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Unit II Nursing 160 > Acetaminophan > Flashcards

Acetaminophan Flashcards

1
Q

Therapeutic Classification

A

Nonopioid analgesic, antipyretic

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2
Q

Pharmacologic Classification

A

Para-aminophenol derivative

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3
Q

Mechanism of Action

A

Inhibits COX

  • May inhibit chemical mediators of pain
  • Direct action on the heat-regulating center of the hypothalamus
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4
Q

Indications

A
  • Mild to moderate pain
  • Osteoarthritis of the hip or knee
  • Dysmenorrhea
  • Dental procedures
  • Headache and myalgia
  • Fevers
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5
Q

Contraindications

A
  • Allergy to acetaminophen
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6
Q

Precautions

A
  • Anemia
  • G6PD deficiency
  • Hepatic disease
  • Rheumatoid or osteoarthritis
  • Malnutrition
  • Bone marrow depression
  • Immunosuppression
  • Renal impairment
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7
Q

pregnancy category?

A

Pregnancy Category B

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8
Q

Interactions with alcohol?

A

Increased hepatotoxicity.

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9
Q

Drug interactions with barbituates, carbamazepine, diphenylhyantoin, isoniazid, rifampin, and sulfinpyrazone?

A

Additive effect.

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10
Q

Drug interaction with Iamotrigine (an anti-seizure med)?

A

Will decrease levels of Iamotrigine if drugs are administered concurrently.

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11
Q

Drug interaction with warfarin?

A

Can increase hyperthrombinemic effects of warfarin.

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12
Q

Drug interaction with zidovudine (an HIV med)?

A

Can increase risk of bone marrow suppression.

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13
Q

Drug interaction with echinacea?

A

Hepatoxicity reported with echinacea/

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14
Q

Adverse Effects

A

At recommended doses, acetaminophen is well tolerated.

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15
Q

Serious Adverse Effects

A
  • acute hepatic failure
  • acute acetaminophen poisoning, with symptoms such as anorexia, nausea, diaphoresis, or abdominal pain
  • Chronic use → Neutropenia, pancytopenia, leucopenia, thrombocytopenia purpura, hepatoxicity in alcoholics, renal damage
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16
Q

Nursing Considerations

A
  • Assess recent drug history
  • Assess effectiveness of the medication
  • Perform baseline and periodic liver function tests (AST & ALT) & monitor for signs of hepatotoxicity
  • Assess alcohol use
17
Q

Patient & Family Teaching

A
  • Do not increase the dose or take the drug more frequently
  • Seek immediate medical attention for a fever lasting more than 3 days
  • Do not drink alcohol
  • Report any signs of potential liver toxicity
  • Keep drug in a secure location away from small children

Unit II Nursing 160 (16 decks)

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