Gram Negative Cocobacilli

Question 1

Gram negative coccobacilli’s?

Answer 1

Brucella
Francisella
Pasteurella

Question 2

What is Zoonoses?

Answer 2

Human diseases that are caused by animal reservoirs directly or via a vector indirectly

Question 3

Gram Negative Coccobacilli ____ EXOTOXİN,_____ ENDOTOXİN

Answer 3

-,+

Question 4

What are the common features of GNCB?

Answer 4

They stain fairly
Grow slowly
Have endotoxin but doesn't have exotoxin
Non motile
Oxidase +

Question 5

Which Gram negative coccobacilli are aeorobic?

Answer 5

Brucella&Francisella

Question 6

Which Gram negative coccobacilli are facultatively intracellular?

Answer 6

Brucella&Francisella

Question 7

Which Gram negative coccobacilli inhibit phagosome lysosome formation?

Answer 7

Brucella&Francisella

Question 8

Which Gram negative coccobacilli is facultative anaerobic?

Answer 8

Pasteurella

Question 9

Which Gram negative coccobacilli is catalase +?

Answer 9

Brucella

Question 10

____ loves organs rich in erythriols which are genital organs of animals.And that’s why causes ___ and ___ in animals

Answer 10

1) Brucella
2) Sterility
3) Abortion

Question 11

Erythriol is a ___ and is’___ found in humans

Answer 11

1) Carbohydrate

2) not

Question 12

Is there a vaccine for brucella?

Answer 12

Not for humans but there is for animals

Question 13

Is there a vaccine for francisella?

Answer 13

NO

Question 14

What is the most important transmission way of brucella?

Answer 14

İngestion of unpastorized dairy products

Question 15

What does Brucella cause?

Answer 15

Malta fever=Undulant fever=Mediterrinian remittent fever

Question 16

What are the reservoirs of B.melitensis?

Answer 16

goat,sheep,camel MOST COMMON AND VİRULENT

Question 17

What is the reservoir of B.abortus?

Answer 17

Cattle LEAST VİRULENT

Question 18

What are the effects of Brucella?

Answer 18

Hepatosplenomegaly,LAP,Meningitis
Brucellois,Encephalitis.Endocartidis,..
There are systemic effects also bcs via macrophage goes to RES organs and enters into bloodstream.

Question 19

Which Gram negative coccobacilli is enzonotic?

Answer 19

Francisella

Question 20

Which Gram negative coccobacilli is extremely infective and 10-50 mo is sufficient for infection?

Answer 20

Fransicella

Question 21

______ depends on route of infection for Fransicella

Answer 21

Infection dose

Question 22

You need 106-108 mo for ___ route,10-50 for ___&___ route of infection in francisella

Answer 22

1) GİS

2) skin&inhalation

Question 23

Fransicella biosafety level is ___.

Answer 23

3

Question 24

Fransicella can live in water,mud,dead animals for ___ months
Can live in dead frozen rabbit meat for ___ years.

Answer 24

1) 3-4

2) 3

Question 25

Francisella needs ___ containing substances,culture is rich in ___

Answer 25

1) Sulphur

2) Cysteine

Question 26

What are the Culture medias of Francisella?

Answer 26

Chocolate Agar
Thayer-Martin Agar
Buffered charcoal yeast extract agar

Question 27

What is Thayer-Martin Agar composed of?

Answer 27

It is Chocolate media+ ANTİBİOTİC

Question 28

What is the most commonly seen tularemia which is caused bcs F.tularensis?

Answer 28

Ulceroglandular tularemia

Question 29

Synonym of tularemia is______

Answer 29

Rabbit fever

Question 30

Which tularemia types have 30-60% mortality rate?

Answer 30

Typhoidal and Pneumonic

Question 31

What does typhoidal tularemia cause?

Answer 31

Typhoid fever

Question 32

THE MAJOR VİRULENCE FACTOR OF BRUCELLA İS _____ AND İT İS _____.

Answer 32

1) Lipopolysaccharide

2) Endotoxic

Question 33

In which gram negative coccobacilli PENİCİLLİN still WORKS?

Answer 33

Pasteurella

Question 34

What is the most pathogenic form of pasteurella?

Answer 34

P.multocida

Question 35

In which gram negative coccobacilli there is bipolar staining?

Answer 35

P.multocida

Question 36

In normal flora of;
%55 of dogs
%60-90 of cats
and some peoples nasopharynx?

Answer 36

Pasteurella

Question 37

Pasteurella causes ____& _____

Answer 37

LOCALİZED cellulitis&lymphadenitis

Question 38

When does pasteurella cause osteomyelitis?

Answer 38

When a cat bites you so sharply that toxin reaches to periosteum

Question 39

Pasteurella may cause systemic effects only in ____ patients.

Answer 39

İmmunosuppressed