Final Pharmacology Flashcards
Refers to the type of preparation in which the drug is supplied.
Drug form
synonym to Drug preparation
- Disks of compressed drug
- Comes in a variety of shapes, colors, and may be coated to enhance swallowing, and may be
scored
Tablet
- Tablet with a special coating that resists disintegration by gastric juices
- Some drugs that are irritating to the stomach, such as aspirin, are available in
enteric-coated tablets
- Drug contained within a gelatin-type container
- Easier to swallow than noncoated tablets
- Double chamber may be pulled apart to add drug powder to soft foods or beverages for
patients who have difficulty swallowing
Capsule
- Drug particles that have various coatings that differ in the amount of time required
before the coatings dissolve. - Designed to deliver a dose of drug over an extended period of time.
- An advantage of taking a drug in the sustained-release form is the decreased frequency
of administration. - Must not be crushed or mixed with foods unless specifically allowed by the drug
manufacturer.
Sustained-release capsule or tablet
- Tablet containing palatable flavouring, indicated for a local (often soothing) effect on the
throat or mouth. - Patient is advised not to swallow a lozenge; should be allowed to slowly dissolve in the
mouth - Patient is also advised not to drink liquids for approximately 15 minutes after
administration
Lozenge (troche)
- Liquid form of medication that must be shaken well before administration because the drug
particles settle at the bottom of the bottle.
Suspension
- Liquid drug preparation that contains oils and fats in water
Emulsion
Liquid drug forms with alcohol evaporation.
* Should be tightly capped to prevent alcohol evaporation.
* Should not be available to alcoholics. Caution in small children.
Elixir
Sweetened, flavoured liquid drug form.
Syrup
- Liquid drug form in which the drug is totally and evenly dissolved
- Appearance is clear rather than cloudy or settled.
Solution
Drug suspended in a substance, such as cocoa butter, that melts at body temperature.
Suppository
Drug may be either a suspension or a solution to be administered as an enema.
Enema
Injectable Drug Form
* Drug suspended (suspension) or dissolved (solution) in a sterile vehicle.
* Quite often the solution have a sterile water base and are thus referred to as aqueous
(waterlike) solutions.
* Some solutions have an oil base (viscous solutions), which tends to cause a more
prolonged absorption time.
Liquid
Injectable Drug Solution
Dry particles of drugs that must be mixed with a sterile diluting solution to render an
injectable solution (reconstitution)
The various injection routes differ according to the type of tissues into which the drug is
deposited and the rate of absorption.
Powder
- Injected directly into a vein.
- Immediate absorption and availability to major organs renders this route a dangerous
one.
Intravenous
a small volume of drug (bolus) injected into a peripheral saline lock,
attached to a vein. Can also be injected into a port on a primary (continuous) injection
line.
IV push,
a large volume of fluids, often with drugs added, that infuses
continually into a vein.
IV infusion or IV drip,
a drug diluted in moderate volume (50-100 ml) of fluid for
intermittent infusion at specified intervals.
IV piggyback (IVPB),
- Injected into a muscle by positioning the needle and
syringe at a 90-degree angle from the skin. - Absorption is fairly rapid due to the vascularity in muscle.
IntraMuscular
- Injected into the fatty layer of tissue below the skin by
positioning the needle and syringe at a 45-degree angle
from the skin. - Sometimes, especially with self-administration or
a shorter needle, a 90-degree angle is used
Subcutaneous
- Injected just beneath the skin by positioning the needle bevel up and the syringe at a
15-degree angle from the skin. - Used primarily for allergy skin testing.
- Tuberculin (TB) skin tests (PPD) are also administered ID, and the site is inspected 48-
72 h later for hardness (induration) and swelling.
Intradermal
- Injected into a catheter that has been placed by an anesthesiologist in the epidural space
of the spinal canal. - have become a popular and widely accepted vehicle for the management of
acute postoperative pain.
Epidurals
- Injected directly into the marrow of long bones.
Intraosseous
- Drugs injected directly into the brain via a catheter (ventriculostomy)
placed in a brain ventricle.
Intraventricular
- Injected into the subarachnoid space, which contains cerebrospinal fluid
that surrounds the spibnal cord. - Drugs injected by this route are frequently anesthetics, which render a
lack of sensation to those regions of the body distal to the intraspinal
injection.
Intraspinal
- A semisolid preparation containing a drug, for external application.
- Creams are more aqueous in nature and ointments tend to be thicker or more viscous
Cream or Ointment
- A liquid preparation applied externally for the treatment of skin disorders.
- Should be patted, not rubbed, on the affected skin.
Lotion
- Preparation for external use that is rubbed on the skin as a counterirritant.
- creates a different sensation to mask pain in the skin or muscles.
Liniment
- Skin patch containing drug molecules that can be absorbed through the skin at varying
rates to promote a consistent blood level of the drug between application times.
Transdermal patch
– Drugs in sterile liquids to be applied by drops.
Eye, ear, and nose drops
– Sterile semisolid preparation, often antibiotic in nature, only
for ophthalmic use
Eye ointment
– Medicated creams, often of antibiotic or antifungal
nature, that are to be inserted vaginally with the use of a
special applicator.
Vaginal creams
– Drug suspended in a substance, such
as cocoa butter, that melts at body
temperature, for local effect.
Rectal and vaginal suppositories
– Sterile solution, often an antiseptic such as povidone-iodine solution and sterile water, used to irrigate the
vaginal canal.
Douche solution
– Tablet that is absorbed via the buccal mucosa in the mouth.
It is to be placed between the cheek and gums.
Buccal tablet
– Tablet that is absorbed via the mucosa under the
tongue.
Sublingual tablet
A route that is a very fast acting (second to IV route) and effective
route for delivering humidification and medication directly into the
respiratory system.
Inhalation route