Aminocaproic Acid Flashcards
1
Q
Therapeutic Classification
A
Hemostatic/antifibrinolytic
2
Q
Pharmacologic Classification
A
None
3
Q
Mechanism of Action
A
Occupies binding sites on plasminogen and plasmin. Prevents digestion of fibrin clot by plasmin.
4
Q
Indications
A
- Aplastic anemia
- Hepatic cirrhosis
- Postoperative cardiac surgery
- Certain carcinomas
- Hemophilia A
5
Q
Contraindications
A
- History of CVA in last 3 months
- Recent trauma/surgery
- Active bleeding
- Severe HTN
- Intracranial neoplasm
- AV malformation
6
Q
Drug interaction with thrombolytic agents?
A
Antagonizes action of thrombolytic agents
7
Q
Interactions with estrogens and oral contraceptives?
A
Hypercoagulation
8
Q
Interactions with Factor IX?
A
Increased risk of thrombosis and acute MI
9
Q
Adverse effects
A
- *Rhabdomyolysis
- myopathy
- hypotension
- bradycardia
10
Q
Nursing Considerations
A
- Complete health history
- Check IV site frequently for extravasation
- Observe for thrombophlebitis
- Assess for signs of myopathy
- Monitor vital signs and urine output
11
Q
Patient & Family Teaching
A
- Immediately report adverse effects
- Make position changes slowly
- Observe for increased toxicity with oral contraceptives and estrogen
- Immediately notify if pregnancy suspected
- Do not breastfeed
12
Q
pregnancy category?
A
Pregnancy Category C
