NBS Microbiology- Immunology Flashcards
Which of the following is a phagocytic cell of the immune system? A. Basophil B. Mast cell C. Eosinophils D. Neutrophil
Neutrophil
- 3 main phagocytic cells are monocytes, macrophages and neutrophils
Which cells would degranulate in response to an allergy? A. Basophil B. Mast cell C. Eosinophils D. Neutrophil
mast cells
Which cell acts as a antigen presenting cell to T cells? A. Basophil B. Macrophage C. Neutrophil D. IL-6
Macrophage
Which of the following can inactivate the pathogen? A. Macrophage B. Neutrophil C. NK cell D. Basophil
NK cell
How many types of T cells are there?
A. 1
B. 3
C. 2
3
Which of the following triggers target cells to commit suicide? A. Regulatory T cells B. Helper T cells C. Killer T cells D. Macrophages
Killer T cells
This deals with antigen recognition and regulation; it also secretes a protein molecule (cytokine)? A. Regulatory T cells B. Helper T cells C. Killer T cells D. NK cell
Helper T cell
Histocompatibility complex protein 1 would be scanned for what is inside by \_\_\_\_\_\_\_\_? A. Regulatory T cells B. Helper T cells C. Killer T cells D. NK cell
Killer T cell
Histocompatibility complex protein 2 would be scanned for whats on the outside by\_\_\_\_\_\_\_? A. Regulatory T cells B. Helper T cells C. Killer T cells D. NK cell
Helper T cells
An Antibody binds to the part of the antigen called the \_\_\_\_\_\_\_\_? A. Fragment B. Complex zone C. Epitope D. Cytokine
Epitope
Which cells would produce cytokines and help to activate Helper T and Cytotoxic T cells? A. Dendritic cell B. Macrophage C. Neutrophil D. Mast cells
Macrophage
Which of the following presents the antigen for T cells to see? A. Mast cell B. IgE C. Neutrophil D. Histocompatibility complex protein
Histocompatibility complex protein
T/F: An Antibody killed the antigen
False
it simply tags it for death aka the kiss of death
How many proteins are a part of the complement system? A. 20 B. 15 C. 21 D. 25
20
Where are the proteins of the complement system made? A. Kidney B. Liver C. Adrenal Gland D. Heart
Liver
T/F: The complement system is slow
False
its super duper fast
Which of the following is antibody independent? A. Lectin activation pathway B. Classical pathway C. Alternative pathway D. Type 1 hypersensitivity
Alternative pathway
During the lectin activation pathway \_\_\_\_\_\_\_binds to lectin and lectin binds to \_\_\_\_\_\_\_\_ on the pathogen. A. Maltose, Lipid molecule B. Maltose, Carbohydrate molecule C. Mannose, Carbohydrate molecule D. Glucose, Carbohydrate molecule
C
mannose, Carb molecule on pathogen
Which of the following depends on an antibody for activation? A. Lectin activation pathway B. Classical pathway C. Alternative pathway D. Type 2 hypersensitivity
Classical pathway
If you were dealing with the process of neutralizing antibodies, you most likely are: A. reducing the antigen B. oxidizing the antigen C. killing the antigen D. eating the antigen
oxidizing the antigen
this is your prepare to EAT stage
The lectin activation pathway triggers inflammation after binding to the carbohydrate molecule on the antigen. This chemotactically attracts \_\_\_\_\_\_\_ to infection. A. Helper T cells B. mast cells C. Phagocytes D. Basophils
Phagocytes
The lectin pathway signals B-lymphocytes causing lysis of gram ________ bacteria and foreign epitopes.
