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Neoplasia Flashcards

1
Q

Young K9s more likely to have what kind of tumors

A

Hematopoietic, skin, brain tumors

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2
Q

Mast cell tumors common in

A

Young K9, especially boxers

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3
Q

Most frequent neoplasia in cats and cattle

A

Lymphoid neoplasia

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4
Q

Neonatal claves get

A

Mesotheliomas

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5
Q

Young horses get

A

Cutaneous neoplasms

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6
Q

Boxers

A

High neoplasia

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7
Q

GSD get

A

Hemangiosarcomas

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8
Q

Lg breed dogs get

A

Osteosarcomas

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9
Q

Brachycephalics get

A

CNS and aortic body tumors

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10
Q

Sinclair and hormel mini pigs & duroc-jersey swine get

A

Melanomas

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11
Q

Bernese mountain dogs get

A

Malignant histiocytosis

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12
Q

Cows & horses predisposed to

A

Granulosa thecal cell tumors

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13
Q

Cats & cattle predisp. To

A

Lymphosarcoma (FeLV & BLV)

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14
Q

Cats susc. To

A

Vx site sarcomas

(Don’t inject between scapula)

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15
Q

Horses predisp. To

A

Sarcoid; pedunculated lipoma

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16
Q

K9 predisp. To

A

Mammary gland neoplasia

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17
Q

Chickens predisposed to

A

Marek’s disease

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18
Q

White coated animals predisp. To

A

Squamous cell carcinomas

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19
Q

Grey horses get

A

Melanomas

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20
Q

Spirocepta lupi causes sarcomas in what animal?

A

K9

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21
Q

Factors that predispose animals to neopplasia

A

Heredity, age, gender, pigment, hormones, chronic irritation, parasited

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22
Q

Excessive hormone stimulation usually causes

A

Tumor development

23
Q

Mammary tumors and perianal gland tumors assc. w/

A

Genetic predisp.

24
Q

T or F: spaying K9 before 1st estrus creates 1% risk of mammary neoplasia

25
Clinical features
- abnormalities assc. w/ affected organs - cancer cachexia - outward lesions - paraneoplastic syndromes
26
Paraneoplastic syndromes
- systemic complications/illnesses of neoplasia remote from primary tumor - can be early sign of occult neoplasm - can confound treatment - can cause severe illness/patient death
27
Product concentration in paraneoplastic syndromes
- maintained after removal of normal control gland - decreases after removal or tx of neoplasm
28
Types of paraneoplastic syndromes
- endocrinopathies - neuromuscular disorders - dermatologic disorders - osseous, articular, soft tissue changes - hematologic and vascular changes
29
Endocrinopathy types
- hypercalcemia of malignancy - cushing’s
30
Osseous, articular, soft tissue change neoplasm types
Hypertrophic osteoarthropathy
31
Underlying cancer of cushing’s
- small cell cancer of the lung - pancreatic carcinoma - neural tumors
32
Underlying cancer of hypercalcemia
- squamous cell carcinoma of lung - renal carcinoma - breast carcinoma - adult lymphoma/leukemia
33
Underlying cancer of polycythemia
- renal carcinoma - hepatocellular carcinoma
34
Underlying cancer of myasthenia gravis
Thymoma
35
Underlying cancer of hypertrophic osteoarthropathy
Lung adenocarcinoma
36
Underlying cancer of non-bacterial thrombotic endocarditis
Advance cancers
37
Hypertrophic osteoarthropathy
- assc w/ pulmonary tumors - not a neoplasm - proliferation of osseous tissue in distal limbs
38
Myasthenia gravis
- thymoma paraneoplastic syndrome - thymic neoplastic cells that produce anti-ACh receptor antibodies
39
Pathologic neoplasm dx
- biopsy - cytology - flow cytometry - necropsy
40
Gold standard for neoplasm dx
H&E
41
GRADING OF CANCER IS
HISTOLOGIC
42
STAGING OF CANCER IS
CLINICAL
43
Staging or grading is more valuable in the clinics
Staging
44
Grading
- estimates aggressiveness or malignancy lvl based on cytologic diff. Of tumor cells & mitosis #s - grades 1-4
45
Staging
- describes size of tumor & extent of spread/presence of metastasis - TNM system used
46
TNM System
- T= primary tumor size ( small is 1 and largest is 4) - N= node involvement - M: absence or presence of distant metastases (m0 is no M1 is yes)
47
Conventional cancer tx
- sx - chemo - radium & other radioactive materials - immunotherapy
48
Gold standard sx procedure for cancer tx
- 3cm margins on all sides - ink sx margins and tag w/suture
49
Chemotherapy protocol for K9 lymphoma
CHOP - Cyclophosphamide - doxorubicin - oncovin - prednisone
50
Radiation tx
- beams (external) - radioisotopes (internal; I-131 for thyroid tumors) - can be used for palliative care
51
1st usda approved K9 cancer vx for melanoma
Oncept
52
Monoclonal abs for b lymphocytes
Blontress
53
Monoclona abs for t lymphocytes
Tactress
54
Unconventional tx for cancer
- holistic tx - special diets - acupuncture

Vet Path. (10 decks)

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