N37/N38 Flashcards

1
Q

cerebellar functions

A

equilibrium and coordination of eye movements
maintenance of posture and muscle tone
coordinating and adjusting motor movements
planning voluntary movements
learned movements

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2
Q

Cerebellar assists in movements on the _____ side of the body

A

ipsilateral

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3
Q

3 lobes of cerebellum

A

anterior, posterior, flocculonodular lobe

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4
Q

Inferior cerebellar peduncle

A

spinal cord and inferior olive afferents (some vestibular efferents)

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5
Q

Middle cerebellar peduncle

A

pontocerebellar projection afferents of contralateral pontine nuclei

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6
Q

Superior cerebellar peduncle

A

efferents from deep cerebellar nuclei to thalamus and red nucleus

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7
Q

3 layers of cerebellar cortex (grey matter)

A

molecular layer, purkinje cell layer, granular layer

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8
Q

Molecular layer has

A

cell-free superior layer and purkinje dendrites + granule axons + interneurons

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9
Q

Purkinje cell layer has

A

purkinje cells in single continuous row that project to cerebellar cortex

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10
Q

Granular cell layer

A

granule cells that act as interneurons to EXCITE purkinjes

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11
Q

Cerebellar medullary layer

A

white matter: cerebellar afferents, efferents and deep cerebellar nuclei

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12
Q

cerebellar afferents (2 types)

A

climbing fibers and mossy fibers

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13
Q

Climbing fibers

A

contralateral IO nucleus –> inferior peduncle –> purkinje cell dendrites (carrying training info of movements)

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14
Q

Mossy fibers

A

enter at all sites, include all other afferents, project to granule cells (carry “state” information of muscles)

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15
Q

Cerebellar efferents

A

Purkinje axons to deep cerebellar nuclei, deep cerebellar nuclei –> sup. peduncle –> red nucleus and VLN of the thalamus OR –> juxtarestiform body –> ipsilateral vestibular nuclei and reticular formation

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16
Q

4 deep cerebellar nuclei in white matter

A

fastigial nucleus, globose nucleus, emboliform nucleus, dentate nucleus

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17
Q

Mossy fibers

A

terminate on granule cells–> purkinje cells of molecular layer and collateral branches excite deep cerebellar nuclei (state of muscle)

18
Q

Input to IO from

A

premotor and primary motor cortices and red nucleus –> IO –> contralateral purkinje cells and collateral branches excite deep cerebellar nuclei (state of muscle)

19
Q

MF and CF to cerebellum are used for

A

learning and identifying patterns of activity

20
Q

Interneurons

A

except granule cells, rest are inhibitory

21
Q

Purkinje cells

A

inhibit deep cerebellar nuclei while collateral branches of MF and CF are excitatory

22
Q

Spinocerebellar tracts

A

unconscious proprioception and touch information (limb position, joint angle, muscle tension and length)

23
Q

Spinocerebellar tracts for LE

A

Dorsal and Ventral Spinocerebellar tracts (DSCT and VSCT)

24
Q

Spinocerebellar tracts for UE

A

Cuneocerebellar tract and Rostral spinocerebellar tract

25
Q

Dorsal Spinocerebellar tract receptors

A

touch, pressure, and proprioception –> Ia and Ib axons

26
Q

Dorsal Spinocerebellar tract primary neuron

A

periphery –> medial dorsal root entry zone –> Clarke’s nucleus

27
Q

Dorsal Spinocerebellar tract secondary neuron

A

clarke’s nucleus (C8-L2/3) –> ipsilateral DSCT–> inferior cerebellar peduncle –>vermis

28
Q

DSCT conveys

A

fine coordination of posture and movement of lower limb

29
Q

Ventral Spinocerebellar tract receptors

A

golgi tendon organs

30
Q

Ventral Spinocerebellar tract primary neuron

A

type Ib–>DRG -> medial entry zone–> synapse on spinal border cells

31
Q

Ventral Spinocerebellar tract secondary neuron

A

decussate at anterior white commissure –> VSCT –> superior cerebellar peduncle –> decussate to ipsilateral vermis

32
Q

VSCT conveys

A

coordinated movement movement and posture of entire lower limb

33
Q

Cuneocerebellar tract receptors

A

proprioception (muscle spindles and golgi tendon organs)

34
Q

Cuneocerebellar tract primary neuron

A

Type Ia and Ia –> DRG–> medial entry zone –> fasciculus cuneatus –>synapses on cuneatus nucleus

35
Q

Cuneocerebellar tract secondary neuron

A

cuneate nucleus (Clarke’s nucleus homolog)–>ipsilateral cunceocerebellar tract –> inferior cerebellar peduncle –> vermis

36
Q

Cuneocerebellar tract conveys

A

fine coordination of posture and movement of UE

37
Q

Rostral Spinocerebellar Tract primary neuron

A

Type Ib –> DRG –> medial entry zone –> synapse on spinal gray matter

38
Q

Rostral Spinocerebellar Tract secondary neuron

A

spinal gray matter –> ipsilateral rostral spinocerebellar tract–> inferior cerebellar peduncle –> vermis

39
Q

Rostral Spinocerebellar Tract conveys

A

coordinated movement movement and posture of entire upper limb (VSCT of lower limb)

40
Q

Vestibulocerebellum

A

flocculonodular lobe and fastigial nucleus, ipsilaterall vestibular nuclei and responds back via direct or indirect (fastigial/juxtarestiform body) modulation of vestibular function and eye movements

41
Q

Spinocerebellum

A

Vermis, fastigial, globose, emboliform nuclei, ipsilateral spinal cord, ipsilateral trigeminal, and contralateral M-I, for coordination of planned movement and current position and tone