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Infectious Disases Microbiology > Neisseria and Moraxella > Flashcards

Neisseria and Moraxella Flashcards

1
Q

What are the Gram negative diplococci?

A

Neisseeria and Moraxella

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2
Q

Neisseria is ______ shaped.

A

coffee bean-kidney

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3
Q

What are the common features of neisseria and moraxella?

A

Catalase +
Oxidase +
Non motile
Humans are host

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4
Q

Which biochemical test do we use the most for neisseria?

A

Carbohydrate utilization test

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5
Q

What are the microscopic features of neisseria ?

A

Non hemolytic
Translucent
Well defined margin

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6
Q

What are the species of Neisseria ?

A

N.sicca(glucose,maltose,sucrose+)
N.flavescens(none)
N.gonorrhea(only glucose)
N.meningitidis(glucose+maltose)

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7
Q

Which of the 2 Neisseria species are pathogenic for humans?

A

N.gonorrhea

N.meningitis

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8
Q

Which neisseria is fastidious?

A

N.gonorrhea

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9
Q

What are the agars that we use for N.gonorrhea?

A

Blood
Chocolate
Thayer-Martin

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10
Q

Which Neisseria is capnophilic?(%5-10 co2)

A

N.gonorrhea

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11
Q

In which neisseria prostitudes are reservoir?

A

N.gonorrhea

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12
Q

What are the outer membane proteins of gonorrhea?

A

Por
Opa
RMP

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13
Q

Gonorrhea is an _____ disease

A

Sexually transmitted

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14
Q

Gonorrhea is asymptomatic in %50 of ___ and causes acute urethritis in ___.

A

1-Female

2-Male

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15
Q

N.gonorrhea causes _____ in neonates.

A

Opthalmia Neonatarum(Neonate Conjunctivitis)

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16
Q

What do we use for prophylaxis of gonorrhea in neonates?

A

Silver nitrate

17
Q

What is the frequency of disseminated infections and which sex is the most susceptible for disseminated infections of gonorrhea?

A

%1-3

Female(bcs of menstruation)

18
Q

What are the sites of dissemination in gonorrhea?

A

JOİNTS
HEART
PHARYNX
MENİNGES

19
Q

What is the clinical presentation of acute urethritis?

A

MALE
Dysuria
Urethral discharge
Painful swollen testicles

20
Q

What is the microscopic appearance of N.gonorrhea and N.meningitidis?

A

Pink and paired

21
Q

What is the microscopic Ddx of N.meningitidis from N.gonorrhea?

A

ENCAPSULATED N.MENİNGİTİDİS

22
Q

What is the site of colonization for N.meningitidis?

A

Nasopharynx

23
Q

What are the virulence factors of N.gonorrhea?5 TANE

A 
Pili
Outer membrane proteins(POR.OPA.RMP)
Lipooligosaccharide
IgA1 protease
Iron binding protein
24
Q

What are the virulence factors of N.meningitidis?5 TANE

A 
Pili
Polysaccharide capsule
Lipooligosaccharide
IgA1 protease
Iron binging proteins
25
Q

Meningococcemia-Meningitis?

A

N.meningitidis can cause it

In meningococcemia is characterized by petechial skin lesions

26
Q

What is the main Ddx method of moraxella from neisseria?

A

Moraxella is asacchoralytic.
Moraxella has SLİDİNG COLONİES.
Moraxella has DNAase

27
Q

Moraxella features?

A 
Capsulated
Caphnophilic
BETA lactamase+ we give penicllin+beta lactamase inhibitor
Produce DNAase
Non motile
28
Q

Most common moraxella specie?

A

M.catarrhalis—>Mostly in children

causes otitis media,conjunctivitis,bronchitis,pneumonia

29
Q

Stain smears are more ___ than endocervical smears for gonorrhea

A

SENSİTİVE

30
Q

GONORRHEA
For STERİLE SİTE SPECİMEN we use _____
For NON STERİLE SİTE SPECİMEN we use _____

A

1-Blood/Chocolate agar

2-Thayer martin agar

31
Q

Which epithelium does gonorrhea colonize at?

A

Transitional and columnar

32
Q

Gonorrhea is very susceptible to ____&______

A

Dryness&fatty acids

33
Q

Unlike streptococcal and pneumococcal carriers we should treat ____ CARRİERS with ANTİBİOTİC

A

Meningococcal

34
Q

Which groups are prone to decolorization and may seem false + under gram staining?

A

NEİSSERİA
MORAXELLA
ACİNOBACTER

Infectious Disases Microbiology (12 decks)

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