Actinomycetes Flashcards

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1
Q

What are 2 main subclasses of actinomycetes?

A

Aerobic and Anaerobic

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2
Q

Anaerobic Actinomycetes?

A

Propionibacterium
Bifidobacterium
Eubacterium
Actinomyces

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3
Q

What are the 2 subgroups of aerobic actinomycetes?

A

Aerobic with mycolic acid&Aerobic with no mycolic acid

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4
Q

What are the actinomycetes with mycolic acid?

A

Corynebactericeae
Mycobactericeae
Nocardiaceae

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5
Q

What are the actinomycetes with no mycolic acid?

A
Actinomadura
Nocardiopsis
Streptomyces
Tropheryma
Thermophilic Actinomyctes
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6
Q

Which of the BİG FOUR can cause MADURA FOOT(MYCETOMA)?

A

**NOCARDİA
ACTİNOMADURA
NOCARDİOPSİS
STREPTOMYCES

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7
Q

What does tropheryma cause?

A

Whipple’s Disease—>causes malnutrition

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8
Q

What does thermophilic actinomyctes cause?

A

Farmer’s Lung(Type 2 Hypersensitivity)=

EXTRİNSİC ALLERGİC ALVEOLİTİS

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9
Q

Actinomyces is catalase___

Nocardia is catalase ____

A

-

+

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10
Q

Actinomyces and Nocardia common features?

A

Gram +

Branching bacilli

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11
Q

Actinomyces features?

A

Strictly anaerobic/facultatively anaerobic
Fastidious
Low virulence and ENDOGENOUS
NO HUMAN TO HUMAN TRANSMİSSİON

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12
Q

____ is PATHOGNOMONİC FOR ACTİNOMYCETES

A

Sulfur Granules

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13
Q

What is sulfur granule?

A

Not a virulence factor,does not contain real sulfur
Named as sulfur bcs it’s yellow/orange
THEY ARE MACROSCOPİC COLONİES OF ACTİNOMYCES WHİCH ARE CONNECTED WİTH CALCİUM PHOSPHATE

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14
Q

What are the species of actinomyces?

A
A.israelii(MOST COMMON,%50)
A.viscous
A.meyeri
A.naeslundi
A.odontolyticus
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15
Q

Which actinomyces cause molar tooth colonies?

A

A.israelii

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16
Q

Which actinomyces is CATALASE POSİTİVE?

A

A.viscous

17
Q

Which actinomyces has pigment?

A

A.odontolyticus(red-brown)

18
Q

What can actinomyces cause?

A
Chronic Granulamatous Disease
Cervicofacial actinomycosis********
Thorasic actinomycosis
Abdominal actinomycosis
Pelvic actinomycosis
CNS actinomycosis
19
Q

İn severe cases _____ penetrate into surrounding muscle and bone

A

Cervicofacial actinomycosis

20
Q

Cause of Cervicofacial actinomycosis is mainly ___

A

Poor Oral Hygiene

21
Q

Cause of Thorasic actinomycosis is mainly ___

A

Aspiration

22
Q

Cause of Pelvic actinomycosis is mainly____

A

Intrauterine devices

23
Q

As the infection progress,extensive fibrosis hardness the healed wound and it is called____

A

Woody consistency

24
Q

How does sulfur granules look w/Gram staning?

A

Hairy

25
Q

Nocardiaceae?

A
Obligate anaerobs
Acid fast bacilli(weak acids!!!! ile)
Can grow on most media
Use carbohydrate oxidatively
Dry-waxy white-orange colonies
26
Q

What are the species of Nocardia?

A

N.asteroides
N.brasiliensis
N.otidis caviarum

27
Q

Which Nocardia CAN SPREAD HEMATOGENOUSLY?

A

N.asteroides

28
Q

Nocardia is an ___genous infection

A

EXO

29
Q

Actinomyces is an ___genous infection

A

Endo

30
Q

What can nocardia cause?

A

Bronchopulmonary infections
Cutaneous infections
CNS infections(in 1/3 of bronchopulmonary infections)

31
Q

What does N.asteroides cause?

A

PRİMARY bronchopulmonary infx

SECONDARY cutaneous infx

32
Q

What are the primary skin infections of nocardia?

A

Mycetoma
Lymphocutaneous infections
Cellulitis
Subcutaneous İnfections

33
Q

What is a Lymphocutaneous infection?

A

CHRONİC cutaneous nodules+ulcerations along lymphatics.

34
Q

What does N.brasiliensis and N.otidis caviarum cause?

A

PRİMARY CUTANEOUS İNFX

35
Q

There is ___ PROGNOSİS for immunosuppressed people for NOCARDİA

A

POOR

36
Q

Nocardia is an ____ infection found usually in ___ rich in ____.

A

EXOGENOUS
SOİLS
ORGANİC MATERİAL