A. Negative
B. Positive
Negative
Which type of hypersensitivity would be antibody mediated? A. Type 3 B. Type 4 C. Type 1 D. Type 2
Type 2
I AM IT
IgE would be the main responding antibody to which of the following hypersensitivities? A. Type 3 B. Type 4 C. Type 1 D. Type 2
Type 1
Type 4 also but not as prevalent, bc type 4 is delayed
Type 2 Hypersensitivity would be associated with: A. IgA and IgM B. IgG C. IgE and IgA D. IgG and IgM
D
IgG and IgM
Type 3 Hypersensitivity would be associated with: A. IgA and IgM B. IgG C. IgE and IgA D. IgG and IgM
IgG
Which hypersensitivity would you find myanstania gravis and pernicious anemia occurring? A. Type 3 B. Type 4 C. Type 1 D. Type 2
Type 2
Which hypersensitivity would involve a rejection of a tissue graft? A. Type 2 B. Type 4 C. Type 3 D. Type 1
Type 4
it may take a while (delayed) to reject it
Which hypersensitivity is immune complex mediated? A. Type 3 B. Type 4 C. Type 1 D. Type 2
Type 3
Which hypersensitivity would be T cell mediated? A. Type 3 B. Type 4 C. Type 1 D. Type 2
Type 4
If your child was diagnosed with systemic lupus erythematosus you would expect which of the following: A. Antibody mediated hypersensitivity B. Immediate hypersensitivity C. Immune complex hypersensitivity D. T cell mediated hypersensitivity
Immune complex hypersensitivity
aka Type 3
You have a patient come in with rheumatoid arthritis, this is an example of: A. Antibody mediated hypersensitivity B. Immediate hypersensitivity C. Immune complex hypersensitivity D. T cell mediated hypersensitivity
Immune Complex hypersensitivity
aka Type 3
Basophils and mast cells can be associated with: A. Antibody mediated hypersensitivity B. Immediate hypersensitivity C. Immune complex hypersensitivity D. T cell mediated hypersensitivity
immediate hypersensitivity
type 1
Which of the following could be associated with Immune Complex hypersensitivity? A. Dermatitis B. Anaphylaxis C. Blood group incompatibility D. Rheumatic fever
Rheumatic fever
SARS had an outbreak in what country in 2002? A. Chile B. United States C. Africa D. Chine
China
The Avian flu (bird flu) broke out in ASIA in what year? A. 2003 B. 2004 C. 2000 D. 2001
2003
As of 2013, which of the following was named the most common foodborne disease? A. Hantavirus B. Tuberculosis C. Norovirus D. West Nile virus
Norovirus
As of 2013, what is the 2nd most common foodborne disease? A. Salmonella B. Rotavirus C. Norovirus D. Pertusis
Samonella
\_\_\_\_\_\_\_\_\_ is caused by proteins from mold or plant spores. A. Asthma B. SLE C. Rheumatic fever D. Hay fever
Hay fever
Allergic individuals who produce more IgE antibodies are referred to as: A. Atopic B. Ectopic C. Mellitus D. Recipients
Atopic
What is caused by dust mites, cockroaches, rodents and household pets? A. Asthma B. Myasthenia Gravis C. Rheumatic fever D. Hay fever
Asthma
Which of the following would attach to IgE antibodies? A. Dendritic cells B. Eosinophils C. Basophils D. Monocytes
Basophils
These are involved with chronic allergic responses: A. Mast cells B. Eosinophils C. Basophils D. Monocytes
Eosinophils
How long will IgE live in the blood? A. several weeks B. 1 week C. 1 day D. 1 year
1 day
How long wtih IgE live after it has been attaching to a Mast cell? A. several weeks B. 1 week C. 1 day D. 1 year
several weeks
T/F: Being more susceptible to allergies can be hereditary
True
Which autoimmune disease would involve the myoneural junction causing double vision or a face drooping appearance? A. SLE B. Multiple Sclerosis C. Insulin-dependent diabetes mellitus D. Myasthenia gravis
D
Myasthenia Gravis
Myasthenia gravis deals with self-reactive antibodies that bind to receptors for \_\_\_\_\_\_\_\_\_? A. Sodium B. Ca++ C. Acetylcholine D. Potassium
Acetylchloine
Which of the following is NOT an autoimmune disease? A. Multiple Sclerosis B. Systemic Lupus Erythematosus C. DiGeorge Syndrome D. Canale- Smith Syndrome E. Myasthenia Gravis
DiGeorge syndrome
*its an immunodeficiency
Which antibodies are most commonly found with rheumatoid arthritis? A. IgE and IgA B. IgA and IgG C. IgM and IgG D. IgA and IgM
IgM and IgG
What do the antibodies in rheumatoid arthritis activate?
