cats

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9
Q

Most common extranodal lymphomas in dogs? Cats?

A

Dogs - cutaneous and ocular

Cats - nasopharyngeal, ocular, renal, neural

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10
Q

Donut shaped skin lesion consistent with?

A

Cutaneous lymphoma.

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11
Q

Most cats with cutaneous lymphoma do NOT have this?

A

FeLV …weird.

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12
Q

There is some reports of an association between what extranodal types of lymphoma in cats?

A

Neural and renal.

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13
Q

What are the three forms of CNS lymphoma?

A

Solitary epidural lymphoma

Neuropil (intracranial or intraspinal) lymphoma— Called TRUE CNS lymphoma

Peripheral nerve lymphoma.

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14
Q

Dogs with multicentric lymphoma commonly relapse into what?

A

CNS lymphoma.

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15
Q

What is the only clinically relevant paraneoplastic syndrom with lymphoma?

A

Hypercalcemia in dogs.

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16
Q

What paraneoplastic disease in dogs with lymphoma is rare in cats?

A

Hypercalcemia.

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17
Q

What does TNM mean?

A

Tumor, node, metastasis.. staging system

18
Q

What are the stages of lymphoma (5)?

A
  1. Solitary lymph node involvement
  2. More than one lymph node on one side of the diaphragm
  3. Generalized lymph node involvement
  4. Stage 3 plus hepatomegaly or splenomegaly
  5. Bone marrow or extranodal involvement
    1. A = Asymptomatic
    2. B = Sick
19
Q

What is the only prognostic indicator in the lymphoma staging scale in dogs?

A

Sick or not sick

20
Q

What breed of dog commonly has T-Cell lymphoma?

A

Boxers

21
Q

Hemangiosarcomas in dogs have a predilection for older dogs of what sex and breed (2)?

A

Males

German Shepherd

Goldens

22
Q

Greyhounds commonly get HSA where?

A

Hind leg musle

23
Q

What types of HSA are not aggressive?

A

Dermal and conjunctival.

24
Q

Spindle cells are a sign of what type of neoplasia?

A

Sarcoma.

25
Q

What is the probability of diagnosing HSA on cytology from effusion?

A

<25%

26
Q

What is the big difference between cats and dogs with primary bone tumors?

A

Cats can be cured with wide surgical excision.

27
Q

Canine OSA causes what in racing greyhounds vs show greyhounds?

A

Racing greyhounds: 25% of death

Show greyhounds: OSA is extremely rare.

28
Q

Unique places for osteosarcoma in Great danes, Rotties and Greyhounds?

A

Great danes - distal radius

Rotties and Grey hounds - proximal femur

29
Q

What is a negative prognostic indicator with OSA?

A

Lung mets

30
Q

What breed is at high risk for MCT?

A

Brachiocephalic

Goldens

31
Q

10-15% of MCT are indistinguishable from?

A

lipomas

32
Q

What are the three categories of MCT?

A

Well differentiated - 1

Moderately differentiated - 2

Differentiated - 3

33
Q

What type of metastasis is common with MCT?

A

Skip metastasis - every lymph node in the region should be aspirated.

34
Q

What percentage of dogs with advanced MCT have gastroduodenal ulceration?

A

80%

35
Q

What type of MCTs are seen in cats?

A

Visceral and cutaneous.

36
Q

Multiple intestinal masses in cats are most commonly associated with?

A

Lymphoma and MCT (can coexist)

37
Q

What is the biologic behavior of cutaneous mast cell in cats?

A

Benign

38
Q

What type of tumor is injection site sarcomas normally?

A

Fibrosarcoma

39
Q

What is the 3,2,1 rule for injection site tumor in cats?

A
  1. mass persists for more than 3 months
  2. mass is larger than 2cm
  3. mass grows 1 month after injection
40
Q

How do injection site sarcomas (FSA) differ from regular FSA?

A

Injection site sarcomas (FSA) are much more aggressive.

Internal Medicine (12 decks)

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