Naloxone Flashcards
1
Q
Therapeutic Classification
A
Opioid (narcotic) antagonist
2
Q
Pharmacologic Classification
A
Opioid overdose agent
3
Q
Mechanism of Action
A
Competes with opioid agonists for mu and kappa receptors
- Antagonizes all effects of morphine and other opioids.
- Reverses respiratory depression and coma.
4
Q
Indications
A
- Opioid overdose
- Postoperatively to reverse opioids given during surgery
5
Q
Contraindications
A
Hypersensitivity
6
Q
Precautions
A
- Chronic physical dependence to opioids
- Cardiovascular disease
- Seizure disorders
7
Q
pregnancy category?
A
Pregnancy Category C
8
Q
Drug interaction with tramadol?
A
Use with tramadol can increase risk of seizures.
9
Q
Drug interactions with opioids?
A
Reverses all effects of opioids.
10
Q
Common Adverse Effects
A
No common adverse effects.
11
Q
Serious Adverse Effects
A
- tachycardia
- dysrhythmia
- HTN
- nausea
- vomiting
12
Q
Nursing Considerations
A
- Assess respiratory status
- Resuscitation equipment available
- Monitor for signs of withdrawal
- Assess vital signs, pain level, pupil size
- Be prepared for respiratory arrest