Macrophages
Which of the following best describes Canale-smith syndrome:
A. Organ specific immune disease targeting B cells
B. Destruction of the myelin sheath
C. Repeatedly stimulated lymphocytes and swollen nodes
D. Inflammation of the lungs, arthritis, kidney damage
C
Canale- Smith lymph is swollll
Which of the following best describes Multiple Sclerosis:
A. Organ specific immune disease targeting B cells
B. Destruction of the myelin sheath
C. Repeatedly stimulated lymphocytes and swollen nodes
D. Inflammation of the lungs, arthritis, kidney damage
B
Destruction of the myelin sheath
Which of the following best describes Systemic Lupus Erythematosus?
A. Organ specific immune disease targeting B cells
B. Destruction of the myelin sheath
C. Repeatedly stimulated lymphocytes and swollen nodes
D. Inflammation of the lungs, arthritis, kidney damage
D
Inflammation of the lungs, arthritis and kidney damage
Red facial rash or a malar butterfly rash is seen with which disease? A. Rhematoid Arthritis B. DiGeorge Syndrome C. Systemic Lupus Erythematosus D. Myasthenia Gravis
C
SLE
This disease is caused by the breakdown of B and T cells that make IgG antibodies? A. Systemic Lupus Erythematosus B. DiGeorge Syndrome C. Canale- Smith Syndrome D. Myasthenia Gravis
A
SLE
Multiple Scleosis effects primarily the ________?
A. CNS
B. PNS
CNS
This disease deals with self active T cells that can cross the blood brain barrier? A. Systemic Lupus Erythematosus B. DiGeorge Syndrome C. Multiple Sclerosis D. Myasthenia Gravis
Multiple Sclerosis
Which disease is more prevalent in women and can result in hair loss, paralysis and convulsions? A. Rhematoid Arthritis B. DiGeorge Syndrome C. Systemic Lupus Erythematosus D. Myasthenia Gravis
C
SLE
Which disease deals with absent or severely reduced Thymic tissue and NO t cells?
A. AIDS
B. severe combined immunodeficiency syndrome
C. DiGeorge Syndrome
D. Karposi Sarcoma
DiGeorge Syndrome
You are born with no B or T cells. wWhat would you have?
A. AIDS
B. severe combined immunodeficiency syndrome
C. DiGeorge Syndrome
D. Karposi Sarcoma
B
Severe combines immunodeficiency syndrome
*REALLY BAD
Kaposi Sarcoma is associated with: A. AIDS B. severe combined immunodeficiency syndrome C. DiGeorge Syndrome D. SLE
AIDS
Which causative agent is associated with AID and HIV? A. Pneumocystic Carnii B. Polio virus C. Norovirus D. Coxsackie virus
A
Pneumocystic Carnii
This is an example of a live attenuated virus?
A. Salk
B. Sabin
Sabin
Salk treated polio virus with formaldehyde to ______ the virus.
A. Enchance
B. Kill
Kill
salK - Kills
AIDS is caused by: A. HIV-3 B. HPV-1 C. HIV-2 D HIV-1
D
HIV-1
Noninfectious vaccines help to generate all of the following EXCEPT?
A. Memory B cells
B. Memory T helper cells
C. Memory T killer cells
Memory T Killer
What type of vaccine uses a weakened form of the microbe? A. DNA Vaccine B. Carrier Vaccine C. Attenuated Vaccine D. Non-infectious Vaccine
Attenuated Vaccine
Attenuated vaccines help to generate which of the following?
