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Vet Path. > Neoplasia > Flashcards

Neoplasia Flashcards

1
Q

Young K9s more likely to have what kind of tumors

A

Hematopoietic, skin, brain tumors

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2
Q

Mast cell tumors common in

A

Young K9, especially boxers

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3
Q

Most frequent neoplasia in cats and cattle

A

Lymphoid neoplasia

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4
Q

Neonatal claves get

A

Mesotheliomas

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5
Q

Young horses get

A

Cutaneous neoplasms

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6
Q

Boxers

A

High neoplasia

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7
Q

GSD get

A

Hemangiosarcomas

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8
Q

Lg breed dogs get

A

Osteosarcomas

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9
Q

Brachycephalics get

A

CNS and aortic body tumors

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10
Q

Sinclair and hormel mini pigs & duroc-jersey swine get

A

Melanomas

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11
Q

Bernese mountain dogs get

A

Malignant histiocytosis

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12
Q

Cows & horses predisposed to

A

Granulosa thecal cell tumors

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13
Q

Cats & cattle predisp. To

A

Lymphosarcoma (FeLV & BLV)

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14
Q

Cats susc. To

A

Vx site sarcomas

(Don’t inject between scapula)

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15
Q

Horses predisp. To

A

Sarcoid; pedunculated lipoma

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16
Q

K9 predisp. To

A

Mammary gland neoplasia

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17
Q

Chickens predisposed to

A

Marek’s disease

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18
Q

White coated animals predisp. To

A

Squamous cell carcinomas

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19
Q

Grey horses get

A

Melanomas

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20
Q

Spirocepta lupi causes sarcomas in what animal?

A

K9

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21
Q

Factors that predispose animals to neopplasia

A

Heredity, age, gender, pigment, hormones, chronic irritation, parasited

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22
Q

Excessive hormone stimulation usually causes

A

Tumor development

23
Q

Mammary tumors and perianal gland tumors assc. w/

A

Genetic predisp.

24
Q

T or F: spaying K9 before 1st estrus creates 1% risk of mammary neoplasia

A

True

25
Q

Clinical features

A
  • abnormalities assc. w/ affected organs
  • cancer cachexia
  • outward lesions
  • paraneoplastic syndromes
26
Q

Paraneoplastic syndromes

A
  • systemic complications/illnesses of neoplasia remote from primary tumor
  • can be early sign of occult neoplasm
  • can confound treatment
  • can cause severe illness/patient death
27
Q

Product concentration in paraneoplastic syndromes

A
  • maintained after removal of normal control gland
  • decreases after removal or tx of neoplasm
28
Q

Types of paraneoplastic syndromes

A
  • endocrinopathies
  • neuromuscular disorders
  • dermatologic disorders
  • osseous, articular, soft tissue changes
  • hematologic and vascular changes
29
Q

Endocrinopathy types

A
  • hypercalcemia of malignancy
  • cushing’s
30
Q

Osseous, articular, soft tissue change neoplasm types

A

Hypertrophic osteoarthropathy

31
Q

Underlying cancer of cushing’s

A
  • small cell cancer of the lung
  • pancreatic carcinoma
  • neural tumors
32
Q

Underlying cancer of hypercalcemia

A
  • squamous cell carcinoma of lung
  • renal carcinoma
  • breast carcinoma
  • adult lymphoma/leukemia
33
Q

Underlying cancer of polycythemia

A
  • renal carcinoma
  • hepatocellular carcinoma
34
Q

Underlying cancer of myasthenia gravis

A

Thymoma

35
Q

Underlying cancer of hypertrophic osteoarthropathy

A

Lung adenocarcinoma

36
Q

Underlying cancer of non-bacterial thrombotic endocarditis

A

Advance cancers

37
Q

Hypertrophic osteoarthropathy

A
  • assc w/ pulmonary tumors
  • not a neoplasm
  • proliferation of osseous tissue in distal limbs
38
Q

Myasthenia gravis

A
  • thymoma paraneoplastic syndrome
  • thymic neoplastic cells that produce anti-ACh receptor antibodies
39
Q

Pathologic neoplasm dx

A
  • biopsy
  • cytology
  • flow cytometry
  • necropsy
40
Q

Gold standard for neoplasm dx

A

H&E

41
Q

GRADING OF CANCER IS

A

HISTOLOGIC

42
Q

STAGING OF CANCER IS

A

CLINICAL

43
Q

Staging or grading is more valuable in the clinics

A

Staging

44
Q

Grading

A
  • estimates aggressiveness or malignancy lvl based on cytologic diff. Of tumor cells & mitosis #s
  • grades 1-4
45
Q

Staging

A
  • describes size of tumor & extent of spread/presence of metastasis
  • TNM system used
46
Q

TNM System

A
  • T= primary tumor size ( small is 1 and largest is 4)
  • N= node involvement
  • M: absence or presence of distant metastases (m0 is no M1 is yes)
47
Q

Conventional cancer tx

A
  • sx
  • chemo
  • radium & other radioactive materials
  • immunotherapy
48
Q

Gold standard sx procedure for cancer tx

A
  • 3cm margins on all sides
  • ink sx margins and tag w/suture
49
Q

Chemotherapy protocol for K9 lymphoma

A

CHOP
- Cyclophosphamide

  • doxorubicin
  • oncovin
  • prednisone
50
Q

Radiation tx

A
  • beams (external)
  • radioisotopes (internal; I-131 for thyroid tumors)
  • can be used for palliative care
51
Q

1st usda approved K9 cancer vx for melanoma

A

Oncept

52
Q

Monoclonal abs for b lymphocytes

A

Blontress

53
Q

Monoclona abs for t lymphocytes

A

Tactress

54
Q

Unconventional tx for cancer

A
  • holistic tx
  • special diets
  • acupuncture

Vet Path. (10 decks)

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