Natural Selection & Speciation Flashcards
Week 32 Quiz
5 factors that signify evolution within a population
- Genetic mutation
- Gene flow (immigration)
- Non-random mating
- Genetic drift (separation of population)
- Selection (predator vs. prey)
Define ‘population’
organisms that interbreed to create fertile offspring
Define ‘gene pool’
A collection of alleles in a population
Define ‘allele frequency’
Commonality of allele; how often it appears
Define ‘evolution’
Major changes in alleles; changes in a population over time
What must be true in order for a population to not be evolving?
- The population is large
- there is no migration/gene flow
- random mating (no sexual selection)
- no natural selection
What does the Hardy-Weinberg Theorem have to do with?
Determining allele frequency
Frequency of homo dominant allele equation
p x p = p^2
Frequency of homo recessive allele equation
q x q = q^2
Frequency of hetero allele equation
pq + qp = 2pq
100% of a population (equation of dominant/recessive traits)
1 = p^2 + 2pq + q^2
Equation that will not be on the test ( = 100% of gene pool)
p + q = 1
Transcription factors are
regulatory genes
Activators in gene expression…
bind to DNA to increase operon (regulatory & structural gene) transcription
When does most gene regulation occur in Eukaryotes?
Transcription during or after RNA/protein production (translation)
Gene Regulation Method 1: Turning on/off access to DNA
limits chromatin accessibility; relaxed chromatin allows for transcription better than not
Gene Regulation Method 2: Switching on/off transcription factors
Activators or repressors turn on/off genes; turn on/off responses to outside information
Define ‘gene expression’
DNA is converted into a functional structure (protein); how cells respond to environment; decides protein production/volume; structure and function
Components of gene expression
Promoter, operator, regulatory genes, transcription factors, repressors
Promoter
Where RNA polymerase binds on DNA to initiate transcription
Operator
DNA segment controlling RNA access to promoter (controlled transcription)
Operon
Promoter + operator + structural genes
Inhibitor/repressor protein
attaches to operator to inhibit transcription (RNA reaching structural genes)
In order for proteins (genes to be expressed) to be made in response to environmental signals…
… RNA polymerase must reach the structural genes
Define ‘genome’
Complete genetic material
Advantage of gene expression
conservation of resources
Why is gene expression different in eukaryotes than prokaryotes
Eukaryotes have bigger genomes, multiple chromosomes, specialized cells, and less operons
Site of transcription in Eukaryotes
euchromatin
Does all of a chromatin strand uncoil?
No, some are fixed and tightly coiled so they can’t be translated
What segments lie beyond the promoter in Eukarotic genes?
Introns (transcribed and not translated (made into a protein))
Exons (transcribed and translated)
On in Eukaryotes, after transcription (that makes pre-mRNA), introns are _____ and exons _____
removes, splice (join) one another to make mRNA
Intron removal from pre-mRNA can be catalyzed by
ribozymes
Transciption factors may still directly control transciption as it occurs by…
placing RNA polymerase on the promoter, or by binding to enhancers that may loop around and touch RNA polymerase and the promoter.
Define ‘cell differentiation’
cells develp with specialized functions; the growth of tissues to produce a characteristical form is called morphogenesis.
Homeotic Genes
position anatomical structures during morphogenesis; translate into regulator proteins that control patters of developmental genes and adjust rates of cell division.
Homeobox Sequence
Homeoboxes (DNA sequence inside homeotic genes) code for protein regulators. Mutations cause developmental abnormalities. Organisms have similar homeoboxes throughout their body.