NCM 109 Flashcards
Is an endocrine disorder in which the pancreas cannot
produce adequate insulin to regulate body glucose levels
DIABETES MELLITUS
A state characterized by the destruction
of the beta cells in the pancreas that
usually leads to absolute insulin
deficiency.
Type 1
A state that usually arises because of
insulin resistance combined with a
relative deficiency in the production of
insulin
Type 2
A condition of abnormal glucose
metabolism that arises during pregnancy.
Possible signal of an increased risk for
type 2 diabetes later in life.
GESTATIONAL
DIABETES
A state between “normal” and “diabetes”
in which the body is no longer using
and/or secreting insulin properly.
IMPAIRED
GLUCOSE
HOMEOSTASIS
a state
when fasting plasma glucose is
at least 110 but under 126 mg/dl
Impaired fasting glucose:
a
state when results of the oral
glucose tolerance test are at
least 140 but under 200 mg/dl in
the 1-hour sample
Impaired glucose tolerance:
high glucose concentration causes extra fluid to shift
and enlarge the amount of amniotic fluid.
Hydramnios
may create birth problems at the end of the
pregnancy because of CPD.
macrosomic infant
Obesity
Age over 25 years
History of large babies (10 lb or more)
History of unexplained fetal or perinatal loss
History of congenital anomalies in previous pregnancies
History of polycystic ovary syndrome
Family history of diabetes (one close relative or two distant
ones)
Member of a population with a high risk for diabetes (Native
American, Hispanic, Asian)
RISK FACTORS FOR DEVELOPING GESTATIONAL
DIABETES:
o Greater than or equal to 126 mg/dl or a nonfasting
plasma glucose greater than or equal to 200 mg/dl
meets the threshold for the diagnosis of diabetes and
does not need confirmation.
NPO for 8 hrs. before the test
FASTING PLASMA GLUCOSE (FBS)
o Between 24 and 28 weeks’ gestation to determine if
they are at risk for gestational diabetes.
50-G GLUCOSE CHALLENGE TEST
o The woman drinks an oral 100-g glucose solution;
o A venous blood sample is then taken for glucose
determination at 1, 2, and 3 hours later.
o If two of the four blood samples collected for this test
are abnormal or the fasting value is above 95 mg/dl,
a diagnosis of diabetes is made
ORAL GLUCOSE TOLERANCE TEST (OGTT)
is an automatic pump with thin tubing,
which is placed subcutaneously, most often on the woman’s
abdomen.
insulin pump
Normal level of serum creatinine for pregnant women:
0.4 –
0.8 mg/dl