Mycology - Exam 3 Flashcards

1
Q

fungi characteristics

A

no chlorophyll/photosynthesis, nucleus (eukary), produces spores, cellulose, chitin, reproduction: asexual (imperfect), sexual (perfect), heterotrophs (aerobic & facultative anaerobic)

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2
Q

beneficial effects of fungi

A

decomposition, biosynthetic factories, antibiotics, model organisms, recombinant DNA technology, edible, nutritional supplements, flavor, alkaloids, malaria control

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3
Q

harmful effects of fungi

A

destruction, diseases, toxins, spoilage, damage

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4
Q

fruit rot is also called

A

botrytis

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5
Q

fungi can also be biocontrol agents against insect pests

A

white muscardine disease

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6
Q

3 types of poisonous mushrooms

A

death cap, liberty cap “magic mushroom”, fly agaric

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7
Q

fungi rigid cell wall contains

A

glucan, mannan, chitin; sterols, 80s ribosomes

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8
Q

most common body structures are

A

multicellular filaments (mold) and single cells (yeast)

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9
Q

dimorphic shape means

A

both mold & yeast

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10
Q

mold: vegetative mycelium

A

inside, provides support, absorbs nutrients

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11
Q

mold: aerial/reproductive mycelium

A

support the fruiting bodies/reproductive structures

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12
Q

thallus/mycelia: what are the 2 types of hyphae within it

A

septate & non septate

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13
Q

hyphae

A

long filaments of cells joined together

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14
Q

yeast structure

A

nonfilamentous, unicellular, spherical, oval, budding

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15
Q

what are pseudohyphae

A

when yeast buds fail to detach

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16
Q

dimorphic fungi change from

A

mycelial form to yeast due to temperature shifts

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17
Q

sexual reproduction

A

2 haploids, meiosis

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18
Q

asexual reproduction

A

most common, effective, mitosis, sporulation, fragmentation, budding, gametangium

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19
Q

example of a pathogenic fungi

A

ringworm

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20
Q

opportunistic fungi

A

seldom cause disease unless something is underlying allows for it to happen

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21
Q

in the parasitic state, only ________________ are seen

A

hyphae & arthrospores

22
Q

routes of entry

A

nasal, lungs, blood vessels, stomach, intestines, skin

23
Q

deep mycoses

A

systemic: brain, lungs, heart, spleen, liver, kidney, cutaneous

24
Q

superficial mycosis

A

outer skin layer, no immune response, caused mostly by yeast i.e.: tinea versicolor & white/black piedra

25
Q

cutaneous mycosis “dermatophytoses”

A

epidermal layers, evoke immune response, i.e.: ringworm, athlete’s foot, jock itch

26
Q

subcutaneous mycosis

A

chronic infection of subdermal tissues

27
Q

deep/systemic mycosis

A

mostly originating in the lung by inhalation caused by virulent dimorphic fungi i.e.: valley fever, cave disease, blasto

28
Q

blasto

A

systemic fungal disease caused by inhalation of spores from sandy soil, decaying wood, etc.

29
Q

tinea versicolor

A

yeast that naturally occurs on the skin, overpopulates causing white blotches on skin

30
Q

opportunistic mycosis caused by

A

numerous fungi widespread in nature

31
Q

4 common fungal infections in animals

A

ringworm, aspergillosis, candidiasis, blastomycosis

32
Q

opportunistic mycosis: candidiasis

A

most common one, can be superficial or deep, alimentary or IVC portal of entry for deep, predisposing factors: chemo, long term antibiotic use, steroids

33
Q

antifungal agent

A

selectively eliminates fungal pathogens from a host with minimal toxicity to the host

34
Q

polyene antifungal drugs

A

amphotericin, sterols, cell membrane

35
Q

azole antifungal drugs

A

fluconazole, inhibit cytochrome enzymes involved with biosynthesis of ergosterol

36
Q

allylamine & morpholine antifungal drugs

A

terbinafine, inhibit ergosterol biosynthesis

37
Q

antimetabolite antifungal drugs

A

inhibit DNA & RNA synthesis

38
Q

mycotoxins

A

toxic secondary metabolites produced by fungi, colonize crops, alphatoxins

39
Q

rye mold produces

A

Claviceps purpurea, ergot which leads to ergotism (convulsive symptoms, Salem Witch trials), i.e.: rye, barley, cereal

40
Q

aspergillus produce

A

alphatoxin

41
Q

dermatophytes

A

parasitizing only keratinized epidermal structures, zoonotic, human/animal/soil resevoir i.e.: ringworm

42
Q

ways to treat fungal infections

A

isolate infected animals
lime sulfur/miconazole shampoo
clip hair
itraconazole, fluconazole, griseofulvin, terbinafine
toss contaminated bedding, clean grooming equip.
no vax in dogs/cats yet

43
Q

what 3 things regulate dimorphism

A

pH, [CO2], temperature

44
Q

fungal diseases classified by

A

mode of entry & degree of tissue involvement

45
Q

aspergillosis common in which animals

A

cattle, horse, poultry

46
Q

which 3 fungi can cause ringworm

A

microsporum, trichophyton, epidermophyton

47
Q

microsporidia are what type of parasites

A

obligate intracellular protozoans

48
Q

microsporidians infect what animals most

A

arthropods and fish

49
Q

microsporidian are related to

A

fungi

50
Q

T/F microsporidia are spore-forming

A

True

51
Q

examples of horizontal transmission

A

adult bees ingest spores as result of comb cleaning OR fish and shrimp exposed to microsporidia spores via gut or gills

52
Q

example of vertical transmission

A

direct transfer of infection from parent to progeny (offspring)