A. Memory B cells
B. Memory T helper cells
C. Memory T killer cells
Memory T killer
The vaccine for rubella, mumps, and measles is an example of: A. DNA Vaccine B. Carrier Vaccine C. Attenuated Vaccine D. Non-infectious Vaccine
Attenuated Vaccine
This type of vaccine is genetically engineered and introduces a single gene from pathogenic microbe into a virus? A. DNA Vaccine B. Carrier Vaccine C. Attenuated Vaccine D. Non-infectious Vaccine
Carrier Virus
T/F: Does a carrier vaccine cause disease
False
What type of vaccine is referred to as "the trojan horse"? A. DNA Vaccine B. Carrier Vaccine C. Attenuated Vaccine D. Non-infectious Vaccine
Carrier vaccine
Injecting a flu virus gene would describe which vaccine? A. DNA Vaccine B. Carrier Vaccine C. Attenuated Vaccine D. Non-infectious Vaccine
DNA Vaccine
This type of immunity is either attenuated or killed?
A. Active immunity
B. Passive-active immunity
C. Passive immunity
Active immunity
The type of immunity would occur naturally and can be found in mothers milk or via administered preformed antibodies in immune globulins?
A. Active immunity
B. Passive-active immunity
C. Passive immunity
Passive immunity is natural
Both immuno globulins (aka immunoglobulins, gamma globulins) & vaccines are associated with which type of immunity?
A. Active immunity
B. Passive-active immunity
C. Passive immunity
Passive-Active
Immunodiffusion testing is also called: A. Immunoelectrophoresis B. Ouchterlony test C. Agglutination D. Complement fixation test
B
Ouchterolony test
This type of testing separates the molecule in order to look for a particular class of antibodies? A. Immunoelectrophoresis B. Ouchterlony test C. Agglutination D. Complement fixation test
A
Immunoelectrophoresis
Multiple myeloma, AIDS and lyme disease (borrelia burgdorferi) can be detected using which type of test? A. Complement Fixation test B. ELISA C. Western Blot D. Immunoelectrophoresis
D
Immunoelectrophoresis
Which of the following would involve antigen-antibody mixed, insoluble, huge complex formed? A. Precipitates B. Immunodiffusion C. Agglutination D. ELISA
Precipitates
This Test is used for influenze and mononucleosis, it clumps red blood cells and is NOT an antibody-antigen reaction: A. Agglutination B. Western Blot test C. Viral Hemagglutination test D. Viral Neutralizaton
C
Viral Hemaggulination test
This test uses a dye an is commonly used to detect syphillis and mycobacterium TB: A. Agglutination B. Western Blot test C. Complement Fixation test D. Fluorescent Antibody test
D
Fluorescent Antibody test
Western blot (aka imunnoblot) verifies the presence of antibodies against \_\_\_\_\_\_\_\_. A. Fungal Antigens B. HIV C. Red Blood cells D. Influenze
HIV
What Color will gram positive bacteria stain? A. Red B. Safranin C. Purple D. Blue
purple
This test detects the presence of specific antibodies in serum: A. Agglutination B. Western Blot test C. Complement Fixation test D. Fluorescent Antibody test
C
Complement Fixation test
T/F: Rapid ELISAs are immunofiltration assays
True
Which of the following is actually an example of an electrophoresis test? A. ELISA B. Fluorescent antibody test C. Western Blot D. Viral Neutralization
C
Western Blot
This is used in pregnancy testing and blood typing? A. Agglutination B. Western Blot test C. Complement Fixation test D. Fluorescent Antibody test
A
Agglutination
When assessing things like meningitis, gonorrhea, salmonellosis, brucellosis and thyphoid fever you would be using which of the following: A. Agglutination B. Western Blot test C. Complement Fixation test D. Fluorescent Antibody test
A
Agglutination
Which color would be seen in a counterstain? A. Red B. Safranin C. Purple D. Blue
Safranin
Which color would Gram negative stain? A. Red B. Safranin C. Purple D. Blue
Red
What type of rinse would be used as a decolorizer?
alcohol rinse
QUIZ: What would present antigen to T cell…..
Macrophage
QUIZ: Analphylaxis is seen in what hypersensitivity?
Type 1- immediate
QUIZ: You would find infections and dermatitis in which hypersensitivity?
Type 4- delayed (T cell mediated)
QUIZ: What type of cells inactive pathogens?
NK cells
QUIZ: This is the part of the antigen that the immune system recognizes…
Epitope
What is nike’s logo?
Just do it