Clopidegrol Flashcards
1
Q
Therapeutic Classification
A
Antiplatelet agent
2
Q
Pharmacologic Classification
A
ADP receptor blocker
3
Q
Mechanism of Action
A
Inhibits ADP receptors on platelets and prolongs bleeding time by irreversibly inhibiting platelet aggregation.
4
Q
Indications
A
- Reduce risk of CVA/MI
- Reducing thrombolytic events post- CVA/MI
- Prevent DVT
- Prevent thrombi formation unstable angina/coronary stents
5
Q
Contraindications
A
Active bleeding
6
Q
Precautions
A
- High risk of bleeding (incl. those with peptic ulcer disease)
- Severe hepatic disease – may impair the ability of the liver to convert the drug to its active metabolite.
7
Q
Adverse Effects
A
- *Abnormal bleeding
- Flu-like symptoms
- headache
- diarrhea
- dizziness
- bruising
- URTI
- Rash
- Pruritius
8
Q
Drug interactions with anticoagulants, other antiplatelet agents, thrombolytic agents, or NSAIDs (incl. aspirin)?
A
Increased risk of bleeding
9
Q
Interactions with drugs that inhibit hepatic metabolic enzymes?
A
May diminish antiplatelet action
10
Q
Interactions with feverfew, green tea, gingko, fish oil, ginger, or garlic?
A
Increased risk of bleeding
11
Q
Nursing Considerations
A
- Assess current use of anticoagulants and NSAIDs
- Assess for increased bleeding risk
- Monitor for bleeding
- Evaluate unexpected fever/infection
12
Q
Patient & Family Teaching
A
- Immediately report unusual bleeding
- Know it may take long to stop bleeding
- Do not stop taking drug
- Do not use NSAIDs, other OTC medications, or herbal supplements
- Inform dentist and other care providers prior to procedures.
13
Q
pregnancy category?
A
Pregnancy Category B
