Neisseria and Moraxella

Question 1

What are the Gram negative diplococci?

Answer 1

Neisseeria and Moraxella

Question 2

Neisseria is ______ shaped.

Answer 2

coffee bean-kidney

Question 3

What are the common features of neisseria and moraxella?

Answer 3

Catalase +
Oxidase +
Non motile
Humans are host

Question 4

Which biochemical test do we use the most for neisseria?

Answer 4

Carbohydrate utilization test

Question 5

What are the microscopic features of neisseria ?

Answer 5

Non hemolytic
Translucent
Well defined margin

Question 6

What are the species of Neisseria ?

Answer 6

N.sicca(glucose,maltose,sucrose+)
N.flavescens(none)
N.gonorrhea(only glucose)
N.meningitidis(glucose+maltose)

Question 7

Which of the 2 Neisseria species are pathogenic for humans?

Answer 7

N.gonorrhea

N.meningitis

Question 8

Which neisseria is fastidious?

Answer 8

N.gonorrhea

Question 9

What are the agars that we use for N.gonorrhea?

Answer 9

Blood
Chocolate
Thayer-Martin

Question 10

Which Neisseria is capnophilic?(%5-10 co2)

Answer 10

N.gonorrhea

Question 11

In which neisseria prostitudes are reservoir?

Answer 11

N.gonorrhea

Question 12

What are the outer membane proteins of gonorrhea?

Answer 12

Por
Opa
RMP

Question 13

Gonorrhea is an _____ disease

Answer 13

Sexually transmitted

Question 14

Gonorrhea is asymptomatic in %50 of ___ and causes acute urethritis in ___.

Answer 14

1-Female

2-Male

Question 15

N.gonorrhea causes _____ in neonates.

Answer 15

Opthalmia Neonatarum(Neonate Conjunctivitis)

Question 16

What do we use for prophylaxis of gonorrhea in neonates?

Answer 16

Silver nitrate

Question 17

What is the frequency of disseminated infections and which sex is the most susceptible for disseminated infections of gonorrhea?

Answer 17

%1-3

Female(bcs of menstruation)

Question 18

What are the sites of dissemination in gonorrhea?

Answer 18

JOİNTS
HEART
PHARYNX
MENİNGES

Question 19

What is the clinical presentation of acute urethritis?

Answer 19

MALE
Dysuria
Urethral discharge
Painful swollen testicles

Question 20

What is the microscopic appearance of N.gonorrhea and N.meningitidis?

Answer 20

Pink and paired

Question 21

What is the microscopic Ddx of N.meningitidis from N.gonorrhea?

Answer 21

ENCAPSULATED N.MENİNGİTİDİS

Question 22

What is the site of colonization for N.meningitidis?

Answer 22

Nasopharynx

Question 23

What are the virulence factors of N.gonorrhea?5 TANE

Answer 23

Pili
Outer membrane proteins(POR.OPA.RMP)
Lipooligosaccharide
IgA1 protease
Iron binding protein

Question 24

What are the virulence factors of N.meningitidis?5 TANE

Answer 24

Pili
Polysaccharide capsule
Lipooligosaccharide
IgA1 protease
Iron binging proteins

Question 25

Meningococcemia-Meningitis?

Answer 25

N.meningitidis can cause it | In meningococcemia is characterized by petechial skin lesions

Question 26

What is the main Ddx method of moraxella from neisseria?

Answer 26

Moraxella is asacchoralytic. Moraxella has SLİDİNG COLONİES. Moraxella has DNAase

Question 27

Moraxella features?

Answer 27

``` Capsulated Caphnophilic BETA lactamase+ we give penicllin+beta lactamase inhibitor Produce DNAase Non motile ```

Question 28

Most common moraxella specie?

Answer 28

M.catarrhalis--->Mostly in children | causes otitis media,conjunctivitis,bronchitis,pneumonia

Question 29

Stain smears are more ___ than endocervical smears for gonorrhea

Answer 29

SENSİTİVE

Question 30

GONORRHEA For STERİLE SİTE SPECİMEN we use _____ For NON STERİLE SİTE SPECİMEN we use _____

Answer 30

1-Blood/Chocolate agar | 2-Thayer martin agar

Question 31

Which epithelium does gonorrhea colonize at?

Answer 31

Transitional and columnar

Question 32

Gonorrhea is very susceptible to ____&______

Answer 32

Dryness&fatty acids

Question 33

Unlike streptococcal and pneumococcal carriers we should treat ____ CARRİERS with ANTİBİOTİC

Answer 33

Meningococcal

Question 34

Which groups are prone to decolorization and may seem false + under gram staining?

Answer 34

NEİSSERİA MORAXELLA ACİNOBACTER